Dr Stephen Makin
MBChB, FRCP, PhD
Senior Lecturer (Clinical)
- Email Address
- stephen.makin@abdn.ac.uk
- Office Address
Centre for Rural Health
The Centre for Health Science
Old Perth Road
Inverness
IV2 3JH- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
As well as my clinical academic work, I am a geriatrician with my clinical practice at Catihness General Hospital in Wick a small rural hospital in the far north of Scotland.
After training at the University of Birmingham, and post graduate training in North West England, I moved to Scotland to do a Clinical Research fellow post at the University of Edinburgh. My PhD focused on small vessel disease. Diffuse vascular disease that is very common in older people, and is responsible for vascular dementia, lacunar stroke, gait instablity as well as other co-morbidities.
I am still interested in stroke but in addition I am now also investigating the best way to deliever health care to frail elderly patients in remote and rural areas.
I am always keen to collaborate and welcome enquires from prospective collaborators and research students.
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Increased risk of recurrent stroke in patients with impaired kidney function: results of a pooled analysis of individual patient data from the MICON international collaboration
Molad, J., Miwa, K., Nash, P. S., Ambler, G., Best, J., Wilson, D., Hallevi, H., Fandler-Höfler, S., Eppinger, S., Du, H., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Goeldlin, M. B., Beyeler, M., Bücke, P., El-Koussy, M., Mattle, H. P., Panos, L. D., van Dam-Nolen, D. H. K., Dubost, F., Hendrikse, J., Kooi, M. E., Mess, W., Nederkoorn, P. J., Shiozawa, M., Christ, N., Bellut, M., Gunkel, S., Karayiannis, C., Van Ly, J., Singhal, S., Slater, L., Kim, Y. D., Song, T., Lee, K., Lim, J., Hara, H., Nishihara, M., Tanaka, J., Yoshikawa, M., Demirelli, D. S., Tanriverdi, Z., Uysal, E., Coutts, S. B., Chappell, F. M., Makin, S., Mak, H. K., Teo, K. C., Wong, D. Y. K., MICON international collaborationJournal of Neurology, Neurosurgery & PsychiatryContributions to Journals: ArticlesClinical Relevance of ‘Cap’ and ‘Track’ Development after Recent Small Subcortical Infarct
Cheng, Y., Arteaga-Reyes, C., Clancy, U., Garcia, D. J., Valdés Hernández, M. D. C., Thrippleton, M. J., Stringer, M. S., Blair, G. W., Wiseman, S., Chappell, F. M., Zhang, J., Liu, X., Jochems, A. C., Maniega, S. M., Sakka, E., Bastin, M. E., Brown, R., Loos, C. M., Makin, S. D., Liu, M., Wu, B., Doubal, F. N., Wardlaw, J. M., MSS-2, MSS-3 and the INVESTIGATE-SVDs Study GroupAnnals of NeurologyContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/ana.27182
- [ONLINE] View publication in Scopus
Prediction of white matter hyperintensities evolution one-year post-stroke from a single-point brain MRI and stroke lesions information
Rachmadi, M. F., Valdés-Hernández, M. d. C., Makin, S., Wardlaw, J., Skibbe, H.Scientific Reports, vol. 15, 1208Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41598-024-83128-6
- [ONLINE] View publication in Scopus
Sex Differences in Frequency, Severity, and Distribution of Cerebral Microbleeds
Fandler-Höfler, S., Eppinger, S., Ambler, G., Nash, P., Kneihsl, M., Lee, K., Lim, J., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., Wong, A., Kim, Y. D., Song, T., Lemmens, R., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Ben Assayag, E., Hallevi, H., Molad, J., Nishihara, M., Tanaka, J., Coutts, S. B., Polymeris, A., Wagner, B., Seiffge, D. J., Lyrer, P., Kappelle, L. J., Salman, R. A., Hernandez, M. V., Jäger, H. R., Lip, G. Y. H., Fischer, U., El-Koussy, M., Mas, J., Legrand, L., Makin, S., Gattringer, T., Microbleeds International Collaborative NetworkJAMA Network Open, vol. 7, no. 10, e2439571Contributions to Journals: ArticlesImpact of co-resident health and living alone on risk of hospital admission for people with Parkinson’s disease
Brack, C., Tenison, E., Henderson, E., Makin, S., Ben-Shlomo, Y.Parkinsonism & Related Disorders, vol. 127, 107084Contributions to Journals: ArticlesStatin Therapy for Secondary Prevention in Ischemic Stroke Patients with Cerebral Microbleeds
