BSc (Hons), MSc, PhD, AFHEA
Lecturer
- About
-
- Email Address
- indrani.mukhopadhya@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
External Memberships
Member of the Microbiology Society
Member of the British Society of Immunology (BSI)
Member of the British Society of Gastroenterology (BSG)
Member of the UK Gut Microbiota for Health Expert Panel
STEM Ambassador
- Research
-
Research Overview
- To underpin the role of the gut microbiota in health and disease.
- Elucidate host-pathogen interactions, pathogenic mechanisms, and immune response of enteric microbes.
- Investigate the mechanism by which gut viruses initiate chronic inflammation in the aetiopathogenesis of inflammatory bowel disease and other gastrointestinal diseases.
- Harness the power of gut microbes as novel therapeutic agents.
Research Areas
Accepting PhDs
I am currently accepting PhDs in Biomedical Sciences.
Please get in touch if you would like to discuss your research ideas further.
Biomedical Sciences
Accepting PhDsResearch Specialisms
- Microbiology
- Virology
- Immunology
- Molecular Biology
- Gastroenterology
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
Knowledge Exchange
- Grampian Liver Research Patient Engagement Event -presentation on Gut Microbiota in liver disease, 2024
- Podcast on Next generation biotherapeutics 2023 Podcast link
- Institute of Medical Sciences, UoA, Doors open day, 2023
- University of Aberdeen May fest 2019, Fantastic Microbes and Where to Find Them.
- Café MED talk on IBD research aimed at a general audience, June 2018
- University of Aberdeen May fest 2017, Man vs Microbes Quiz, aimed to test and enhance public knowledge of microbiology and measures to stay safe from
- Filmed for a short video clip describing my ISSF project (2016), which is now hosted on the ISSF@Aberdeen university website and also on the college YouTube channel
Funding and Grants
- Laboratory start-up fund from Institute of Medical Sciences, UoA - Nov 2022
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Health Protection Scotland grant awarded in Feb 2019 for genotyping of representative rotavirus isolates post introduction of rotavirus vaccine in Scotland – PI
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Wellcome Trust ISSF @ Aberdeen fellowship support award, from October 2015 to March 2016, for the project titled “Role of the enteric virome and its interaction with the bacterial and fungal microbiome in the aetiopathogenesis of Crohn’s disease” – PI
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Health Protection Scotland grant awarded in March 2015 for genotyping of representative rotavirus isolates post introduction of rotavirus vaccine in Scotland – Co-PI
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NHS Grampian Endowment Funding Grant 2014/2015 for the project titled “Elucidating the Role of Non Jejuni/coli-Campylobacter in the Development of Colorectal Cancer Utilising Comparative Genomics to Study their Pathogenetic Potential” – PI
- Teaching
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Courses
Course coordinator
- Year 1 MBChB Immunology Problem-Solving Tutorial (ME2019)
Teaching Responsibilities
Undertake lectures, workshops, practicals, tutorials and assessments for microbiology and immunology courses at the University.
Non-course Teaching Responsibilities
- Supervising BSc Honours and MSc projects
- Personal Tutor for UoA students
- Placement Tutor for MSci students
- Publications
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Butyrate-producing bacteria as probiotic supplement: beneficial effects on metabolism and modulation of behaviour in an obesity mouse model
Beneficial Microbes, pp. 1-16Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1163/18762891-bja00040
Butyrate-producing bacteria as probiotic supplement: beneficial effects on metabolism and modulation of behavior in an obesity mouse model
Working Papers: Preprint Papers- [ONLINE] DOI: https://doi.org/10.1101/2023.11.02.564919
Is HBx protein the X factor in the pathogenesis of IBD?
Gut, vol. 72, no. 10, pp. 1808-1809Contributions to Journals: Comments and DebatesComparison of microbial signatures between paired faecal and rectal biopsy samples from healthy volunteers using next-generation sequencing and culturomics
Microbiome, vol. 10, no. 1, 171Contributions to Journals: ArticlesDietary fibre complexity and its influence on functional groups of the human gut microbiota
Proceedings of the Nutrition Society, vol. 80, no. 4, pp. 386–397Contributions to Journals: ArticlesOral bacterial diversity is inversely correlated with mucosal inflammation
Oral Diseases, vol. 26, no. 7, pp. 1566-1575Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/odi.13420
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15145/1/Hijazi_etal_odi_oralbacteri_a_VOR.pdf
- [ONLINE] View publication in Scopus
In vivo modulation of cervicovaginal drug transporters and tissue distribution by film-released tenofovir and darunavir for topical prevention of HIV-1
Molecular Pharmaceutics, vol. 17, no. 3, pp. 852-864Contributions to Journals: ArticlesFormate cross-feeding and cooperative metabolic interactions revealed by transcriptomics in co-cultures of acetogenic and amylolytic human colonic bacteria
Environmental Microbiology, vol. 21, no. 1, pp. 259-271Contributions to Journals: ArticlesComparative genomics and genome biology of Campylobacter showae
Emerging Microbes and Infections, vol. 8, no. 1, pp. 827-840Contributions to Journals: ArticlesThe gut virome: the ‘missing link’ between gut bacteria and host immunity?
