a-short-review-of-histology

Ovarian Follicles 1:

Ovarian follicles consist of an oocyte surrounded by follicular cells
At birth there are around 1 million follicles in each ovary
In these follicles the oocyte is arrested at prophase of the first meiotic division
It will remain in prophase of the first meiotic division until the time it is released from a mature follicle (perhaps 40 years or more)
By puberty this number of follicles has been reduced by about half
During the reproductive phase a women may mature about 400-500 follicles and release that number of ova ready to be fertilised
The remaining follicles fail to mature fully and break down: they become atretic

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