I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
Topical antimicrobials in combination with admission screening and barrier precautions to control endemic methicillin-resistant Staphylococcus aureus in an Intensive Care Unit
Gould, I. M., MacKenzie, F. M., MacLennan, G., Pacitti, D., Watson, E. J., Noble, D.
International Journal of Antimicrobial Agents, vol. 29, no. 5, pp. 536-543
Applying psychological theory to evidence-based clinical practice: identifying factors predictive of taking intra-oral radiographs
Bonetti, D. L., Pitts, N., Eccles, M., Grimshaw, J., Johnston, M., Steen, N., Glidewell, E., Thomas, R. E., MacLennan, G. S., Clarkson, J., Walker, A. E.
Social Science & Medicine, vol. 63, no. 7, pp. 1889-1899