Prats-Sanchez, L., Camps-Renom, P., Nash, P. S., Wilson, D., Ambler, G., Best, J. G., Guasch-Jiménez, M., Ramos-Pachón, A., Martinez-Domeño, A., Lambea-Gil, ?., Díaz, G. E., Guisado-Alonso, D., Du, H., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y., Ay, H., Jung, S., Bornstein, N. M., Gattringer, T., Eppinger, S., Van Dam-Nolen, D. H., Koga, M., Toyoda, K., Fluri, F., Phan, T. G., Srikanth, V. K., Heo, J. H., Bae, H. J., Kelly, P. J., Imaizumi, T., Staals, J., Köhler, S., Yakushiji, Y., Orken, D. N., Smith, E. E., Wardlaw, J. M., Chappell, F. M., Makin, S. D., Mas, J. L., Calvet, D., Bordet, R., Chen, C. P., Veltkamp, R., Kandiah, N., Simister, R. J., De Leeuw, F. E., Engelter, S. T., Peters, N., Soo, Y. O., Microbleeds International Collaborative Network (MICON)Neurology, vol. 102, no. 7, e209173Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1212/WNL.0000000000209173
- [ONLINE] View publication in Scopus
Clinical Associations and Prognostic Value of MRI-Visible Perivascular Spaces in Patients With Ischemic Stroke or TIA: A Pooled Analysis
Best, J. G., Ambler, G., Wilson, D., Du, H., Lee, K. J., Lim, J. S., Teo, K. C., Mak, H., Kim, Y. D., Song, T. J., Selcuk Demirelli, D., Nishihara, M., Yoshikawa, M., Kubacka, M., Zietz, A., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y., Panos, L., Goeldlin, M. B., Slater, L. A., Karayiannis, C. C., Phan, T. G., Bellut, M., Abrigo, J., Cheng, C., Leung, T. W., Chu, W., Chappell, F., Makin, S. D., Van Dam-Nolen, D. H., Kooi, M. E., Köhler, S., Staals, J., Kuchcinski, G., Bordet, R., Dubost, F., Wardlaw, J. M., Soo, Y. O., Fluri, F., Srikanth, V. K., Jung, S., Peters, N., Hara, H., Yakushiji, Y., Necioglu Orken, D., Heo, J. H., Lau, G. K. K., Bae, H. J., Werring, D. J.Neurology, vol. 102, no. 1, e207795Contributions to Journals: ArticlesValidated frailty measures using electronic primary care records: a review of diagnostic test accuracy
Brack, C., Kynn, M., Murchie, P., Makin, S.Age and Ageing, vol. 52, no. 11, afad173Contributions to Journals: ArticlesSex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke
Exalto, L. G., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H. J., Best, J. G., Bordet, R., Chen, C. P., Van Der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K., Hilal, S., Huenges Wajer, I. M., Kim, J., Kappelle, L. J., Kim, B. J., Köhler, S., De Kort, P. L., Koudstaal, P. J., Lim, J. S., Makin, S. D., Mok, V. C., Van Oostenbrugge, R. J., Roussel, M., Staals, J., Valdés-Hernández, M. D. C., Venketasubramanian, N., Verhey, F. R., Wardlaw, J. M., Werring, D. J., Xu, X., Van Zandvoort, M. J., Biesbroek, J. M., Chappell, F. M., Biessels, G. J.Stroke, vol. 54, no. 9, pp. 2296-2303Contributions to Journals: ArticlesImpact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation
Soo, Y., Zietz, A., Yiu, B., Mok, V. C. T., Polymeris, A. A., Seiffge, D., Ambler, G., Wilson, D., Leung, T. W. H., Tsang, S. F., Chu, W., Abrigo, J., Cheng, C., Lee, K., Lim, J., Shiozawa, M., Koga, M., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H., Collet, R., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., Wong, A., Kim, Y. D., Song, T., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Demirelli, D. S., Bornstein, N. M., Assayag, E. B., Hallevi, H., Molad, J., Nishihara, M., Tanaka, J., Coutts, S. B., Kappelle, L. J., Al-Shahi Salman, R., Jager, R., Lip, G. Y. H., Goeldlin, M. B., Panos, L. D., Mas, J., Legrand, L., Karayiannis, C., Phan, T., Bellut, M., Chappell, F., Makin, S., Hayden, D., Williams, D., van Dam-Nolen, D. H. K., Nederkoorn, P. J., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Mendyk, A., Köhler, S., van Oostenburgge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F., Simister, R., Hendrikse, J., Wardlaw, J., Kelly, P., Fluri, F., Srikanth, V., Calvet, D., Jung, S., Kwa Vincent, I. H., Smith, E. E., Hara, H., Yakushiji, Y., Orken, D. N., Fazekas, F., Thijs, V., Heo, J., Veltkamp, R., Ay, H., Imaizumi, T., Lau, K. K., Jouvent, E., Toyoda, K., Yoshimura, S., Bae, H., Martí-Fàbregas, J., Prats-Sánchez, L., Lyrer, P., Best, J., Werring, D., Engelter, S. T., Peters, N., Network, t. M. I. C.Annals of Neurology, vol. 94, no. 1, pp. 61-74Contributions to Journals: ArticlesDevelopment of a UK core dataset for geriatric medicine research:: a position statement and results from a Delphi consensus process
