Dr Delma Childers | People | The University of Aberdeen

Internal Memberships: Aberdeen Fungal Group

Elected Member, University Senate (2020-2024)

Infection and Immunology Research Programme, Institute of Medical Sciences
External Memberships: External Affiliations

Board of Reviewers, Microbiology journal

Elected Eukaryotic Division member, Microbiology Society, 2021-2023

Member of the Young Academy of Scotland, 2020-2025

Public Engagement

Dr. Delma Childers has been a STEM Ambassador since 2015. She has contributed to University of Aberdeen's Door's Open Day at the IMS Building and family activities at May Festival.

Dr. Childers was awarded 'Scientist of the Week' during week 7 in the 2020 Medical Research Zone for 'I'm a Scientist... Stay at Home'. She enjoyed answering student's questions about science and careers during lockdown chats hosted by the 'I'm a Scientist' team.

Dr. Childers also was among the first group of women scientists to take part in Aberdeen's inaugural Soapbox Science event in May 2018.

Latest Publications

Is Metabolic Generalism the Breakfast of Champions for Pathogenic Candida species?
2024 - Accepted/In press
Childers, D., Usher, J.
PLoS Pathogens
Contributions to Journals: Articles
Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.
2024 - Published
Ma, Q., Pradhan, A., Leaves, I., Hickey, E., Roselletti, E., Dambuza, I., Larcombe, D. E., de Assis, L. J., Wilson, D., Erwig, L. P., Netea, M. G., Childers, D. S., Brown, G. D., Gow, N. A. R., Brown, A. J. P.
The Cell Surface, vol. 11, 100128
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.tcsw.2024.100128
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24024/1/Ma_etal_TCS_Impact_secreted_glucanases_VOR.pdf
- [ONLINE] https://www.sciencedirect.com/science/article/pii/S2468233024000100?via%3Dihub
A CO₂ sensing module modulates β-1,3-glucan exposure in Candida albicans.
2024 - Published
Avelar, G. M., Pradhan, A., Ma, Q., Hickey, E., Leaves, I., Liddle, C., Rodriguez Rondon, A. V., Kaune, A., Shaw, S., Maufrais, C., Sertour, N., Bain, J. M., Larcombe, D. E., de Assis, L. J., Netea, M. G., Munro, C. A., Childers, D. S., Erwig, L. P., Brown, G. D., Gow, N. A. R., Bougnoux, M., d'Enfert, C., Brown, A. J. P.
mBio, vol. 15, no. 2, e0189823
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/mbio.01898-23
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22732/2/Avelar_etal_MBIO_A_CO2_Sensing_VoR.pdf
Glucose-enhanced oxidative stress resistance-A protective anticipatory response that enhances the fitness of Candida albicans during systemic infection
2023 - Published
Larcombe, D. E., Bohovych, I. M., Pradhan, A., Ma, Q., Hickey, E., Leaves, I., Cameron, G., Avelar, G. M., de Assis, L. J., Childers, D. S., Bain, J. M., Lagree, K., Mitchell, A. P., Netea, M. G., Erwig, L. P., Gow, N. A. R., Brown, A. J. P.
PLoS Pathogens, vol. 19, no. 7, pp. e1011505
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.ppat.1011505
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/21421/1/Larcombe_etal_PP_Glucose_enhanced_Oxidative_Stress_VOR.pdf
Podcast: Into the Headlines: Strange Sickness
2023 - Published
Grant, L. (ed.), Armstrong, J., Hepburn, W., Childers, D.
Non-textual Forms: Digital or Visual Products
- [ONLINE] https://www.abdn.ac.uk/events/resources/into-the-headlines-2591.php#panel2645
- [ONLINE] Into the Headlines
- [ONLINE] Full transcript of the podcast

View My Publications

Research

Research Overview

My interests are centered around understanding how fungi adapt to their hosts to cause infections. The major focus of my research is to investigate how the antimicrobial-resistant emerging fungal pathogen, Candida glabrata, remodels its surface to inhibit host immune activation and control disease outcomes. This research programme uses cytometric analyses, innate immune interaction assays, and molecular approaches to establish how this important intracellular fungal pathogen is detected by host cells and evades clearance mechanisms.

Another facet of my research builds on my earlier work demonstrating that Saccharomyces cerevisiae clinical isolates are predominantly metabolic generalists that have lost glucose repression. This work is currently exploring how fungal metabolic mechanisms contribute to microbial persistence in their hosts.

My main aim is for my research to lead to a better understanding of fungal antimicrobial resistance, persistence, and pathogenesis. Understanding these facets of fungal biology is the key to improving diagnosis and treatment of serious fungal diseases.

