Learning Objectives

By the end of this session you will be able to:

  • Describe the typical concentration-time curve for a drug with first-order kinetics

  • Explain the importance of zero-order (saturation) kinetics

  • Define clearance and half-life

  • Define bioavailability

  • Prerequisites

    Before commencing this session you should have:

  • An understanding of basic physiological concepts, including cells and membranes, body compartments, lipid and water solubility, the functions of the liver and kidney, and the cardiovascular system

  • Completed the related Prescribe sessions

    Principles of Clinical Pharmacology/Pharmacokinetics/Pharmacokinetics I - Introduction to Pharmacokinetics

    Principles of Clinical Pharmacology/Pharmacokinetics/Pharmacokinetics II - Drug Absorption

    Principles of Clinical Pharmacology/Pharmacokinetics/Pharmacokinetics III - Drug Distribution

    Principles of Clinical Pharmacology/Pharmacokinetics/Pharmacokinetics IV - Drug Metabolism and Excretion