Welch, C., Wilson, D., Sayer, A. A., Witham, M. D., Jackson, T. A., Rajkumar, R., Dhesi, J., Lochlainn, M. N., Aspray, T., Dodds, R., Frith, J., Richardson, S., Tullo, E., Yarnall, A., Walker, R., Cunningham, E., Prynn, J., Patel, H., Tiwari, D., Makin, S., Myint, P., Henderson, E., Keevil, V., Walesby, K., Allan, L., Masoli, J., Quinn, T., Clegg, A. P., Hale, M., Conroy, S., Taylor, J., Gladman, J., Gordon, A., Harwood, R., Cox, N., Roberts, H., UK Geriatric Medicine Core Dataset Extended Working GroupBMC Geriatrics, vol. 23, 168Contributions to Journals: ArticlesPredicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models
Li, R., Harshfield, E. L., Bell, S., Burkhart, M., Tuladhar, A. M., Hilal, S., Tozer, D. J., Chappell, F. M., Makin, S. D., Lo, J. W., Wardlaw, J. M., de Leeuw, F. E., Chen, C., Kourtzi, Z., Markus, H. S.Cerebral Circulation - Cognition and Behavior, vol. 5, 100179Contributions to Journals: ArticlesDIAGNOSTIC TEST ACCURACY OF FRAILTY SCREENING TOOLS USING DATA IN ELECTRONIC PRIMARY CARE RECORDS
Makin, S., Brack, C., Kynn, M., Murchie, P.Age and Ageing, vol. 51, no. SUPPL 2, 1013Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1093/ageing/afac125.005
Network impact score is an independent predictor of post-stroke cognitive impairment: a multicenter cohort study in 2341 patients with acute ischemic stroke.
Weaver, N. A., Aben, H. P., Kuijf, H. J., Abrigo, J., Bae, H., Barbay, M., Best, J. G., Bordet, R., Chappell, F. M., Chen, C. P., Dondaine, T., van der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K., Hilal, S., Huenges Wajer, I. M., Kang, Y., Kappelle, L. J., Kim, B. J., Köhler, S., de Kor, P. L., Koudstaal, P. J., Kuchcinski, G., Lam, B. Y., Lee, B., Lee, K., Lim, J., Lopes, R., Makin, S., Mendyk, A., Mok, V. C., Oh, M. S., Van Oostenbrugge, R. J., Roussel, M., Shi, L., Staals, J., Valdés Hernández, M. D. C., Venketasubramanian, N., Verhey, F. R., Wardlaw, J. M., Werring, D. J., Xin, X., Yu, K., van Zandvoort, M. J., Zhao, L., Biessels, G. J., Biesbroek, J.NeuroImage: Clinical, vol. 34, 103018Contributions to Journals: ArticlesImpact of Small Vessel Disease Progression on Long-term Cognitive and Functional Changes after Stroke
Clancy, U., Makin, S. D., McHutchison, C. A., Cvoro, V., Chappell, F. M., Hernández, M. D. C., Sakka, E., Doubal, F., Wardlaw, J. M.Neurology, vol. 98, no. 14, pp. E1459-E1469Contributions to Journals: ArticlesTracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors
Stringer, M. S., Heye, A. K., Armitage, P. A., Chappell, F., Valdés Hernández, M. d. C., Makin, S. D., Sakka, E., Thrippleton, M. J., Wardlaw, J. M.NeuroImage: Clinical, vol. 32, 102883Contributions to Journals: ArticlesPotential recruitment into a clinical trial of vascular secondary prevention medications in cerebral small vessel disease, based on concomitant medication use
Morrison, E., Lyall, D. M., Pell, J. P., Mackay, D. F., Doubal, F. N., Wardlaw, J. M., Quinn, T. J., Makin, S.Cerebral Circulation - Cognition and Behavior, vol. 2, 100015Contributions to Journals: ArticlesA four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage
Bernal, J., Valdés-Hernández, M. d., Escudero, J., Heye, A. K., Sakka, E., Armitage, P. A., Makin, S., Touyz, R. M., Wardlaw, J. M., Thrippleton, M. J.Neuroimage, vol. 230, 117786Contributions to Journals: ArticlesDevelopment of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies
