
RNutr
Advanced Research Fellow
- Email Address
- fiona.campbell@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438617
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am a principal investigator based at the Rowett Institute and coordinator of the PGT Human Nutrition MSc programme. My research focuses on advanced glycation end-products (AGEs) in the diet. During food processing AGEs are formed as the result of the Maillard reaction and are absorbed by the body during digestion. To investigate how dietary AGEs, contribute to diet induced conditions such as type 2 diabetes and dementia we are using human intervention studies to test the effects of highly processed foods high in AGEs on sensitive measures of metabolic health and cognition. I am also researching the role of processing methods in improving food quality and the potential for phytochemicals incorporated into processed foods to ameliorate negative health outcomes.
Qualifications
- B.Sc. (Hons.) Biochemistry1985 - University of Aberdeen
- Ph.D. Biomedical Science and Nutrition1998 - University of Aberdeen
Thesis Title: 'Long-chain Fatty Acid Transport by the Human Placenta: The Role of Fatty Acid-Binding Proteins'
External Memberships
Registered Nutritionist with the AfN (RNutr)
Member of the Nutrition Society,
Member of Biochemical Society,
Member of British Society for Proteome Resarch (BSPR).
Latest Publications
Selenium Supplementation in Pregnancy-Maternal and Newborn Outcomes
Biswas, K., McLay, J., Campbell, F. M.Journal of Nutrition and Metabolism, vol. 2022, 4715965Contributions to Journals: ArticlesThe Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction
Sergi, D., Boulestin, H., Campbell, F. M., Williams, L. M.Molecular Nutrition & Food Research, vol. 65, no. 1, 1900934Contributions to Journals: Review articlesAnthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin
Alnajjar, M., Barik, S. K., Bestwick, C., Campbell, F., Cruickshank, M., Farquharson, F., Holtrop, G., Horgan, G., Louis, P., Moar, K., Russell, W. R., Scobbie, L., Hoggard, N.Journal of Functional Foods, vol. 64, 103597Contributions to Journals: ArticlesCinnamon Shows Antidiabetic Properties that Are Species-Specific: Effects on Enzyme Activity Inhibition and Starch Digestion
Hayward, N. J., McDougall, G. J., Farag, S., Allwood, J. W., Austin, C., Campbell, F., Horgan, G., Ranawana, V.Plant Foods for Human Nutrition, vol. 74, no. 4, pp. 544-552Contributions to Journals: ArticlesEarly and reversible changes to the hippocampal proteome in mice on a high-fat diet
McLean, F. H., Campbell, F. M., Sergi, D., Grant, C., Morris, A. C., Hay, E. A., MacKenzie, A., Mayer, C., Langston, R. F., Williams, L. M.Nutrition and Metabolism, vol. 16, no. 1, 57Contributions to Journals: Articles- [ONLINE] https://rdcu.be/bPqy4
- [ONLINE] DOI: https://doi.org/10.1186/s12986-019-0387-y
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12782/1/McLean2019_Article_EarlyAndReversibleChangesToThe_VoR.pdf
- [ONLINE] http://www.ncbi.nlm.nih.gov/pubmed/31462902 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC6708244
- [ONLINE] View publication in Mendeley
Research Overview
A high-fat/sugar diet leads to the formation of Advanced Glycation End products (AGEs) in body tissues. AGEs cause damage and inflammation and are also absorbed from the diet particularly from processed foods. We are interested in how dietary AGEs contribute to diet induced conditions such as type 2 diabetes and cognitive decline.
Current Research
- The role of specific components of the Western diet, namely advanced glycation end products (AGEs), in metabolic health and the development of chronic diseases.
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Key interests include studying the effects of foods containing high levels of AGEs on metabolic health, the potential of phytochemicals to prevent diseases, improving food quality through processing methods, and reformulating processed foods with plant bio-actives.
- Principal investigator for nutrition research studies and leading a Scottish Government (RESAS), funded human intervention study that compares the health benefits of consuming soft fruits. Fruit for Thought: Investigation of nutrition and health properties of new soft fruit crops grown in Scotland | SEFARI., NCT05513404
Past Research
- Principal investigator for nutrition research studies and leading a Scottish Government (RESAS), funded human intervention study that compares the health benefits of consuming soft fruits. Fruit for Thought: Investigation of nutrition and health properties of new soft fruit crops grown in Scotland | SEFARI., NCT05513404 .
