Lecturer
- About
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- Email Address
- konstantin.shestopaloff@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I received my PhD in Biostatistics from the University of Toronto, Canada in 2017, specializing in methods for analysis of microbiome and ecological community data. Subsequently, I worked as a biostatistician in arthritis research, conducting analyses of metabolomic and miRNA signature data, and in population health, where I estimated temporal effects of polygenic risk scores in obesity. From 2020 to 2024 I was the Analytics Lead for the IL-17 project group within the Oxford-Novartis collaboration at the Big Data Institute, University of Oxford. I started as a Lecturer in the Medical Statistics Group within the School of Medicine, Medical Sciences and Nutrition in January 2024.
Qualifications
- PhD Biostatistics2017 - University of Toronto
External Memberships
Visiting Researcher, Big Data Institute, University of Oxford, Oxford, United Kingdom
Adjunct Lecturer, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
- Research
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Research Overview
My research focus is on methods development with applications to clinical and biomedical data, particularly methods for addressing sparsity. Some of my previous work includes inference methods for rare species in microbiome data and total species estimators. I have also worked on using nested models for prediction in longitudinal data. My interests in applied statistics focus on biomarker detection using both standard inference methods and machine learning approaches. I've worked extensively in applying data mining for analysing a wide range of omics data and have expertise in statistical genetics.
Research Areas
Applied Health Sciences
Biomedical Sciences
Research Specialisms
- Applied Statistics
- Machine Learning
- Statistical Modelling
- Medical Statistics
- Statistics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Page 1 of 2 Results 1 to 10 of 15
A sequential modeling approach for predicting clinical outcomes with repeated measures
Communications in Statistics - Theory and Methods, vol. 52, no. 20, pp. 7465-7478Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/03610926.2022.2047203
- [ONLINE] View publication in Scopus
Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background
American Journal of Human Genetics, vol. 110, no. 10, pp. 1817-1824Contributions to Journals: ArticlesDCMD:: Distance-based classification using mixture distributions on microbiome data
PLoS Computational Biology , vol. 17, no. 3, e1008799Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pcbi.1008799
Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis
Osteoarthritis and Cartilage, vol. 28, no. 11, pp. 1471-1481Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.joca.2020.07.003
Effect of autotaxin inhibition in a surgically-induced mouse model of osteoarthritis
Osteoarthritis and Cartilage Open, vol. 2, no. 3, 100080Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ocarto.2020.100080
Estimating total species using a weighted combination of expected mixture distribution component counts
Environmental and Ecological Statistics, vol. 27, pp. 447-465Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s10651-020-00452-6
Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation
Stem Cells Translational Medicine, vol. 8, no. 8, pp. 746-757Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/sctm.18-0183
Analyzing differences between microbiome communities using mixture distributions
Statistics in Medicine, vol. 37, no. 27, pp. 4036-4053Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/sim.7896
A classification modeling approach for determining metabolite signatures in osteoarthritis
PloS ONE, vol. 13, no. 6, 0199618Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0199618
Association of host genome with intestinal microbial composition in a large healthy cohort
Nature Genetics, vol. 48, pp. 1413-1417Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/ng.3693