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The School of Natural and Computing Sciences

Selected publications

Selected publications
  1. Wu, L., Maglangit, F. & Deng, H., Current Opinion in Chemical Biology. 2020. 55, 119-126.
  2. Zhou Y., Lin X., Xu C., Shen Y., Wang S.-P., Liao H., Li L., Deng H. Hou-Wen Lin. Cell Chem. Biol., 2019, 26, 737-744.
  3. Liu, Y., Su, L., Fang, Q., Tabudravu, J., Yang, X., Rickaby, K., Trembleau, L., Kyeremeh, K., Deng, Z., Deng, H. & Yu, Y., J. Org Chem. 2019, 84, 16323-16328.
  4. X Ma L., Bartholome A., Tong M.H.; Yu Y., Shepherd T., Kyeremeh K., Deng H.; O’Hagan D. Chem. Sci., 2015, 6 (2), 1414-1419.
  5. Huang S., Tabudravu J., Elsayed S. S., Travert J., Peace D., Tong M. H., Kyeremeh K., Trembleau L., Ebel R., Jaspars M., Yu Y., Deng H. Angew Chemie Int. Ed. 2015, 54(43), 12697-12701.
  6. Huang S., Elsayed S. S., Tabudravu J., Rateb M. E., Gyampoh R., Kyeremeh K., Ebel R., Jaspars M., Yu Y., Deng H. Chem. & Biol., 2015, 22, 1-10.
  7. O’Hagan D. and Deng H. Chem. Rev., 2015, 115(2), 634-649.
  8. Ceide, S., Trembleau, L., Haberhauer, G., Somogyi, L., Bartfai, T., Rebek Jnr, J., 'Synthesis of galmic: A nonpeptide galanin receptor agonist', Proc. Natl. Acad. Sci. USA 2004, 101, 16727-16732.
  9. Meneses, C, Nicoll, S. & Trembleau, L., 'Multigram-scale synthesis of short peptides via a simplified repetitive solution-phase procedure', J. Org. Chem. 2010, 75, 564-569.
  10. Alexandru-Crivac C., Umeobika C., Leikoski N., Jokela J., Rickaby K., Grilo A., Sjo P., Plowright A., Idress M., Siebs E., Nneoyi-Egbe A., Wahlsten M., Sivonen K., Jaspars M., Trembleau L., Fewer, D., Houssen Ibrahim W. 2017, 'Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants', Chem. Comm. 2017, 53, 10656-10659.
  11. Parajuli A., Kwak D., Dalponte L., Leikoski N., Galica T., Umeobika C., Trembleau L., Bent A., Sivonen K., Wahlsten M., Wang H., Rizzi E., De Bellis G., Naismith J., Jaspars M., Liu X., Houssen W. & Fewer, D., 'A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway', Angew. Chemie 2016, 128, 3660-3663.
  12. Cristina N. Alexandru-Crivac, Luca Dalponte, Wael E. Houssen, Mohannad Idress, Marcel Jaspars, Kirstie A. Rickaby and Laurent Trembleau, Cyclic Peptides – A Look to the Future. in J. Koehnke, J. Naismith & W. A. van der Donk (eds), Cyclic Peptides: From Bioorganic Synthesis to Applications. Royal Society of Chemistry (Great Britain), UK, 2017, 340-373.
  13. Badarau E., Reddy H. V., Loudet A., Trembleau L., Claerhout S., Pair E. Massip S., Breton P., Lesur B., Goldstein S., Fourquez J.-M., Henlin J.-M., Ghosez L. “Productive Syntheses of Privileged Scaffolds Inspired by the Recognition of a Diels-Alder Pattern Common to three Classes of Natural Products” [published online ahead of print, 2020 May 19]. Chem. Eur. J. 2020;10.1002/chem.202002372. doi:10.1002/chem.202002372
  14. Bartfai, T., Conde Ceide S., Haberhauer G., Laszlo S., Rebek J. J., Trembleau L., “Galanin agonists” 2006, patent No. WO2006004841A3.
  15. Materials and methods for medical imaging, Smith T. A. D., Trembleau, L., McLaughlin A. & Simpson M., 2010, IPC No. WO2009056837, Patent No. GB2467494 (A)
  16. Greig I, Baillie G., Abdelrahman M., Trembleau L. & Ross R., 'Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators', Bioorg. Med. Chem. Lett. 2016, 26, 4403-4407.
  17. Abdelrahman M., PhD Thesis, University of Aberdeen, 2010.
  18. Trembleau L. Simpson M., Cheyne R., Escofet I, Appleyard M., Murray K., Sharp S., Thompson A., Smith, T. 'Development of 18F-fluorinatable dendrons and their application to cancer cell targeting', New J. Chem., 2011, 2496-2502.
  19. Idress M., Milne B., Thompson G., Trembleau, L., Jaspars, M., Houssen W., 'Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide', Molecules 2020, 922.
  20. Trembleau, LAC & Rebek Jnr, J 2003, 'Helical Conformation of Alkanes in a Hydrophobic Cavitand', Science, vol. 301, pp. 1219-1220.
  21. Trembleau, L, Hof, F. Ulrich, E & Rebek Jnr, J 2003, 'Acetylcholine Recognition by a Deep, Biomimetic Pocket', Angewandte Chemie International Edition, vol. 42, pp. 3150-3153.
  22. Trembleau L., Smith T. & Abdelrahman M., 'Receptor conformational change induces fluoride binding despite competitive water binding', Chem. Comm. 2013, 49, 5850-5852.
  23. Trembleau L. 48th Scottish Regional Organic Division Meeting, St Andrews (Scotland), 9 January 2020. “Mechanism of the Direct Amidation Reaction”.