Teaching Responsibilities
- Programme lead for the Association of Nutrition (AfN) accredited MSc Human Nutrition programme at the University of Aberdeen (2020- present). Ensure compliance with AfN standards and academic standards set by the University.
- Coordinator of RN5003Foundations of Nutrition course (2020-present)
- Coordinator for on-line course Fundamentals of Nutrition RN5001(2017-present)
- Postgraduate Exam Officer for School of Medicine Medical Sciences and Nutrition
Page 1 of 7 Results 1 to 10 of 64
Selenium Supplementation in Pregnancy-Maternal and Newborn Outcomes
Biswas, K., McLay, J., Campbell, F. M.Journal of Nutrition and Metabolism, vol. 2022, 4715965Contributions to Journals: ArticlesThe Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction
Sergi, D., Boulestin, H., Campbell, F. M., Williams, L. M.Molecular Nutrition & Food Research, vol. 65, no. 1, 1900934Contributions to Journals: Review articlesAnthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin
Alnajjar, M., Barik, S. K., Bestwick, C., Campbell, F., Cruickshank, M., Farquharson, F., Holtrop, G., Horgan, G., Louis, P., Moar, K., Russell, W. R., Scobbie, L., Hoggard, N.Journal of Functional Foods, vol. 64, 103597Contributions to Journals: ArticlesCinnamon Shows Antidiabetic Properties that Are Species-Specific: Effects on Enzyme Activity Inhibition and Starch Digestion
Hayward, N. J., McDougall, G. J., Farag, S., Allwood, J. W., Austin, C., Campbell, F., Horgan, G., Ranawana, V.Plant Foods for Human Nutrition, vol. 74, no. 4, pp. 544-552Contributions to Journals: ArticlesEarly and reversible changes to the hippocampal proteome in mice on a high-fat diet
McLean, F. H., Campbell, F. M., Sergi, D., Grant, C., Morris, A. C., Hay, E. A., MacKenzie, A., Mayer, C., Langston, R. F., Williams, L. M.Nutrition and Metabolism, vol. 16, no. 1, 57Contributions to Journals: Articles- [ONLINE] https://rdcu.be/bPqy4
- [ONLINE] DOI: https://doi.org/10.1186/s12986-019-0387-y
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12782/1/McLean2019_Article_EarlyAndReversibleChangesToThe_VoR.pdf
- [ONLINE] http://www.ncbi.nlm.nih.gov/pubmed/31462902 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC6708244
- [ONLINE] View publication in Mendeley
A high-fat diet induces rapid changes in the mouse hypothalamic proteome
McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A., Mayer, C., Williams, L. M.Nutrition and Metabolism, vol. 16, 26Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s12986-019-0352-9
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12229/1/A_high_fat_diet_induces_rapid_changes_in.pdf
- [ONLINE] Link to version for sharing
- [ONLINE] https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-019-0352-9
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Do advanced glycation end products contribute to saturated fat induced inflammation?
Mazepina, L., Morris, A., Campbell, F. M., Williams, L.Proceedings of the Nutrition Society, vol. 78, no. OCE1, E42Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1017/S0029665119000466
- [ONLINE] View publication in Mendeley
SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice
Sergi, D., Campbell, F. M., Grant, C., Morris, A. C., Bachmair, E., Koch, C., McLean, F. H., Muller, A., Hoggard, N., de Roos, B., Porteiro, B., Boekschoten, M. V., McGillicuddy, F. C., Kahn, D., Nicol, P., Benzler, J., Mayer, C., Drew, J. E., Roche, H. M., Muller, M., Nogueiras, R., DiƩguez, C., Tups, A., Williams, L. M.Genes & Nutrition, vol. 13, 28Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s12263-018-0619-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11568/1/s12263_018_0619_1.pdf
Hippocampal proteomics and primary cell cultures demonstrate proteins key in neuronal plasticity are rapidly changed in rodents on a high-fat diet
McLean, F. H., Campbell, F. M., Langston, R., Williams, L.onference: Society for Neuroscience 2018Contributions to Conferences: AbstractsRapid and reversible impairment of episodic memory by a high-fat diet in mice
McLean, F. H., Grant, C., Morris, A. C., Horgan, G. W., Polanski, A., Allan, K., Campbell, F. M., Langston, R., Williams, L.Scientific Reports, vol. 8, 11976Contributions to Journals: Articles