Best, J. G., Ambler, G., Wilson, D., Lee, K., Lim, J., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martinez-Domeno, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., Wong, A., Kim, Y. D., Song, T., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Ben Assayag, E., Hallevi, H., Molad, J., Nishihara, M., Tanaka, J., Coutts, S. B., Polymeris, A., Wagner, B., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, L. J., Salman, R. A., Jager, H. R., Lip, G. Y. H., Fischer, U., El-Koussy, M., Mas, J., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F. M., Makin, S., Hayden, D., Williams, D. J., Mess, W. H., Nederkoorn, P. J., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, A. C., Yatawara, C., Mendyk, A., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F., Simister, R., Hendrikse, J., Calvet, D., Jung, S., Kwa, V. I. H., Engelter, S. T., Peters, N., Fazekas, F., Thijs, V., Heo, J. H., Mok, V., Veltkamp, R., Ay, H., Imaizumi, T., Gomez-Anson, B., Lau, K. K., Jouvent, E., Rothwell, P. M., Toyoda, K., Bae, H., Marti-Fabregas, J., Werring, D. J., Microbleeds Int CollaborativeThe Lancet neurology, vol. 20, no. 4, pp. 294-303Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S1474-4422(21)00024-7
Lacunar Stroke Lesion Extent and Location and White Matter Hyperintensities Evolution 1 Year Post-lacunar Stroke
Valdés Hernández, M. d. C., Grimsley-Moore, T., Sakka, E., Thrippleton, M. J., Chappell, F. M., Armitage, P. A., Makin, S., Wardlaw, J. M.Frontiers in Neurology, vol. 12, 640498Contributions to Journals: ArticlesPost-stroke cognition at 1 and 3 years is influenced by the location of white matter hyperintensities in patients with lacunar stroke
Valdés Hernández, M. D. C., Grimsley-Moore, T., Chappell, F. M., Thrippleton, M. J., Armitage, P. A., Sakka, E., Makin, S., Wardlaw, J. M.Frontiers in Neurology, vol. 12, 634460Contributions to Journals: ArticlesProbabilistic Deep Learning with Adversarial Training and Volume Interval Estimation - Better Ways to Perform and Evaluate Predictive Models for White Matter Hyperintensities Evolution
Rachmadi, M. F., Valdés-Hernández, M. d. C., Maulana, R., Wardlaw, J., Makin, S., Skibbe, H.Chapters in Books, Reports and Conference Proceedings: Conference Proceedings- [ONLINE] DOI: https://doi.org/10.1007/978-3-030-87602-9_16
- [ONLINE] View publication in Scopus
The use of transcranial ultrasound and clinical assessment to diagnose ischaemic stroke due to large vessel occlusion in remote and rural areas.
Antipova, D., Eadie, L., Makin, S., Shannon, H., Wilson, P., MacAden, A.PloS ONE, vol. 15, no. 10, e0239653Contributions to Journals: ArticlesGrowing research in geriatric medicine: a trainee perspective
Welch, C., Geriatric Medicine Research Collaborative, Makin, S.Age and Ageing, vol. 49, no. 5, pp. 733-737Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afaa052
- [ONLINE] http://europepmc.org/abstract/med/32516393
- [ONLINE] View publication in Scopus
Preparing for a challenging winter 2020/21
Yiangou, A., Makin, S., Cope, C., Laycock, E.The Academy of Medical Sciences. 79 pagesBooks and Reports: Other ReportsAutomatic spatial estimation of white matter hyperintensities evolution in brain MRI using disease evolution predictor deep neural networks
Rachmadi, M. F., Valdés-Hernández, M. D. C., Makin, S., Wardlaw, J., Komura, T.Medical image analysis, vol. 63, pp. 101712Contributions to Journals: ArticlesPredictors of Lesion Cavitation After Recent Small Subcortical Stroke.
Gattringer, T., Valdes, H. M., Heye, A., Armitage, P., Makin, S., Chappell, F., Pinter, D., Doubal, F., Enzinger, C., Fazekas, F., Wardlaw, J.Translational Stroke Research, vol. 11, pp. 402-411Contributions to Journals: ArticlesAnalysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease
Bernal, J., Valdés-Hernández, M., Escudero, J., Viksne, L., Heye, A., Armitage, P., Makin, S., Touyz, R., Wardlaw, J.Magnetic Resonance Imaging, vol. 66, pp. 240-247Contributions to Journals: ArticlesThe Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study
Weaver, N. A., Zhao, L., Biesbroek, J. M., Kuijf, H. J., Aben, H. P., Bae, H. J., Caballero, M. A. A., Chappell, F. M., Chen, C., Dichgans, M., Duering, M., Georgakis, M. K., van der Giessen, R. S., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Vom Hofe, E. M., de Kort, P. L. M., Koudstaal, P. J., Lam, B. Y. K., Lim, J. S., Makin, S. D. J., Mok, V. C. T., Shi, L., Valdes Hernandez, M. C., Venketasubramanian, N., Wardlaw, J. M., Wollenweber, F. A., Wong, A., Xin, X., Meta, V. C. I. M. c., Biessels, G. J.Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, vol. 11, pp. 310-326Contributions to Journals: ArticlesAccuracy of the short-form Montreal Cognitive Assessment: Systematic review and validation
