Differential Diagnosis of Facial Weakness

The key is to work out whether facial weakness is:

  1. Truly unilateral?
    • Bilateral facial weakness could suggest another diagnosis e.g. Myasthenia gravis or Guillain Barre syndrome
  2. Upper or lower motor neuron (see next slide)?
  3. Additional features would suggest an alternative diagnosis i.e. other cranial nerve problems (Bell's palsy should just involve CN VII) OR symptoms / signs in the limbs that could suggest a more significant CNS problem i.e. brainstem stroke, tumour or demyelinating lesion OR no signs of a rash which might suggest an alternative cause.