MSc (Jagiellonian University, Poland); PhD (Jagiellonian University, Poland)
Lecturer
- About
-
- Email Address
- e.krol@abdn.ac.uk
- Telephone Number
- +44 (0)1224 272883
- School/Department
- School of Biological Sciences
- Research
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Research Overview
My research interests focus on whole animal energetics and physiology. This framework provides the common theme that links my interests in the role of energy use during both reproduction and the development of obesity.
Current Research
My doctoral work on the energetics of hedgehogs (Jagiellonian University, Poland) and postdoctoral work on reproduction in laboratory mice (University of Aberdeen, Scotland) and deer mice (University of California, Riverside, USA) have resulted in a novel hypothesis that the limits to sustained energy intake at peak lactation are imposed by the capacity of the animal to dissipate body heat. This hypothesis is currently under further investigation.
My obesity related work focuses on the effects of photoperiod on body mass, food intake, body composition, energy balance and hypothalamic gene expression in the field vole, which provides a new animal model for the investigation of seasonal adiposity at both organism and molecular levels. The major finding of this project is that the photoperiod-induced increase in body mass is associated with the up-regulation of the suppressor of cytokine signalling (SOCS3). This appears to act as a desensitisation mechanism that allows animals to ignore elevated leptin levels generated by increased adiposity, leading to an accumulation of body fat without counter-regulatory mechanisms.
- Publications
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Atlantic salmon (Salmo salar) parr as a model to predict the optimum inclusion of air classified faba bean protein concentrate in feeds for seawater salmon
Aquaculture, vol. 444, pp. 70-78Contributions to Journals: ArticlesFunctional Divergence of Type 2 Deiodinase Paralogs in the Atlantic Salmon
Current Biology, vol. 25, no. 7, pp. 936-941Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.cub.2015.01.074
Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice
Metabolism, vol. 64, no. 2, pp. 305-314Contributions to Journals: ArticlesLimits to sustained energy intake. XXII. Reproductive performance of two selected mouse lines with different thermal conductance
Journal of Experimental Biology, vol. 217, no. 20, pp. 3718-3732Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.103705
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21
Aging Cell, vol. 13, no. 5, pp. 817-827Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/acel.12238
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3721/1/acel12238.pdf
Limits to sustained energy intake. XXI. Effect of exposing the mother, but not her pups, to a cold environment during lactation in mice
Journal of Experimental Biology, vol. 216, no. 23, pp. 4326-4333Contributions to Journals: ArticlesLimits to sustained energy intake. XVI. Body temperature and physical activity of female mice during pregnancy
Journal of Experimental Biology, vol. 216, no. 12, pp. 2328-2338Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.078410
Limits to sustained energy intake. XV. Effects of wheel running on the energy budget during lactation
Journal of Experimental Biology, vol. 216, no. 12, pp. 2316-2327Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.078402
Limits to sustained energy intake. XVII. Lactation performance in MF1 mice is not programmed by fetal number during pregnancy
Journal of Experimental Biology, vol. 216, no. 12, pp. 2339-2348Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.078428
Strong pituitary and hypothalamic responses to photoperiod but not to 6-methoxy-2-benzoxazolinone in female common voles (Microtus arvalis)
General and Comparative Endocrinology, vol. 179, no. 2, pp. 289-295Contributions to Journals: Articles