McDicken, J. A., Elliott, E., Blayney, G., Makin, S., Ali, M., Larner, A. J., Quinn, T. J., Collaborators, V.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, vol. 34, no. 10, pp. 1515-1525Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/gps.5162
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
- [ONLINE] Deposit in Glasgow Uni repository
Intensive Blood Pressure Lowering in Patients With Renal Impairment and Lacunar Stroke
Makin, S., Whiteley, W. N.Journal of the American Heart Association, vol. 8, no. 16, e013637Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/JAHA.119.013637
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12772/1/Makin_etal_JAHA_VOR.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies
Wilson, D., Ambler, G., Lee, K., Lim, J., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sánchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., Wong, A., Kim, Y. D., Song, T., Schrooten, M., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Assayag, E. B., Hallevi, H., Tanaka, J., Hara, H., Coutts, S. B., Hert, L., Polymeris, A., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, J., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Mattle, H. P., Panos, L. D., Mas, J., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F., Makin, S., Hayden, D., Williams, D. J., Kooi, M. E., van Dam-Nolen, D. H. K., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, C., Yatawara, C., Mendyk, A., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F., Simister, R., van der Lugt, A., Kelly, P. J., Wardlaw, J. M., Soo, Y., Fluri, F., Srikanth, V., Calvet, D., Jung, S., Kwa, V. I. H., Engelter, S. T., Peters, N., Smith, E. E., Yakushiji, Y., Orken, D. N., Fazekas, F., Thijs, V., Heo, J. H., Mok, V., Veltkamp, R., Ay, H., Imaizumi, T., Gomez-Anson, B., Lau, K. K., Jouvent, E., Rothwell, P. M., Toyoda, K., Bae, H., Marti-Fabregas, J., Werring, D. J., Harkness, K., Shaw, L., Sword, J., Mohd Nor, A., Sharma, P., Kelly, D., Harrington, F., Randall, M., Smith, M., Mahawish, K., Elmarim, A., Esisi, B., Cullen, C., Nallasivam, A., Price, C., Barry, A., Roffe, C., Coyle, J., Hassan, A., Birns, J., Cohen, D., Sekaran, L., Parry-Jones, A., Parry, A., Hargroves, D., Proschel, H., Datta, P., Darawil, K., Manoj, A., Burn, M., Patterson, C., Giallombardo, E., Smyth, N., Mansoor, S., Anwar, I., Marsh, R., Ispoglou, S., Chadha, D., Prabhakaran, M., Meenakishundaram, S., O'Connell, J., Scott, J., Krishnamurthy, V., Aghoram, P., McCormick, M., Sprigg, N., O'Mahony, P., Cooper, M., Choy, L., Wilkinson, P., Leach, S., Caine, S., Burger, I., Gunathilagan, G., Guyler, P., Emsley, H., Davis, M., Manawadu, D., Pasco, K., Mamun, M., Luder, R., Sajid, M., Okwera, J., Warburton, E., Saastamoinen, K., England, T., Putterill, J., Flossman, E., Power, M., Dani, K., Mangion, D., Suman, A., Corrigan, J., Lawrence, E., Vahidassr, D., Shakeshaft, C., Brown, M., Charidimou, A., Cohen, H., Banerjee, G., Houlden, H., White, M., Yousry, T., Flossmann, E., Muir, K., El-Koussy, M., Gratz, P., Molad, J., Korczyn, A., Kliper, E., Maeder, P., Gass, A., Pachai, C., Bracoub, L., Douste-Blazy, M., Fratacci, M. D., Vicaut, E., Sato, S., Miwa, K., Fujita, K., Ide, T., Ma, H., Ly, J., Singhal, S., Chandra, R., Slater, L., Soufan, C., Moran, C., Traenka, C., Thilemann, S., Fladt, J., Gensicke, H., Bonati, L., Kim, B. J., Han, M., Kang, J., Ko, E., Yang, M. H., Jang, M. S., Murphy, S., Carty, F., Akijian, L., Thornton, J., Schembri, M., Douven, E., Delgado, M., Escudero, R., Marín, R., Camps-Renom, P., Guisado-Alonso, D., Nuñez, F., Medrano-Martorell, S., Merino, E., Iida, K., Ikeda, S., Nishihara, M., Irie, H., Demirelli, D. S., Medanta, J. M., Zerna, C., Hernández, M. V., Armitage, P., Heye, A., Muñoz-Maniega, S., Sakka, E., Thrippleton, M., Dennis, M., Beigneux, Y., Silva, M., Venketasubramanian, N., Ho, S. L., Cheung, R. T. F., Chan, K. H., Teo, K. C., Hui, E., Kwan, J. S. K., Chang, R., Tse, M. Y., Hoi, C. P., Chan, C. Y., Chan, O. L., Cheung, R. H. K., Wong, E. K. M., Leung, K. T., Tsang, S. F., Ip, H. L., Ma, S. H., Ma, K., Fong, W. C., Li, S. H., Li, R., Ng, P. W., Wong, K. K., Liu, W., Wong, L., Ramos, L., De Schryver, E., Jöbsis, J., van der Sande, J., Brouwers, P., Roos, Y., Stam, J., Bakker, S., Verbiest, H., Schoonewille, W., Linn, C., Hertzberger, L., van Gemert, M., Berntsen, P., Hendrikse, J., Nederkoorn, P., Mess, W., Koudstaal, P., Leff, A., Ward, N., Nachev, P., Perry, R., Ozkan, H., Mitchell, J.The Lancet neurology, vol. 18, no. 7, pp. 653-665Contributions to Journals: ArticlesPredicting the Evolution of White Matter Hyperintensities in Brain MRI using Generative Adversarial Networks and Irregularity Map