Research Areas

Accepting PhDs

I am currently accepting PhDs in Biomedical Sciences.

Please get in touch if you would like to discuss your research ideas further.

Email Me

Biomedical Sciences

Supervising
Accepting PhDs

View Research Area

Research Specialisms

Microbiology
Molecular Biology
Mycology

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Supervision

My current supervision areas are: Biomedical Sciences.

I am currently accepting expressions of interest from students interested in pursuing a Masters by Research in Medical Sciences degree.

Previous lab members

Eszter Denes, MSc by Research in Medical Sciences

Funding and Grants

Carnegie Trust Research Incentives Grant, March 2020-2021

Royal Society Research Grant, October 2020-2021

Academy of Medical Sciences Springboard Round 6 Award, 2021-2023

Teaching

Courses

Non-course Teaching Responsibilities

Programme Lead

MSc by Research in Medical Sciences

(https://www.abdn.ac.uk/smmsn/postgraduate/research/masters-by-research-in-biomedical-sciences-1228.php)

Other roles

Offering Honours and MSc projects

Personal Tutor

Publications

Page 1 of 1 Results 1 to 31 of 31

Is Metabolic Generalism the Breakfast of Champions for Pathogenic Candida species?
2024 - Accepted/In press
Childers, D., Usher, J.
PLoS Pathogens
Contributions to Journals: Articles
Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.
2024 - Published
Ma, Q., Pradhan, A., Leaves, I., Hickey, E., Roselletti, E., Dambuza, I., Larcombe, D. E., de Assis, L. J., Wilson, D., Erwig, L. P., Netea, M. G., Childers, D. S., Brown, G. D., Gow, N. A. R., Brown, A. J. P.
The Cell Surface, vol. 11, 100128
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.tcsw.2024.100128
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24024/1/Ma_etal_TCS_Impact_secreted_glucanases_VOR.pdf
- [ONLINE] https://www.sciencedirect.com/science/article/pii/S2468233024000100?via%3Dihub
A CO₂ sensing module modulates β-1,3-glucan exposure in Candida albicans.
2024 - Published
Avelar, G. M., Pradhan, A., Ma, Q., Hickey, E., Leaves, I., Liddle, C., Rodriguez Rondon, A. V., Kaune, A., Shaw, S., Maufrais, C., Sertour, N., Bain, J. M., Larcombe, D. E., de Assis, L. J., Netea, M. G., Munro, C. A., Childers, D. S., Erwig, L. P., Brown, G. D., Gow, N. A. R., Bougnoux, M., d'Enfert, C., Brown, A. J. P.
mBio, vol. 15, no. 2, e0189823
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/mbio.01898-23
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22732/2/Avelar_etal_MBIO_A_CO2_Sensing_VoR.pdf
Glucose-enhanced oxidative stress resistance-A protective anticipatory response that enhances the fitness of Candida albicans during systemic infection
2023 - Published
Larcombe, D. E., Bohovych, I. M., Pradhan, A., Ma, Q., Hickey, E., Leaves, I., Cameron, G., Avelar, G. M., de Assis, L. J., Childers, D. S., Bain, J. M., Lagree, K., Mitchell, A. P., Netea, M. G., Erwig, L. P., Gow, N. A. R., Brown, A. J. P.
PLoS Pathogens, vol. 19, no. 7, pp. e1011505
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.ppat.1011505
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/21421/1/Larcombe_etal_PP_Glucose_enhanced_Oxidative_Stress_VOR.pdf
Podcast: Into the Headlines: Strange Sickness
2023 - Published
Grant, L. (ed.), Armstrong, J., Hepburn, W., Childers, D.
Non-textual Forms: Digital or Visual Products
- [ONLINE] https://www.abdn.ac.uk/events/resources/into-the-headlines-2591.php#panel2645
- [ONLINE] Into the Headlines
- [ONLINE] Full transcript of the podcast
The Candida glabrata Parent Strain Trap: How Phenotypic Diversity Affects Metabolic Fitness and Host Interactions
2023 - Published
Usher, J., Ribeiro, G. F., Childers, D. S.
Microbiology spectrum, vol. 11, no. 1, e03724-22
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/spectrum.03724-22
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/20268/1/Usher_etal_MS_The_Candida_Glabrata_VoR.pdf
Nature of b-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation
2022 - Published
de Assis, L. J., Bain, J. M., Liddle, C., Leaves, I., Hacker, C., da Silva, R. P., Yuecel, R., Bebes, A., Stead, D., Childers, D. S., Pradhan, A., Mackenzie, K., Lagree, K., Larcombe, D. E., Ma, Q., Avelar, G. M., Netea, M. G., Erwig, L. P., Mitchell, A. P., Brown, G. D., Gow, N. A., Brown, A. J.
mBio, vol. 13, no. 6, e02605-22
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/mbio.02605-22
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/20404/1/DeAssis_etal_M_Nature_Of_b_1_3_Glucan_Exposing_VoR.pdf
- [ONLINE] View publication in Scopus
Impact of changes at the Candida albicans cell surface upon immunogenicity and colonisation in the gastrointestinal tract
2022 - Published
