Case study 2 - Question 1

Which drug has the lowest total clearance?

Select one option from the answers below

Amoxicillin    
Propranolol    
Ciclosporin     green tick


Characeristicamoxicillinpropranololciclosporin
Usual dose (mg)25080350
Vd (L)29360245
Fraction unbound (fu)0.820.10.06
Half-life (h)0.948
Fraction excreted unchanged (fe)0.560.02<0.01