I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement (BPE)
Lourenco, T., Armstrong, N., N'Dow, J. M. O., Nabi, G., Deverill, M., Pickard, R., Vale, L. D., MacLennan, G. S., Fraser, C. M., McClinton, S., Wong, S., Coutts, A., Mowatt, G., Grant, A. M., BPE Study Group
Unknown Publisher
Books and Reports: Commissioned Reports
Methods of hysterectomy: should women have a say?
Entwistle, V. A., MacLennan, G. S., Skea, Z. C., Bhattacharya, S., Williams, B.
Effectiveness and efficiency of guideline dissemination and implementation strategies
Grimshaw, J. M., Thomas, R. E., MacLennan, G., Fraser, C., Ramsay, C. R., Vale, L., Whitty, P., Eccles, M. P., Matowe, L., Shirran, L., Wensing, M., Dijkstra, R., Donaldson, C.
International Journal of Technology Assessment in Health Care, vol. 21, no. 1
Effectiveness and efficiency of guideline dissemination and implementation strategies
Thomas, R. E., MacLennan, G. S., Fraser, C. M., Ramsay, C. R., Vale, L. D., Whitty, P., Eccles, M. P., Matowe, L., Shirran, E. A., Wensing, M., Dijkstra, R., Donaldson, C.
Health Technology Assessment, vol. 8, no. 6, pp. 1-352
Contributions to Journals: Articles
Effectiveness of strategies to disseminate and implement clinical guidelines for the management of impacted and unerupted third molars in primary dental care, a cluster randomised controlled trial
Bahrami, M., Deery, C., Clarkson, J. E., Pitts, N. B., Johnston, M., Ricketts, I., MacLennan, G., Nugent, Z. J., Tilley, C., Bonetti, D., Ramsay, C.
Primary care guidelines on consultation practices: the effectiveness of computerized versus paper-based versions. A cluster randomized controlled trial among newly qualified primary care physicians
Jousimaa, J., Makela, M., Kunnamo, I., MacLennan, G. S.
International Journal of Technology Assessment in Health Care, vol. 18, no. 3, pp. 586-596
Contributions to Journals: Articles
Attributes of clinical recommendations that influence changes in practice following audit and feedback
Foy, R., MacLennan, G. S., Penney, G., Campbell, M. K., Grol, R.
Journal of Clinical Epidemiology, vol. 55, no. 7, pp. 717-722
