Advanced Research Fellow
- About
-
- Email Address
- c.s.whyte@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437897
- Office Address
Lab 1.33 Office 3.47:6
Institute of Medical Sciences
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am an Advanced Research Fellow at the Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Science. I obtained my PhD in Medical Sciences at Rowett Research Institute of Nutrition and Health through the University of Aberdeen. My research to date has focused on cellular regulation of fibrinolysis with a particular interest in the role of platelets in directing this process. I have also investigated fibrinolytic dysregulation in disease situations including COVID-19, DVT and stroke. I have recently started on a Transition to Independence Fellowship funded by Friends of Anchor to investigate dysregulated fibrinolysis in cancer associated thrombosis.
Qualifications
- PhD Medical Sciences2009 - University of Aberdeen
Memberships and Affiliations
- Internal Memberships
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Nvision Researcher Development Network Committee
Postdoctoral Research Committee - Institute of Medical Sciences Representative
Institute of Medical Sciences Health and Safety Committee - ECR Representative
- External Memberships
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British Society for Haemostasis and Thrombosis Committee
Council Member (Class of 2027) - International Society for Fibrinolysis and Proteolysis
Latest Publications
Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation
Blood Advances, 2024012979Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/bloodadvances.2024012979
Fibrinogenolysis and fibrinolysis in Vaccine-induced Immune Thrombocytopenia and Thrombosis (VITT)
Journal of Thrombosis and Haemostasis, vol. 21, no. 12, pp. 3589-3596Contributions to Journals: ArticlesNovel therapeutics and emerging technology in haemostasis and thrombosis: highlights from the British society for haemostasis and thrombosis annual meeting
Frontiers in cardiovascular medicine, vol. 10, 1225243.Contributions to Journals: ArticlesPlatelet factor XIII-A regulates platelet function and promotes clot retraction and stability
Research and Practice in Thrombosis and Haemostasis, vol. 7, no. 5, 100200Contributions to Journals: ArticlesAll tangled up: interactions of the fibrinolytic and innate immune systems
Frontiers in Medicine, vol. 10, 1212201Contributions to Journals: Articles
Prizes and Awards
D. Collen Young Investigator Award runner up 2023
D. Collen Young Investigator Award runner up 2018
- Research
-
Supervision
Supervisees
- MR ANUJ NARWAL
- MR KIERAN POCKNELL
- MR STEVEN HUMPHREYS
- Publications
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Page 2 of 3 Results 11 to 20 of 26
Factor XIII-A: An Indispensable “Factor” in Haemostasis and Wound Healing
International Journal of Molecular Sciences, vol. 22, no. 6, 3055Contributions to Journals: ArticlesuPA-mediated plasminogen activation is enhanced by polyphosphate
Haematologica, vol. 106, no. 2, pp. 522-531Contributions to Journals: ArticlesExposure of plasminogen and a novel plasminogen receptor, Plg-RKT, on activated human and murine platelets
Blood, vol. 137, no. 2, pp. 248–257Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood.2020007263
- [ONLINE] View publication in Scopus
Physiology of haemostasis: Plasmin-antiplasmin system
Trauma Induced Coagulopathy. Moore, H., Neal, M., Moore, E. (eds.). Springer, pp. 53-74, 22 pagesChapters in Books, Reports and Conference Proceedings: Chapters- [ONLINE] DOI: https://doi.org/10.1007/978-3-030-53606-0_5
- [ONLINE] View publication in Scopus
A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency
Journal of Thrombosis and Haemostasis, vol. 18, no. 9, pp. 2209-2214Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/jth.14990
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15105/1/Westbury_etal_jth_New_pedigree_VOR.pdf
- [ONLINE] View publication in Scopus
Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID‐19
Journal of Thrombosis and Haemostasis, vol. 18, no. 7, pp. 1548-1555Contributions to Journals: ArticlesFunctional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation
Haematologica, vol. 105, no. 5Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3324/haematol.2019.230367
- [ONLINE] Open Access license
Platelet-Mediated Modulation of Fibrinolysis
Seminars in Thrombosis and Hemostasis, vol. 43, no. 2, pp. 115-128Contributions to Journals: Review articlesPolyphosphate delays fibrin polymerisation and alters the mechanical properties of the fibrin network
Thrombosis and Haemostasis, vol. 116, no. 5, pp. 897-903Contributions to Journals: ArticlesAltered fibrinolysis in autosomal dominant thrombomodulin-associated coagulopathy
Blood, vol. 128, no. 14, pp. 1879-1883Contributions to Journals: Articles