Therapeutic Advances in Gastroenterology, vol. 12, pp. 1-17Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1177/1756284819836620
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12207/1/The_Gut_Virome_Accepted_Manuscript.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Mechanistic insights into the cross-feeding of Ruminococcus gnavus and Ruminococcus bromii on host and dietary carbohydrates
Frontiers in Microbiology, vol. 9, 2558Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3389/fmicb.2018.02558
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11480/1/Mechanistic_Insights_Into_the_Cross_Feeding_of_Ruminococcus_gnavus_and_Ruminococcus_bromii_on_Host_and_Dietary_Carbohydrates.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] Supplementary Material
Review article: the gut microbiome in inflammatory bowel disease-avenues for microbial management
Alimentary Pharmacology & Therapeutics, vol. 47, no. 1, pp. 26-42Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1111/apt.14384
Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii
Environmental Microbiology, vol. 20, pp. 324-336Contributions to Journals: ArticlesComparative genomics of Campylobacter concisus : Analysis of clinical strains reveals genome diversity and pathogenic potential
Emerging Microbes and Infections, vol. 7, 116Contributions to Journals: ArticlesChanging molecular epidemiology of rotavirus infection after introduction of monovalent rotavirus vaccination in Scotland
Vaccine, vol. 35, no. 1, pp. 156-163Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.vaccine.2016.11.028
Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells: Implications for HIV Microbicides
Molecular Pharmaceutics, vol. 13, no. 9, pp. 3334-3340Contributions to Journals: ArticlesSusceptibility to chlorhexidine amongst multidrug-resistant clinical isolates of Staphylococcus epidermidis from bloodstream infections
International Journal of Antimicrobial Agents, vol. 48, no. 1, pp. 86-90Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ijantimicag.2016.04.015
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8641/4/Hijazi_et_al_ms_table_figures_IJAA_v2_clean.pdf
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8641/2/Supplemental_table_1.docx
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8641/1/Supplemental_file_2.docx.xlsx
Drug Transporter Gene Expression in Human Colorectal Tissue and Cell Lines: Modulation with Antiretrovirals for Microbicide Optimization
Journal of Antimicrobial Chemotherapy, vol. 71, no. 2, pp. 372-386Contributions to Journals: ArticlesGenotyping of rotavirus isolates prior to the introduction of the rotavirus vaccine in scotland and early indications of the impact of the vaccine
2nd Digestive-Disorders-Federation Conference, pp. A510-A511Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1136/gutjnl-2015-309861.1116
The fungal microbiota of de-novo paediatric inflammatory bowel disease
Microbes and Infection, vol. 17, no. 4, pp. 304-310Contributions to Journals: ArticlesAssociation of serum antibodies with protection against rotavirus infection and disease in South Indian children
Vaccine, vol. 32, no. Supp 1, pp. A55-A61Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.vaccine.2014.04.077
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8551/1/S0264410X14006161.htm
Rotavirus infections in a community based cohort in Vellore, India.
Vaccine, vol. 32, no. Supp 1, pp. A49-A54Contributions to Journals: ArticlesRole of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?
World Journal of Gastroenterology, vol. 20, no. 5, pp. 1192-1210Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3748/wjg.v20.i5.1192
Diet, the microbiome, and IBD
Inflammatory Bowel Disease Monitor, vol. 14, no. 2, pp. 39-43Contributions to Journals: Literature Reviews- [ONLINE] View publication in Scopus
Rotavirus shedding in symptomatic and asymptomatic children using reverse transcription-quantitative PCR
Journal of Medical Virology, vol. 85, no. 9, pp. 1661-1668Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jmv.23641
A time-resolved immunoassay to measure serum antibodies to the rotavirus VP6 capsid protein
Journal of Virological Methods, vol. 189, no. 1, pp. 228-231Contributions to Journals: ArticlesThe microaerophilic microbiota of de-novo paediatric inflammatory bowel disease: the BISCUIT study
PloS ONE, vol. 8, no. 3, e58825Contributions to Journals: ArticlesMicrobiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis
American journal of gastroenterology, vol. 107, no. 12, pp. 1913-1922Contributions to Journals: ArticlesIBD-what role do Proteobacteria play?