Avelar, G. M., Dambuza, I. M., Ricci, L., Yuecel, R., Mackenzie, K., Childers, D. S., Bain, J. M., Pradhan, A., Larcombe, D. E., Netea, M. G., Erwig, L. P., Brown, G. D., Duncan, S. H., Gow, N. A. R., Walker, A. W., Brown, A. J. P.
The Cell Surface, vol. 8, 100084
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.tcsw.2022.100084
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/19458/1/Avelar_etal_TCS_Impact_Of_Changes_VoR.pdf
Science in The Media Vs. The Wonderdrug Valley of Death
2021 - Published
Childers, D.
Non-textual Forms: Web Publications and Websites
- [ONLINE] https://researchtheheadlines.org/2021/12/08/science-in-the-media-vs-the-wonderdrug-valley-of-death/
What ‘Omics can tell us about antifungal adaptation
2021 - Published
Ribeiro, G. F., Denes, E., Heaney, H., Childers, D.
FEMS Yeast Research, vol. 21, no. 8, foab070
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1093/femsyr/foab070
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/18412/1/Ribeiro_etal_FEMSYR_What_Omics_Tell_VOR.pdf
Immune cells fold and damage fungal hyphae
2021 - Published
Bain, J., Alonso, F., Childers, D., Walls, C., MacKenzie, K., Pradhan, A., Lewis, L. E., Louw, J., Avelar, G. M., Larcombe, D. E., Netea, M. G., Gow, N. A., Brown, G. D., Erwig, L., Brown, A. J.
PNAS, vol. 118, no. 15, e2020484118
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1073/pnas.2020484118
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16191/1/Bain_etal_PNAS_Immune_Cells_Fold_VoR.pdf
COVID-19 and the Uncertain Future of PhD Research in Scotland
2020 - Published
Childers, D.
Non-textual Forms: Web Publications and Websites
- [ONLINE] https://www.youngacademyofscotland.org.uk/news/covid-19-and-the-uncertain-future-of-phd-research-in-scotland/
Epitope shaving promotes fungal immune evasion
2020 - Published
Childers, D. S., Mol Avelar, G., Bain, J., Pradhan, A., Larcombe, D. E., Netea, M. G., Erwig, L. P., Gow, N. A., Brown, A. J.
mBio, vol. 11, no. 4, e00984-20
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/mBio.00984-20
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14660/1/Childers_et_al_mBio_EpitopeShavingPromotes_VoR.pdf
- [ONLINE] View publication in Scopus
Nine Things Genomics Can Tell Us About Candida auris
2020 - Published
Chybowska, A. D., Childers, D. S., Farrer, R. A.
Frontiers in Genetics, vol. 11, 351
Contributions to Journals: Review articles
- [ONLINE] DOI: https://doi.org/10.3389/fgene.2020.00351
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14371/1/fgene_11_00351.pdf
- [ONLINE] View publication in Scopus
Impact of the Environment upon the Candida albicans Cell Wall and Resultant Effects upon Immune Surveillance
2020 - Published
Childers, D. S., Avelar, G. M., Bain, J. M., Larcombe, D. E., Pradhan, A., Budge, S., Heaney, H., Brown, A. J. P.
The Fungal Cell Wall: An Armour and a Weapon for Human Fungal Pathogens. Latge, J. (ed.). Springer, pp. 297-330, 34 pages
Chapters in Books, Reports and Conference Proceedings: Chapters
- [ONLINE] DOI: https://doi.org/10.1007/82_2019_182
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15420/1/Childers_et_al_CTMI_ImpactOfTheEnvironment_AAM.pdf
- [ONLINE] View publication in Scopus
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
2019 - Published
Pradhan, A., Avelar, G. M., Bain, J. M., Childers, D., Pelletier, C., Larcombe, D. E., Shekhova, E., Netea, M. G., Brown, G. D., Erwig, L., Gow, N. A. R., Brown, A. J. P.
Nature Communications, vol. 10, 5315
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1038/s41467-019-13298-9
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13428/1/Pradhan_etal_NatComm_Non_canonical_signalling_VOR.pdf
Growth, Viability, and Death of Planktonic and Biofilm Sphingomonas desiccabilis in Simulated Martian Brines
2019 - Published
Stevens, A. H., Childers, D., Fox-Powell, M., Nicholson, N., Jhoti, E., Cockell, C. S.
Astrobiology, vol. 19, no. 1, pp. 87-98
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1089/ast.2018.1840
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15718/1/ast.2018.1840.pdf
- [ONLINE] View publication in Scopus
Hypoxia Promotes Immune Evasion by Triggering β-glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling
2018 - Published
Pradhan, A., Avelar, G. M., Bain, J. M., Childers, D. S., Larcombe, D. E., Netea, M. G., Shekhova, E., Munro, C. A., Brown, G. D., Erwig, L. P., Gow, N. A. R., Brown, A. J. P.
mBio, vol. 9, e01318-18
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/mBio.01318-18
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11411/1/Hypoxia_Promotes_Immune_Evasion_by_Triggering_Glucan_Masking_on_the_Candida_albicans_Cell_Surface_via_Mitochondrial_and_cAMP_Protein_Kinase_A_Signaling.pdf
Lactate signalling regulates fungal β-glucan masking and immune evasion