Rachmadi, M., MdC, V., Makin, S., Wardlaw, J., Komura, T.9 pages.Other Contributions: Other Contributions- [ONLINE] DOI: https://doi.org/10.1101/662692
- [ONLINE] http://europepmc.org/abstract/PPR/PPR81533
Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images
Ortiz-Ramon, R., Valdes Hernandez, M. D. C., Gonzalez-Castro, V., Makin, S., Armitage, P. A., Aribisala, B. S., Bastin, M. E., Deary, I. J., Wardlaw, J. M., Moratal, D.Comput Med Imaging Graph, vol. 74, pp. 12-24Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/30921550
- [ONLINE] DOI: https://doi.org/10.1016/j.compmedimag.2019.02.006
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12851/1/OrtizRamon_etal_CompMedImGr_identification_of_the_presence_VOR.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Stability of Estimated Premorbid Cognitive Ability over Time after Minor Stroke and Its Relationship with Post-Stroke Cognitive Ability
McHutchison, C. A., Chappell, F. M., Makin, S., Shuler, K., Wardlaw, J. M., Cvoro, V.Brain Sciences, vol. 9, no. 5, 117Contributions to Journals: ArticlesGrowing research in geriatric medicine
Witham, M. D., Roberts, H. C., Gladman, J., Stott, D. J., Sayer, A. A., Aspray, T. J., Brock, P., Clegg, A., Cox, N., Ewan, V., Frith, J., Burton, J. K., Jackson, T., Lewis, E. G., Lim, S. E., Makin, S., Lochlainn, M. N., Richardson, S., Shenkin, S. D., Steves, C. J., Todd, O., Tullo, E., Walker, R., Yarnall, A., Extended Working Group from the NIHR Newcastle Biomedical Research Centre MeetingAge and Ageing, vol. 48, no. 3, pp. 316-319Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afy220
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
- [ONLINE] Deposit in Edinburgh Uni repository
Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke
Valdes Hernandez, M. d. C. V., Case, T., Chappell, F. M., Glatz, A., Makin, S., Doubal, F., Wardlaw, J. M.International Journal of Molecular Sciences, vol. 20, no. 6, 1293Contributions to Journals: ArticlesComprehensive Geriatric Assessment in hospital and hospital-at-home settings: a mixed-methods study
Gardner, M., Shepperd, S., Godfrey, M., Mäkelä, P., Tsiachristas, A., Singh-Mehta, A., Ellis, G., Khanna, P., Langhorne, P., Makin, S., Stott, D. J.Health Services and Delivery Research, vol. 7, no. 10, pp. 1-236Contributions to Journals: ArticlesConvolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI
Ulas, C., Das, D., Thrippleton, M. J., Valdes Hernandez, M. d. C., Armitage, P. A., Makin, S. D., Wardlaw, J. M., Menze, B. H.Frontiers in Neurology, vol. 9, 1147Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/30671015
- [ONLINE] DOI: https://doi.org/10.3389/fneur.2018.01147
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12854/1/Ulas_etal_fneur_09_01147_VOR.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke
McHutchison, C. A., Cvoro, V., Makin, S., Chappell, F. M., Shuler, K., Wardlaw, J. M.Journal of Neurology, Neurosurgery & Psychiatry, vol. 90, no. 4, pp. 436-443Contributions to Journals: ArticlesThe brain health index: Towards a combined measure of neurovascular and neurodegenerative structural brain injury
Dickie, D. A., Valdes Hernandez, M. d. C., Makin, S. D., Staals, J., Wiseman, S. J., Bastin, M. E., Wardlaw, J. M.International Journal of Stroke, vol. 13, no. 8, pp. 849-856Contributions to Journals: ArticlesManaging blood pressure in older adults: Age alone is no barrier to treatment
Makin, S., Stott, D. J.BMJ (Online), vol. 362, k2912Contributions to Journals: Editorials- [ONLINE] DOI: https://doi.org/10.1136/bmj.k2912
- [ONLINE] View publication in Scopus
The impact of early-life intelligence quotient on post stroke cognitive impairment
