Non Hodgkins Lymphoma

• Non-Hodgkin's lymphoma is a heterogeneous group of diseases.
• The section on management will only describe treatement of the two commonest lymphomas, diffuse large B-cell lymphoma and follicular lymphoma.

Diffuse large B-cell lymphomas is a useful example for management of high grade lymphomas [4]. General principles:

• Stage 1 and 2 disease are treated with anthracylin-based chemotherapy e.g. CHOP, followed by involved field radiation therapy.
• Stage 3 and 4 is treated solely with chemotherapy, anthracyclin based e.g. CHOP as well as Rituximab.
• Further chemotherapy is given to patients who fail on initial treatment.
• Salavage treatment, for patients who relapse or who show no initial response, is with high dose chemotherapy with autologous stem cell rescue.