Short Synacthen Test

SST flow
  1. Measure an early morning (before 9am) baseline cortisol and ACTH
  2. Give a dose of synthetic ACTH (IV or IM)
  3. Measure serum cortisol 30 minutes later

A normal response is a serum cortisol greater than 500 nmol/L

Anything below this is indicative of adrenal insufficiency.