Professor Mary MacLeod
BSc MBChB PhD FRCP
Personal Chair (Clinical)
- Email Address
- m.j.macleod@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437842
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Dr Macleod is a Clinical Pharmacologist with a personal chair (Teaching and Research) at the University of Aberdeen and honorary Consultant Physician within NHS Grampian. Her clinical work is largely in the area of acute stroke management, hypertension clinics and primary and secondary cardiovascular prevention. Current research interests include:
Novel imaging markers in stroke and small vessel disease using fast field cycling MRI
Using linked datasets to explore management of stroke including service organisation and secondary prevention
Interactions between stroke and other diseases (e.g. cancer)
Memberships and Affiliations
Chair, Clinical Studies Oversight Group
Chair of Scotland A and B Research Ethics Committees
Honorary Deputy Secretary, British and Irish Association of Stroke Physicians
Trustee SHARP (Scottish Heart and Arterial Disease Prevention)
Latest Publications
Impact of Rurality and Geographical Accessibility on Stroke Care and Outcomes
Turner, M., Dennis, M., Barber, M., Macleod, M.StrokeContributions to Journals: ArticlesField-Cycling Imaging yields repeatable brain R1 dispersion measurement at fields strengths below 0.2 Tesla with optimal fitting routine
Senn, N., Ross, P. J., Ayde, R., Mallikourti, V., Krishna, A., James, C., de Vries, C., Broche, L., Waiter, G., Macleod, M.Magnetic Resonance Materials in Physics, Biology and MedicineContributions to Journals: ArticlesTenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial
Muir, K. W., Ford, G. A., Ford, I., Wardlaw, J. M., McConnachie, A., Greenlaw, N., Mair, G., Sprigg, N., Price, C. I., MacLeod, M. J., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L. K., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Lakshmanan, S., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Wiggam, I., Rashed, K., Douglass, C., ATTEST-2 InvestigatorsThe Lancet neurology, vol. 23, no. 11, pp. 1087-1096Contributions to Journals: ArticlesField-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T
Ross, J., Mallikourti, V., Maier, O., Guzman Gutierrez, G., Franko, E., Lurie, D., Broche, L., Macleod, M.Radiology, vol. 312, no. 2, e232972Contributions to Journals: ArticlesAcute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study
Sterling, K., MacLeod, M., Barber, M., Turner, M.Cerebrovascular DiseasesContributions to Journals: Articles
Teaching Responsibilities
Year 5 MBChB OSCE coordinator
Situational Judgement Test lead
Year 1, 3 and 4 Clinical Pharmacology teaching
MSc Clinical Pharmacology: Pharmacovigilance, Medicines Management
Delivers teaching to MSc Cardiovascular and Diabetes, BSc Neurosciences, BSc Genetics
MRCP PACES examiner
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Home-Time Is a Feasible and Valid Stroke Outcome Measure in National Datasets
McDermid, I., Barber, M., Dennis, M., Langhorne, P., Macleod, M. J., McAlpine, C. H., Quinn, T. J.Stroke, vol. 50, no. 5, pp. 1282-1285Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/STROKEAHA.118.023916
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12972/1/Home_Time_210219_Combined_Files.pdf
- [ONLINE] Online-only Data Supplement
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial
Macleod, M., FOCUS Trial CollaborationThe Lancet, vol. 393, no. 10168, pp. 265-274Contributions to Journals: ArticlesThe Association of Atrial Fibrillation and Ischemic Stroke in Patients on Hemodialysis: A Competing Risk Analysis
Findlay, M., MacIsaac, R., Macleod, M. J., Metcalfe, W., Sood, M., Traynor, J. P., Dawson, J., Mark, P.Canadian Journal of Kidney Health and Disease, vol. 6, pp. 1-13Contributions to Journals: ArticlesThe positive predictive value of an ambulance prealert for stroke and transient ischaemic attack
