Factors Affecting Variations in Campylobacter Disease Rates in Scotland

Factors Affecting Variations in Campylobacter Disease Rates in Scotland

Funded by Food Standards Scotland – Project No: FS101106

Previous work has established that there is an apparent lower incidence of reported Campylobacter infections in deprived populations. However this is not observed in hospitalised cases. This project investigates the origin of these differences between deprived and prosperous populations in four ways. First, investigating potential biases at three different levels of the reporting pyramid: the community level, the GP level and the reported case level. Second analysing retrospective and prospective case and hospitalisation discharge data to determine whether the reported variation in disease still occurs. Third, carrying out a case control study to identify the sources of human campylobacteriosis and fourth performing a case-case analysis to determine differences in risk factors for deprived and less deprived (affluent) populations. This work will provide the scientific evidence to inform FSA policy on dealing with Campylobacter risk in the Scottish population.

 

Objectives

  • Collect retrospective and prospective reported case data to identify if disease incidence and risk factors change by level of deprivation;
  • Collect retrospective and prospective hospital discharge data to identify if hospitalisation rates and risk factors change by level of deprivation;
  • Collect and analyse case-control and case-case data (to be acquired in least and most deprived case and control cohorts) to identify risk factors that are specific to deprivation groups;
  • Investigate potential reporting biases by level of deprivation;
    • Estimation of reporting biases at the community level
    • Estimation of reporting biases at the GP level
    • Estimation of reporting biases at the reported case level

Ethics

Approvals from the following bodies were obtained to conduct the current research study:

  • NRES Committees - North of Scotland –REC Reference -15/NS/0072
  • Public Benefit and Privacy Panel – Reference – 1516-0240

Key Partners

  • CampylobacterEpidemiology research team at NHS Tayside
  • NHS Boards: Greater Glasgow & Clyde, Grampian, Lanarkshire, Lothian, Fife, Forth Valley and Tayside
  • NHS Medical Microbiological Diagnosis Laboratories across Scotland

 

Contacts

Medical

Dr. Christopher McGuigan
Consultant in Public Health Medicine
NHS Fife
Cameron Hospital, Cameron Bridge
Leven, Fife, KY8 5RG

Email: chris.mcguigan@nhs.net
Work Telephone 01592 226912


Professor Norval StrachanPrincipal Investigator

Professor Norval Strachan
School Natural and Computing Sciences
St. Machar Drive,
Cruickshank Building,
Aberdeen, AB24 3UU

Email:  n.strachan@abdn.ac.uk
Telephone 01224 272699


Principal Investigator

Professor  Ken Forbes
University of Aberdeen
School of Medicine and Dentistry
0:015 Polwarth Building, Foresterhill
Aberdeen, AB25 2ZD, UK

Email: k.forbes@abdn.ac.uk
Telephone: 01224 437023


Dr. Ovidiu RotariuResearch Fellow

Dr. Ovidiu Rotariu
University of Aberdeen
School Natural and Computing Sciences/Biological Sciences
Cruickshank Building
Aberdeen, AB24 3UU

Email: ovidiu.rotariu@abdn.ac.uk
Telephone: 01224  272700

 

Partners

University of Aberdeen NHS Tayside Food Standards Scotland