Makin, S. D. J., Doubal, F. N., Shuler, K., Chappell, F. M., Staals, J., Dennis, M. S., Wardlaw, J. M.European Stroke Journal , vol. 3, no. 2, pp. 145-156Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/31008346
- [ONLINE] DOI: https://doi.org/10.1177/2396987317750517
- [ONLINE] Deposit in Edinburgh Uni repository
Long-term morphological changes of symptomatic lacunar infarcts and surrounding white matter on structural magnetic resonance imaging
Loos, C. M., Makin, S. D., Staals, J., Dennis, M. S., Van Oostenbrugge, R. J., Wardlaw, J. M.Stroke, vol. 49, no. 5, pp. 1183-1188Contributions to Journals: ArticlesThe effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke
Makin, S. D., Doubal, F. N., Quinn, T. J., Bath, P. M., Dennis, M. S., Wardlaw, J. M.European Stroke Journal , vol. 3, no. 1, pp. 66-73Contributions to Journals: ArticlesThe relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke
Loos, C. M., McHutchison, C., Cvoro, V., Makin, S. D., Staals, J., Chappell, F., Dennis, M., van Oostenbrugge, R. J., Wardlaw, J. M.International Journal of Stroke, vol. 13, no. 5, pp. 518-524Contributions to Journals: ArticlesSmall Vessel Disease and Dietary Salt Intake: Cross-Sectional Study and Systematic Review
Makin, S. D. J., Mubki, G. F., Doubal, F. N., Shuler, K., Staals, J., Dennis, M. S., Wardlaw, J. M.Journal of Stroke and Cerebrovascular Diseases, vol. 26, no. 12, pp. 3020-3028Contributions to Journals: ArticlesWhite matter hyperintensity reduction and outcomes after minor stroke
Wardlaw, J. M., Chappell, F. M., Valdes Hernandez, M. d. C., Makin, S. D. J., Staals, J., Shuler, K., Thrippleton, M. J., Armitage, P. A., Munoz-Maniega, S., Heye, A. K., Sakka, E., Dennis, M. S.Neurology, vol. 89, no. 10, pp. 1003-1010Contributions to Journals: ArticlesApplication of Texture Analysis to Study Small Vessel Disease and Blood-Brain Barrier Integrity
Valdes Hernandez, M. d. C., Gonzalez-Castro, V., Chappell, F. M., Sakka, E., Makin, S., Armitage, P. A., Nailon, W. H., Wardlaw, J. M.Frontiers in Neurology, vol. 8, 327Contributions to Journals: ArticlesReliability of an automatic classifier for brain enlarged perivascular spaces burden and comparison with human performance
Gonzalez-Castro, V., Valdes Hernandez, M. d. C., Chappell, F. M., Armitage, P. A., Makin, S., Wardlaw, J. M.Clinical Science, vol. 131, no. 13, pp. 1465-1481Contributions to Journals: ArticlesBlood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study
Wardlaw, J. M., Makin, S. J., Valdés Hernández, M. C., Armitage, P. A., Heye, A. K., Chappell, F. M., Muñoz-Maniega, S., Sakka, E., Shuler, K., Dennis, M. S., Thrippleton, M. J.Alzheimer's and Dementia, vol. 13, no. 6, pp. 634-643Contributions to Journals: ArticlesSample size considerations for trials using cerebral white matter hyperintensity progression as an intermediate outcome at 1 year after mild stroke: results of a prospective cohort study
Chappell, F. M., Valdes Hernandez, M. d. C., Makin, S. D., Shuler, K., Sakka, E., Dennis, M. S., Armitage, P. A., Munoz Maniega, S., Wardlaw, J. M.Trials, vol. 18, 78Contributions to Journals: ArticlesIntegrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease
Munoz Maniega, S., Chappell, F. M., Valdes Hernandez, M. C., Armitage, P. A., Makin, S. D., Heye, A. K., Thrippleton, M. J., Sakka, E., Shuler, K., Dennis, M. S., Wardlaw, J. M.Journal of Cerebral Blood Flow and Metabolism, vol. 37, no. 2, pp. 644-656Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/26933133
- [ONLINE] DOI: https://doi.org/10.1177/0271678X16635657
STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease
Sachdev, P. S., Lo, J. W., Crawford, J. D., Mellon, L., Hickey, A., Williams, D., Bordet, R., Mendyk, A., Gele, P., Deplanque, D., Bae, H., Lim, J., Brodtmann, A., Werden, E., Cumming, T., Kohler, S., Verhey, F. R. J., Dong, Y., Tan, H. H., Chen, C., Xin, X., Kalaria, R. N., Allan, L. M., Akinyemi, R. O., Ogunniyi, A., Klimkowicz-Mrowiec, A., Dichgans, M., Wollenweber, F. A., Zietemann, V., Hoffmann, M., Desmond, D. W., Linden, T., Blomstrand, C., Fagerberg, B., Skoog, I., Godefroy, O., Barbay, M., Roussel, M., Lee, B., Yu, K., Wardlaw, J., Makin, S. J., Doubal, F. N., Chappell, F. M., Srikanth, V. K., Thrift, A. G., Donnan, G. A., Kandiah, N., Chander, R. J., Lin, X., Cordonnier, C., Moulin, S., Rossi, C., Sabayan, B., Stott, D. J., Jukema, J. W., Melkas, S., Jokinen, H., Erkinjuntti, T., Mok, V. C. T., Wong, A., Lam, B. Y. K., Leys, D., Henon, H., Bombois, S., Lipnicki, D. M., Kochan, N. A.Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, vol. 7, pp. 11-23Contributions to Journals: ArticlesCerebral blood flow in small vessel disease: A systematic review and meta-analysis
Shi, Y., Thrippleton, M. J., Makin, S. D., Marshall, I., Geerlings, M. I., de Craen, A. J., van Buchem, M. A., Wardlaw, J. M.Journal of Cerebral Blood Flow and Metabolism, vol. 36, no. 10, pp. 1653-1667Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/27496552
- [ONLINE] DOI: https://doi.org/10.1177/0271678X16662891
Response to Letter Regarding Article, "Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review"
Makin, S. D., Wardlaw, J. M.Stroke, vol. 47, no. 3, pp. e54Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/26786112
- [ONLINE] DOI: https://doi.org/10.1161/STROKEAHA.115.012258
Tracer kinetic modelling for DCE-MRI quantification of subtle blood-brain barrier permeability
Heye, A. K., Thrippleton, M. J., Armitage, P. A., Valdes Hernandez, M. d. C., Makin, S. D., Glatz, A., Sakka, E., Wardlaw, J. M.Neuroimage, vol. 125, pp. 446-455Contributions to Journals: ArticlesBlood pressure and sodium: Association with MRI markers in cerebral small vessel disease
Heye, A. K., Thrippleton, M. J., Chappell, F. M., Hernandez Mdel, C., Armitage, P. A., Makin, S. D., Maniega, S. M., Sakka, E., Flatman, P. W., Dennis, M. S., Wardlaw, J. M.Journal of Cerebral Blood Flow and Metabolism, vol. 36, no. 1, pp. 264-274Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/25899292
- [ONLINE] DOI: https://doi.org/10.1038/jcbfm.2015.64
A comparison of location of acute symptomatic vs. 'silent' small vessel lesions
Valdes Hernandez, M. d. C., Maconick, L. C., Munoz Maniega, S., Wang, X., Wiseman, S., Armitage, P. A., Doubal, F. N., Makin, S., Sudlow, C. L., Dennis, M. s., Deary, I. J., Bastin, M., Wardlaw, J. M.International Journal of Stroke, vol. 10, no. 7, pp. 1044-1050Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/26120782
- [ONLINE] DOI: https://doi.org/10.1111/ijs.12558
Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review
Makin, S. D., Doubal, F. N., Dennis, M. S., Wardlaw, J. M.Stroke, vol. 46, no. 11, pp. 3142-3148Contributions to Journals: ArticlesCerebral small vessel disease and renal function: systematic review and meta-analysis
Makin, S. D. J., Cook, F. A. B., Dennis, M. S., Wardlaw, J. M.Cerebrovascular Diseases, vol. 39, no. 1, pp. 39-52Contributions to Journals: ArticlesStroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden
Staals, J., Makin, S. D., Doubal, F. N., Dennis, M. S., Wardlaw, J. M.Neurology, vol. 83, no. 14, pp. 1228-1234Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/25165388
- [ONLINE] DOI: https://doi.org/10.1212/WNL.0000000000000837
Predicting delirium after a stroke
Makin, S. D., Wardlaw, J.Journal of Neurology, Neurosurgery & Psychiatry, vol. 85, no. 4, 357Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/24039025
- [ONLINE] DOI: https://doi.org/10.1136/jnnp-2013-305379
Variation in risk factors for recent small subcortical infarcts with infarct size, shape, and location
Del Bene, A., Makin, S. D. J., Doubal, F. N., Inzitari, D., Wardlaw, J. M.Stroke, vol. 44, no. 11, pp. 3000-3006Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pubmed/24008573
- [ONLINE] DOI: https://doi.org/10.1161/STROKEAHA.113.002227
Cognitive impairment after lacunar stroke: systematic review and meta-analysis of incidence, prevalence and comparison with other stroke subtypes
Makin, S. D. J., Turpin, S., Dennis, M. S., Wardlaw, J. M.Journal of Neurology, Neurosurgery & Psychiatry, vol. 84, no. 8, pp. 893-900Contributions to Journals: ArticlesDystypia in acute stroke not attributable to aphasia or neglect
Cook, F. A. B., Makin, S. D. J., Wardlaw, J., Dennis, M. S.BMJ Case Reports, vol. 2013, bcr2013200257Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bcr-2013-200257
- [ONLINE] PubMed