Brown, C. W., Macleod, M. J.European journal of emergency medicine, vol. 25, no. 6, pp. 411-415Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/MEJ.0000000000000475
- [ONLINE] View publication in Scopus
A novel imaging modality (Fast Field-Cycling MRI) identifies ischaemic stroke at ultra-low magnetic field strength
Macleod, M. J., Broche, L., Ross, J., Guzman-Guttierez, G., Lurie, D.International Journal of Stroke, vol. 13, no. 3_Suppl, pp. 62-63Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1177/1747493018801108
Fast Field-Cycling MRI technology: prototype human scanner and first clinical results
Lurie, D. J., Broche, L., Davies, G. R., Guzman Gutierrez, G., Macleod, M., Ross, P. J.Radiological Society of North America Annual MeetingContributions to Conferences: AbstractsRenal replacement modality and stroke risk in end-stage renal disease-a national registry study
Findlay, M., MacIsaac, R., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Dawson, J., Mark, P. B.Nephrology Dialysis Transplantation, vol. 33, no. 9, pp. 1564-1571Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ndt/gfx291
Inequality in Care and Differences in Outcome Following Stroke in People With ESRD
Findlay, M. D., Dawson, J., MacIsaac, R., Jardine, A. G., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Mark, P. B.Kidney International Reports, vol. 3, no. 5, pp. 1064-1076Contributions to Journals: ArticlesTHE MEDICINES ACT 1968 – 20 50 YEARS ON
Macleod, M.Pharmacology Matters, vol. 11, no. 2, pp. 20-21Contributions to Journals: Special IssuesIntravenous Thrombolysis for Ischemic Stroke Patients on Dual Antiplatelets
Tsivgoulis, G., Katsanos, A. H., Mavridis, D., Gdovinova, Z., Karliński, M., Macleod, M. J., Strbian, D., Ahmed, N.Annals of Neurology, vol. 84, no. 1, pp. 89-97Contributions to Journals: ArticlesPractice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study
Langhorne, P., O'Donnell, M. J., Chin, S. L., Zhang, H., Xavier, D., Avezum, A., Mathur, N., Turner, M., Macleod, M. J., Lopez-Jaramillo, P., Damasceno, A., Hankey, G. J., Dans, A. L., Elsayed, A., Mondo, C., Wasay, M., Czlonkowska, A., Weimar, C., Yusufali, A. H., Hussain, F. A., Lisheng, L., Diener, H., Ryglewicz, D., Pogosova, N., Iqbal, R., Diaz, R., Yusoff, K., Oguz, A., Wang, X., Penaherrera, E., Lanas, F., Ogah, O. S., Ogunniyi, A., Iversen, H. K., Malaga, G., Rumboldt, Z., Magazi, D., Nilanont, Y., Rosengren, A., Oveisgharan, S., INTERSTROKE collaborators, Yusuf, S.The Lancet, vol. 391, no. 10134, pp. 2019-2027Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(18)30802-X
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11455/4/Practice_Accepted_Manuscript.pdf
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11455/2/Tables.pdf
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11455/1/Supplementary_Tables.pdf
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11455/3/Practice_Appendix.pdf
The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: Study protocol for a randomised controlled trial
Al-Shahi Salman, R., Dennis, M., Murray, G. D., Innes, K., Drever, J., Dinsmore, L., Williams, C., White, P. M., Whiteley, W., Sandercock, P. A., Sudlow, C., Newby, D. E., Sprigg, N., Werring, D. J., Dennis, M., Sudlow, C., Whiteley, W., Lerpiniere, C., McCormick, K., Perry, J., Parakramawansha, R., Hunter, N., Doubal, F., Paulton, R., O'Brien, R., Burgess, S., Mead, G., Taylor, P., MacLeod, M. J., Maclennan, B., Clarke, R., Taylor, V., Klaasen, K., Crouch, N., Jagpal, B., Furnace, J., Irvine, J., Gow, H., Joyson, A., Nelson, S., Ross, S., Davies, R., Jose, D., Robinson, N., Codd, L., Dodd, A., Moroney, H., Weir, P., Little, V., Gott, V., RESTART collaboratorsTrials, vol. 19, 162Contributions to Journals: ArticlesAbstract WP255: Omega-3 Fatty Acids as a Treatment for Experimental Ischaemic Stroke: A Systematic Review and Meta-analysis
