A. Correct. Clrenal = fe.Cltotal Values are 12.5 (amoxicillin); 1.24 (propranolol); <0.2 (ciclosporin)
B. Incorrect.
C. Incorrect.
Which drug has the highest renal clearance?
Select one option from the answers below
Characeristic | amoxicillin | propranolol | ciclosporin |
---|---|---|---|
Usual dose (mg) | 250 | 80 | 350 |
Vd (L) | 29 | 360 | 245 |
Fraction unbound (fu) | 0.82 | 0.1 | 0.06 |
Half-life (h) | 0.9 | 4 | 8 |
Fraction excreted unchanged (fe) | 0.56 | 0.02 | <0.01 |