2016 - Published
Ballou, E., M. Avelar, G., Childers, D. S., Mackie, J., Bain, J. M., Wagener, J., Kastora, S. L., Panea, M. D., Hardison, S. E., Walker, L., Erwig, L. P., Munro, C. A., Gow, N. A. R., Brown, G. D., MacCallum, D. M., Brown, A. J. P.
Nature Microbiology, vol. 2, 16238
Contributions to Journals: Articles
- [ONLINE] https://eorder.sheridan.com/3_0/app/orders/6371/article.php
- [ONLINE] DOI: https://doi.org/10.1038/nmicrobiol.2016.238
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8797/1/Nature_Microbiology_Article_16238.pdf
Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections
2016 - Published
MacKie, J., Szabo, E. K., Urgast, D. S., Ballou, E. R., Childers, D. S., MacCallum, D. M., Feldmann, J., Brown, A. J. P.
PloS ONE, vol. 11, no. 6, e0158683
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0158683
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/6197/1/2016_Joanna_Copper_poisoning.pdf
The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence
2016 - Published
Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M., Brown, A. J. P.
PLoS Pathogens, vol. 12, no. 4, 1005566
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.ppat.1005566
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5870/1/journal.ppat.1005566.PDF
Filament condition-specific response elements control the expression of NRG1 and UME6, key transcriptional regulators of morphology and virulence in Candida albicans
2015 - Published
Childers, D. S., Kadosh, D.
PloS ONE, vol. 10, no. 3, e0122775
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0122775
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12828/1/Childers_etal_pone_Filament_Condition_Specific_VOR.PDF
New Clox Systems for rapid and efficient gene disruption in Candida albicans
2014 - Published
Shahana, S., Childers, D. S., Ballou, E. R., Bohovych, I., Odds, F. C., Gow, N. A. R., Brown, A. J. P.
PloS ONE, vol. 9, no. 6, e100390
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0100390
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3786/1/journal.pone.0100390.pdf
A 5′ UTR-mediated Translational Efficiency Mechanism Inhibits the Candida albicans Morphological Transition
2014 - Published
Childers, D. S., Mundodi, V., Banerjee, M., Kadosh, D.
Molecular Microbiology, vol. 92, no. 3, pp. 570-585
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1111/mmi.12576
Conflicting interests in the pathogen-host tug of war: fungal micronutrient scavenging versus mammalian nutritional immunity
2014 - Published
Potrykus, J., Ballou, E. R., Childers, D. S., Brown, A. J. P.
PLoS Pathogens, vol. 10, no. 3, e1003910
Contributions to Journals: Literature Reviews
- [ONLINE] DOI: https://doi.org/10.1371/journal.ppat.1003910
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3631/1/Confliciting_interests.pdf
New Clox systems for rapid and efficient gene disruption in Candida albicans
2014 - Published
Shahana, S., Childers, D. S., Ballou, E. R., Bohovych, I., Odds, F. C., Gow, N. A. R., Brown, A. J. P.
American society of Microbiology
Contributions to Conferences: Abstracts
New Clox systems for rapid and efficient gene disruption in Candida albicans
2014 - Published
Shahana, S., Childers, D. S., Ballou, E. R., Bohovych, I., Odds, F. C., Gow, N. A. R., Brown, A. J. P.
American society of Microbiology
Contributions to Conferences: Posters
Stress adaptation in a pathogenic fungus
2014 - Published
Brown, A. J. P., Budge, S., Kaloriti, D., Tillmann, A., Jacobsen, M. D., Yin, Z., Ene, I. V., Bohovych, I., Sandai, D., Kastora, S., Potrykus, J., Ballou, E. R., Childers, D. S., Shahana, S., Leach, M. D.
Journal of Experimental Biology, vol. 217, no. 1, pp. 144-155
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1242/jeb.088930
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5474/1/144.full.pdf
Comparative evolution of morphological regulatory functions in Candida species
2013 - Published
Lackey, E., Vipulanandan, G., Childers, D. S., Kadosh, D.
Eukaryotic Cell, vol. 12, no. 10, pp. 1356-1368
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/EC.00164-13
Coevolution of morphology and virulence in Candida species
2011 - Published
Childers, D. S. T., Carlisle, P. L., Kadosh, D.
Eukaryotic Cell, vol. 10, no. 9, pp. 1173-1182
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1128/EC.05085-11
UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence
2008 - Published
Banerjee, M., Thompson, D. S., Lazzell, A., Carlisle, P. L., Pierce, C., Monteagudo, C., López-Ribot, J. L., Kadosh, D.
Molecular Biology of the Cell, vol. 19, no. 4, pp. 1354-1365
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1091/mbc.E07-11-1110
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3158/1/banerjee_et_al_2008.pdf

