Skin hyperpigmentation
Skin hyperpigmentation is a classic feature of Addison's but why does it happen?
If you remember the adrenal axis, low cortisol due to an adrenal problem will mean high levels of ACTH.
Melanocyte-Stimulating Hormone (MSH) and ACTH share a common precursor so ACTH can bind to melanocytes and stimulate melanin production.
