Lecturer
- About
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- Email Address
- riko.hatakeyama@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437359
- Office Address
Institute of Medical Sciences
University of Aberdeen
Foresterhill
Aberdeen
AB25 2ZD
Scotland, UK
Office: 2.30.1
Lab: 2.06
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
2020- Lecturer, University of Aberdeen, UK (Group leader; Assistant Professor equivalent)
2014-2020 Postdoctoral Fellow, University of Fribourg, Switzerland (with Prof Claudio De Virgilio)
2011-2014 Postdoctoral Fellow, Brandeis University, USA (with Prof Satoshi Yoshida)
2006-2011 PhD student, The University of Tokyo, Japan (with Prof Tatsuya Maeda)
2002-2006 Undergraduate student, The University of Tokyo, Japan (with Prof Katsuhiko Kitamoto)
Memberships and Affiliations
- Internal Memberships
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- Foresterhill Biological Safety Committee
- External Memberships
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- British Society for Cell Biology Ambassador
- Scottish Microscopy Society Committee
- Research
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Research Overview
Cell Growth Signalling in Space
I study how individual cells sense and respond to environmental changes. My particular focus is the Target of Rapamycin (TOR, or mTOR) kinase, which adjusts cell growth in response to diverse external stimuli such as nutrients, hormones and stresses.
TOR regulates a wide range of cellular processes operating at diverse subcellular locations ("organelles"). I want to understand how TOR receives signals from, and sends signals to, different locations. By combining various techniques of genetics, biochemistry, cell biology and bioinformatics in yeast and mammalian cell models, our lab tries to fill the existing gap between the signalling and the organelle research fields.
Selected publications
- Hatakeyama R. (2021) Pib2 as an emerging master regulator of yeast TORC1. Biomolecules. 11: 1489. review.
- Hatakeyama R, Péli-Gulli MP, Hu Z, Jaquenoud M, Garcia Osuna GM, Sardu A, Dengjel J, De Virgilio C. (2019) Spatially distinct pools of TORC1 balance protein homeostasis. Molecular Cell. 73:325-338.
Research Areas
Accepting PhDs
I am currently accepting PhDs in Biomedical Sciences.
Please get in touch if you would like to discuss your research ideas further.
Biomedical Sciences
Accepting PhDsResearch Specialisms
- Biochemistry
- Cell Biology
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
Supervision
Current Lab Members
- Colin Ferguson (Technician, 2024-)
- Samuel Atkinson (Postdoctoral fellow, 2022-)
- Kenji Muneshige (PhD student, 2022-)
- William Ritchie (PhD student, 2022-)
Past Lab Members
- Megan Robertson (Technician, 2022-2024)
- Shoki Fujita (Visiting postdoctoral fellow, 2023)
- Eri Hirata (Visiting postdoctoral fellow, 2021)
- Sotonye Krukrubo (Masters project student, 2024)
- Fidan Huseynzade (Masters project student, 2024)
- Saran Babooraj (Masters project student, 2023; Research assistant, 2024)
- Aolat Adetosoye (Masters project student, 2022)
- Yiqi Cai (Masters project student, 2021)
- Camelia Filip (Undergraduate project student, 2024)
- Alexandra-Ioana Ondrea (Undergraduate project student, 2024)
- Eleftheria Moschou (Undergraduate project student, 2023)
- Gregor Barr (Undergraduate project student, 2023)
- Trami Nielsen (Undergraduate summer student, 2022)
- Daniel Paterson (Undergraduate project student, 2021)
- Patryk Marcinkowski (Undergraduate project student, 2021)
Interested in joining us? I am always looking for talented personnel with diverse backgrounds. There are plenty of exciting projects waiting for you!
Postdocs and PhD students: I constantly seek funding to recruit motivated postdocs and PhD students. If you are interested in our research, contact me (riko.hatakeyama@abdn.ac.uk) with your CV. Please be specific on what you want to do in my lab. When there is a good fit, we can discuss potential options such as pending grant applications and available fellowships or studentships.
Masters and undergraduate students: Students of the University of Aberdeen have chances to join our lab via project allocation processes. We may also accept full-year Research Masters students (https://www.abdn.ac.uk/smmsn/postgraduate/research/masters-by-research-in-biomedical-sciences-1228.php#panel1248), so please get in touch with me (riko.hatakeyama@abdn.ac.uk) if you are interested in this program.
Funding and Grants
Research Grants as the Principal Investigator
- BBSRC New Investigator Research Grant (2022-2025), "Separate pools for distinct outputs: Division of labour in the TORC1 cell growth signalling pathway", £662,283.
- Royal Society of Edinburgh SAPHIRE Fund (2024), "The origin of autophagosome", £8,367.
- BBSRC International Partnering Awards (2023-2024), "How G-protein coupled receptors regulate TORC1 pathway: Does receptor trafficking signal cell growth?", £22,487.
- Daiwa Foundation Small Grant (2021), "Short stay of an early-career scientist for research collaboration (regulatory mechanism of Rho protein)", £2,850.
- Wellcome Trust ISSF Seed Corn Fund (2021), "Visualizing the subcellular postcode PI(3,5)P2", £7,300.
Research Grants as a Co-Investigator
- Tenovus Scotland Research Grant (2023-2024), "Combatting multidrug resistance: Inducing degradation of multidrug transporters in the pathogenic fungus Candida glabrata", PI: Dr Takashi Kubota, £12,000.
- Teaching
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