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Chapters in Books, Reports and Conference Proceedings

Chapters (1)

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Abstracts (1)

Posters (1)

Contributions to Journals

Articles (23)

Literature Reviews (1)

Review articles (1)

Non-textual Forms

Digital or Visual Products (1)

Web Publications and Websites (2)

Update

Biography

Memberships and Affiliations

Latest Publications

Is Metabolic Generalism the Breakfast of Champions for Pathogenic Candida species?

Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.

A CO2 sensing module modulates β-1,3-glucan exposure in Candida albicans.

Glucose-enhanced oxidative stress resistance-A protective anticipatory response that enhances the fitness of Candida albicans during systemic infection

Podcast: Into the Headlines: Strange Sickness

Research Overview

Research Areas

Accepting PhDs

Biomedical Sciences

Research Specialisms

Supervision

Funding and Grants

Courses

Non-course Teaching Responsibilities

Is Metabolic Generalism the Breakfast of Champions for Pathogenic Candida species?

Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.

A CO2 sensing module modulates β-1,3-glucan exposure in Candida albicans.

Glucose-enhanced oxidative stress resistance-A protective anticipatory response that enhances the fitness of Candida albicans during systemic infection

Podcast: Into the Headlines: Strange Sickness

The Candida glabrata Parent Strain Trap: How Phenotypic Diversity Affects Metabolic Fitness and Host Interactions

Nature of b-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation

Impact of changes at the Candida albicans cell surface upon immunogenicity and colonisation in the gastrointestinal tract

Science in The Media Vs. The Wonderdrug Valley of Death

What ‘Omics can tell us about antifungal adaptation

Immune cells fold and damage fungal hyphae

COVID-19 and the Uncertain Future of PhD Research in Scotland

Epitope shaving promotes fungal immune evasion

Nine Things Genomics Can Tell Us About Candida auris

Impact of the Environment upon the Candida albicans Cell Wall and Resultant Effects upon Immune Surveillance

Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion

Growth, Viability, and Death of Planktonic and Biofilm Sphingomonas desiccabilis in Simulated Martian Brines

Hypoxia Promotes Immune Evasion by Triggering β-glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

Lactate signalling regulates fungal β-glucan masking and immune evasion

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence

Filament condition-specific response elements control the expression of NRG1 and UME6, key transcriptional regulators of morphology and virulence in Candida albicans

New Clox Systems for rapid and efficient gene disruption in Candida albicans

A 5′ UTR-mediated Translational Efficiency Mechanism Inhibits the Candida albicans Morphological Transition

Conflicting interests in the pathogen-host tug of war: fungal micronutrient scavenging versus mammalian nutritional immunity

New Clox systems for rapid and efficient gene disruption in Candida albicans

New Clox systems for rapid and efficient gene disruption in Candida albicans

Stress adaptation in a pathogenic fungus

Comparative evolution of morphological regulatory functions in Candida species

Coevolution of morphology and virulence in Candida species

UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence