Haematology
Aims
Objectives
Primary vs. Secondary Neutrophilia / Thrombocytosis
Primary vs. Secondary Neutrophilia / Thrombocytosis 2
MPD Diagnosis
Somatic Mutations in MPD
Chronic Myeloid Leukaemia (CML)
Myelofibrosis
Case
Differential
History
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Haematology
MPD Diagnosis
Traditionally this was by bone marrow aspirate and trephine
Acquired (somatic) mutations that can be detected in the peripheral blood have now been found
Most patients do not need a bone marrow to diagnose these conditions