Nature Reviews Gastroenterology & Hepatology, vol. 9, pp. 219-230Contributions to Journals: Literature Reviews- [ONLINE] DOI: https://doi.org/10.1038/nrgastro.2012.14
A comprehensive evaluation of colonic mucosal isolates of Sutterella wadsworthensis from inflammatory bowel disease
PloS ONE, vol. 6, no. 10, e27076Contributions to Journals: Articles- [ONLINE] http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0027076
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0027076
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2168/1/A_Comprehensive_Evaluation_of_Colonic_Mucosal_Isolates_of_Sutterella_wadsworthensis_from_Inflammatory_Bowel_Disease.pdf
The other Helicobacters
Helicobacter, vol. 16 , no. Suppl 1, pp. 70-75Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1523-5378.2011.00884.x
Protective Effect of Natural Rotavirus Infection in an Indian Birth Cohort
The New England Journal of Medicine, vol. 365, no. 4, pp. 337-346Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1056/NEJMoa1006261
Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitis
PloS ONE, vol. 6, no. 6, e21490Contributions to Journals: ArticlesEnterohepatic Helicobacter in ulcerative colitis: potential pathogenic entities?
PloS ONE, vol. 6, no. 2, e17184Contributions to Journals: ArticlesPossible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer
European Journal of Cancer Prevention, vol. 20, no. 1, pp. 54-57Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/CEJ.0b013e328341e320
Innate immune sensors and gastrointestinal bacterial infections
Clinical & Developmental Immunology, vol. 2011, 579650Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1155/2011/579650
Comparison of viral load and duration of virus shedding in symptomatic and asymptomatic neonatal rotavirus infections
Journal of Medical Virology, vol. 82, no. 10, pp. 1803-7Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jmv.21872
Anti-VP6 IgG antibodies against group A and group C rotaviruses in South India
Epidemiology and Infection, vol. 138, no. 3, pp. 442-7Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0950268809990732
Assignment of the group A rotavirus NSP4 gene into genotypes using a hemi-nested multiplex PCR assay: a rapid and reproducible assay for strain surveillance studies
Journal of Medical Microbiology, vol. 58, no. Pt 3, pp. 303-311Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1099/jmm.0.005124-0
Closing the diarrhoea diagnostic gap in Indian children by the application of molecular techniques
Journal of Medical Microbiology, vol. 57, no. Pt 11, pp. 1364-1368Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1099/jmm.0.2008/003319-0
Evidence of intrafamilial transmission of rotavirus in a birth cohort in South India
Journal of Medical Virology, vol. 80, no. 10, pp. 1858-63Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jmv.21263
Polymerase chain reaction in the detection of an 'outbreak' of asymptomatic viral infections in a community birth cohort in south India
Epidemiology and Infection, vol. 136, no. 3, pp. 399-405Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0950268807008709
Molecular characterization of G11P[25] and G3P[3] human rotavirus strains associated with asymptomatic infection in South India
Journal of Medical Virology, vol. 79, no. 11, pp. 1768-74Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jmv.20988
Modification of rotavirus multiplex RT-PCR for the detection of G12 strains based on characterization of emerging G12 rotavirus strains from South India
Journal of Medical Virology, vol. 79, no. 9, pp. 1413-21Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jmv.20872
Human caliciviruses in symptomatic and asymptomatic infections in children in Vellore, South India
Journal of Medical Virology, vol. 79, no. 5, pp. 544-51Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jmv.20862
Neonatal infection with G10P[11] rotavirus did not confer protection against subsequent rotavirus infection in a community cohort in Vellore, South India
The journal of infectious diseases, vol. 195, no. 5, pp. 625-32Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1086/510853
Geographic information systems and genotyping in identification of rotavirus G12 infections in residents of an urban slum with subsequent detection in hospitalized children: emergence of G12 genotype in South India
Journal of Clinical Microbiology, vol. 45, no. 2, pp. 432-7Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/JCM.01710-06
Efficacy and acceptability of chlorine dioxide water disinfectant
Indian journal of medical microbiology, vol. 25, no. 1, pp. 74-5Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.4103/0255-0857.31074
Comparative study of the epidemiology of rotavirus in children from a community-based birth cohort and a hospital in South India
Journal of Clinical Microbiology, vol. 44, no. 7, pp. 2468-74Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/JCM.01882-05
Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India
Journal of Clinical Microbiology, vol. 44, no. 2, pp. 632-4Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/JCM.44.2.632-634.2006
Enteric parasites in patients with diarrhoea presenting to a tertiary care hospital: comparison of Human Immunodeficiency Virus infected and uninfected individuals
The Journal of the Association of Physicians of India, vol. 53, pp. 492Contributions to Journals: Articles