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Antagonists at the AT1 receptor (sartans)
Use of sartans in the treatment of essential hypertension:
May be used alone or in combination with a different class of antihypertensive agent.
Since they do not inhibit the metabolism of bradykinin, they provide a useful alternative in patients who cannot tolerate the dry cough associated with the use of ACE inhibitors.
Contra-indicated in pregnancy and breast feeding.
Caution should be exercised when prescribing sartans for patients with stenosis of a renal artery...
