History & Examination
What features in the history & examination help to discriminate primary and secondary thrombocytosis?
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MPD are often discovered incidentally and patients are usually well. Specific symptoms that may be found in MPD are itch, especially after a warm bath or shower ("aquagenic pruritus") and skin redness and burning pain "erythromelalgia". "B symptoms" such as night sweats and weight loss can occur but are not often present in MPD and they suggest other malignant causes should be sought carefully.