Fulton, L., McCann, S., Macleod, M., Macleod, M., Thies, F.Stroke, vol. 49, AWP255Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1161/str.49.suppl_1.WP255
The Influence of Diabetes on Subtype, Treatment and Outcome in Stroke Patients in Scotland
Sterling, K., Turner, M., Macleod, M.Stroke, vol. 49, WP185Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1161/str.49.suppl_1.WP185
Avoiding unseen obstacles: Subcortical vision is not sufficient to maintain normal obstacle avoidance behaviour during reaching
Ross, A. I., Schenk, T., Billino, J., Macleod, M. J., Hesse, C.Cortex, vol. 98, pp. 177-193Contributions to Journals: ArticlesThe effects of stroke severity on door-to-needle time delays - a retrospective analysis
Ying, L., Turner, M. E., Macleod, M.12th UK Stroke Forum Conference, pp. 8-9Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1177/1747493017732216
Marine-derived n-3 fatty acids therapy for stroke
Alvarez Campano, C. G., Macleod, M. J., Thies, F., Aucott, L., Macleod, M. R.Cochrane Database of Systematic Reviews, vol. 2017, no. 10, pp. 1-12Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/14651858.CD012815
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11235/1/Campano_et_al_2017_.pdf
- [ONLINE] View publication in Scopus
Simple prediction scores predict good and devastating outcomes after stroke more accurately than physicians
Reid, J. M., Dai, D., Delmonte, S., Counsell, C., Phillips, S. J., Macleod, M. J.Age and Ageing, vol. 46, no. 3, pp. 421-426Contributions to Journals: ArticlesReasons for non-recruitment of eligible patients to a randomised controlled trial of secondary prevention after intracerebral haemorrhage: observational study
Maxwell, A. E., Macleod, M., Joyson, A., Johnson, S., Ramadan, H., Bellfield, R., Byrne, A., McGhee, C., Rudd, A., Price, F., Vasileiadis, E., Hewitt, J., Carpenter, M., Needle, A., Valentine, S., Patel, F., Harrington, F., Mudd, P., Emsley, H., Gregary, B., Kane, I., Muir, K., Tiwar, D., Owusu-Agyei, P., Temple, N., Sekaran, L., Ragab, S., England, T., Hedstrom, A., Jones, P., Jones, S., Doherty, M., O McCarron, M., Cohen, D. L., Tysoe, S., Al-Shahi Salman, R.Trials, vol. 18, 162Contributions to Journals: ArticlesThe cost savings of newer oral anticoagulants in atrial fibrillation-related stroke prevention
Masbah, N., Macleod, M. J.International Journal of Clinical Pharmacology and Therapeutics, vol. 55, no. 3, pp. 220-230Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.5414/CP202651
- [ONLINE] View publication in Scopus
Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis
Kellert, L., Hametner, C., Ahmed, N., Rauch, G., MacLeod, M. J., Perini, F., Lees, K. R., Ringleb, P. A.Stroke, vol. 48, no. 7, pp. 1827-1834Contributions to Journals: ArticlesAngina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry
Eisen, A., Bhatt, D. L., Steg, G., Eagle, K. A., Goto, S., Guo, J., Smith, S. C., Ohman, M., Scirica, B. M., Macleod, M., REACH Registry InvestigatorsJournal of the American Heart Association, vol. 5, no. 10, e004080Contributions to Journals: ArticlesStroke: Are care and outcomes better for participants of stroke trials?
Macleod, M. J., Counsell, C. E.Nature Reviews Neurology, vol. 12, no. 9, pp. 498-499Contributions to Journals: Review articlesStroke patients admitted within normal working hours are more likely to achieve process standards and to have better outcomes
Turner, M., Barber, M., Dodds, H., Dennis, M., Langhorne, P., MacLeod, M., Scottish Stroke Care AuditJournal of Neurology, Neurosurgery & Psychiatry, vol. 87, no. 2, pp. 138-143Contributions to Journals: ArticlesDisappearance of the hyperdense MCA sign after stroke thrombolysis: implications for prognosis and early patient selection for clot retrieval
Elofuke, P., Reid, J. M., Rana, A., Macleod, M.Journal of the Royal College of Physicians of Edinburgh, vol. 46, no. 2, pp. 81-86Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.4997/JRCPE.2016.203