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Other unwanted effects

Hypersensitivity reactions Pulmonary oedema, photosensitivity and skin rashes.
Hyperglycaemia This may result from the opening of K+ATP channels in B-cells of the pancreas, from hypokalaemia and from reduced tissue sensitivity to insulin
Erectile dysfunction This occurs in about 10% of middle-aged males treated with high doses of thiazides. The impotence is reversible on withdrawal of the thiazide.