Dr Alexander Ross

Dr Alexander Ross
Dr Alexander Ross
Dr Alexander Ross

Advanced Research Fellow

About
Research

Research Overview

In our research we are investigating how different foods and their constituents inform fullness and satiety to the brain. The objectives are to identify how cells of the gut and liver respond differently to different nutrients, and also how these nutrients may differentially affect metabolism to promote improved health. We are also interested in how diet-induced differences in the gut microbiome may alter host metabolism and health. The research results should provide evidence which, after validation in human trials, may be released as advice to the general public, or as product formulation advice to the food or drug industry aimed at healthy weight management. 

We use molecular biology and biochemical approaches including Next Generation Sequencing, Real-time PCR, in situ hybridization and Western blotting to identify target genes and exploit novel in vivo agonist/antagonist or antibody delivery in techniques aimed at addressing functional responses.

 

Research team

Prof Alexandra Johnstone

Claire Fyfe - Research Assistant

Gail Hepseed - Research assistant

 

 

Funding and Grants

Biotechnology and Biological Science Research Council (BBSRC) grant number BB/K001043/1 entitled: Inflammatory signals regulate neuroendocrine control of growth and energy balance through re-modelling of mammalian hypothalamus.

Publications

Page 5 of 6 Results 41 to 50 of 51

  • A novel interaction between inhibitory melatonin receptors and protein kinase C-dependent signal transduction in ovine pars tuberalis cells

    Ross, A., Webster, C. A., Thompson, M., Barrett, P., Morgan, P. J.
    Endocrinology, vol. 139, no. 4, pp. 1723-1730
    Contributions to Journals: Articles
  • Mel 1a melatonin receptor expression is regulated by protein kinase C and an additional pathway addressed by the protein kinase C inhibitor Ro 31-8220 in ovine pars tuberalis cells

    Barrett, P., Davidson, G., Hazlerigg, D. G., Morris, A., Ross, A., Morgan, P. J.
    Endocrinology, vol. 139, no. 1, pp. 163-171
    Contributions to Journals: Articles
  • The use of DNA fingerprinting to assess monozygotic twinning in Meishan and Landrace x Large White pigs

    Ashworth, C. J., Ross, A., Barrett, P.
    Reproduction, Fertility and Development, vol. 10, no. 6, pp. 487-490
    Contributions to Journals: Articles
  • Melatonin suppresses the induction of AP-1 transcription factor components in the pars tuberalis of the pituitary

    Ross, A., Barrett, P., Mercer, J., Morgan, P. J.
    Molecular and Cellular Endocrinology, vol. 123, no. 1, pp. 71-80
    Contributions to Journals: Articles
  • The ovine pars tuberalis secretes a factor(s) that regulates gene expression in both lactotropic and nonlactotropic pituitary cells

    Morgan, P. J., Webster, C. A., Mercer, J., Ross, A., Hazlerigg, D. G., MacLean, A., Barrett, P.
    Endocrinology, vol. 137, no. 9, pp. 4018-4026
    Contributions to Journals: Articles
  • Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP-dependent and cyclic AMP-independent mechanisms

    McNulty, S., Ross, A. W., Shiu, K. Y., Morgan, P. J., Hastings, M. H.
    Journal of Neuroendocrinology, vol. 8, no. 8, pp. 635-645
    Contributions to Journals: Articles
  • Interrelationships of protein and oestradiol secretion by conceptuses and endometrium from Meishan pigs on days 11-15 of pregnancy

    Ashworth, C. J., Ross, A. W., Flint, A. P. F.
    Animal Reproduction Science, vol. 43, no. 2-3, pp. 123-135
    Contributions to Journals: Articles
  • Melatonin Regulates the Phosphorylation of CREB in Ovine pars Tuberalis

    MCNULTY, S., Ross, A., Barrett, P., HASTINGS, M. H., Morgan, P. J.
    Journal of Neuroendocrinology, vol. 6, no. 5, pp. 523-532
    Contributions to Journals: Articles
  • COMPARISONS BETWEEN PERIPHERAL PROGESTERONE CONCENTRATIONS IN CYCLIC AND PREGNANT LANDRACE X LARGE WHITE AND MEISHAN GILTS

    ASHWORTH, C. J., ROSS, A. W., HALEY, C. S.
    Reproduction, Fertility and Development, vol. 6, no. 6, pp. 777-782
    Contributions to Journals: Articles
  • NAD turnover and utilisation of metabolites for RNA synthesis in a reaction sensing the redox state of the cytochrome b6f complex in isolated chloroplasts

    Pearson, C. K., Wilson, S. B., Schaffer, R., Ross, A. W.
    European Journal of Biochemistry, vol. 218, no. 2, pp. 397-404
    Contributions to Journals: Articles
Show 10 | 25 | 50 | 100 results per page