MBChB MRCP DM FRCPath
Chair in Applied Medicine (Clin)
- About
-
- Email Address
- m.a.vickers@abdn.ac.uk
- Telephone Number
- +44 (0)1224 272401
- Office Address
1. Room 3:25, Institute of Medical Sciences
2. Blood Transfusion Centre, Foresterhill Road, Aberdeen AB25 2ZW
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I graduated from Oxford Medical School in 1983, having completed a Biochemistry Part II at Cambridge. After general medical jobs in London, I worked with Doug Higgs on genes surrounding the alpha-globin gene cluster. I then trained in clinical Haematology at the Hammersmith, Reading and John Radcliffe Hospitals (1990–1996). I moved to Aberdeen in 1996 and was promoted to Professor in the section of Applied Medicine in 2008. I took over directorship of the Academic Transfusion Medicine Unit in 2010.
External Memberships
Member of Royal College of Physicians
Fellow of Royal College of Pathologists
British Society for Haematology
- Research
-
Research Overview
My main current interest is in how cells are recognised as being damaged by phagocytes, using red blood cells as the main model system. Our work has implicated unusual glycosylation motifs as being key to the process and are of particular relevance to the mechanism of haemolysis in sickle cell disease and malaria. The mechanism gives insight into splenic function, notably susceptibility to pneumococcal infection. I have interests in cellular immunotherapy, including the use of blood donor derived cytotoxic lymphocytes to treat post-transplant lympoproliferative disease and COVID-19. I am supervising PhD students developing innate immunotherapeutic reagents to treat cancers. I am also involved in collection and use of convalescent plasma for COVID-19.My main current interest is in how cells are recognised as being damaged by phagocytes, using red blood cells as the main model system. Our work has implicated unusual glycosylation motifs as being key to the process and are of particular relevance to the mechanism of haemolysis in sickle cell disease and malaria. The mechanism gives insight into splenic function, notably susceptibility to pneumococcal infection. I have interests in cellular immunotherapy, including the use of blood donor derived cytotoxic lymphocytes to treat post-transplant lympoproliferative disease and COVID-19. I am supervising PhD students developing innate immunotherapeutic reagents to treat cancers. I am also involved in collection and use of convalescent plasma for COVID-19.
Knowledge Exchange
I have given talks about the use of convalescent plasma and T cells to treat COVID-19.
Collaborations
Prof. Alex Rowe, Edinburgh University.
Prof. Stuart Haslam, Imperial College London.
Prof. David Rees, King's College London.
Supervision
Shiva Nickaria, Raquel Ferro, Ellen Main - all working on immunotherapies.
- Teaching
-
Teaching Responsibilities
I organise, and deliver much of, the haematology training in the medical school. I remain an enthusiastic bedside teacher. I co-ordinated the third year medical degree 1997-2010.
- Publications
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Page 1 of 1 Results 1 to 90 of 90
Measurement of erythrocyte membrane mannoses to assess splenic function
British Journal of Haematology, vol. 198, no. 1, pp. 155-164Contributions to Journals: ArticlesHyposplenism and gastrointestinal diseases: significance and mechanisms
Digestive Diseases, vol. 40, pp. 290–298Contributions to Journals: Review articlesOxidative stress, malaria, sickle cell disease, and innate immunity
Trends in Immunology, vol. 42, no. 10, pp. 849-851Contributions to Journals: ArticlesCytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapy
Clinical and Experimental Immunology, vol. 206, no. 1, 68-81Contributions to Journals: ArticlesThe Red Blood Cell as a Novel Regulator of Human B-cell Activation
Immunology, vol. 163, no. 4Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/imm.13327
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16803/1/Lennon_etal_The_red_blood_VOR.pdf
- [ONLINE] View publication in Scopus
Low-Dose Vitamin D3 Supplementation Does Not Affect Natural Regulatory T Cell Population but Attenuates Seasonal Changes in T Cell-Produced IFN-γ: results from the D-SIRe2 randomised controlled trial
Frontiers in Immunology, vol. 12, 623087Contributions to Journals: ArticlesSialic acid‐binding immunoglobulin‐like lectin (Siglec)‐15 is a rapidly internalised cell‐surface antigen expressed by acute myeloid leukaemia cells
British Journal of Haematology, vol. 193, no. 5, pp. 946-950Contributions to Journals: ArticlesRed blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance
Nature Communications, vol. 12, no. 1, 1792Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41467-021-21814-z
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16159/1/Cao_etal_NC_Red_blood_Cell_VoR.pdf
- [ONLINE] View publication in Scopus
Human erythrocyte surface fucose expression increases with age and hyperglycemia: [version 1; peer review: awaiting peer review]
Wellcome open research, vol. 6, 28Contributions to Journals: Articles- [ONLINE] https://doi.org/10.17605/OSF.IO/XF8AM
- [ONLINE] DOI: https://doi.org/10.12688/wellcomeopenres.16409.1
High mannose N-glycans on red blood cells as phagocytic ligands, mediating both sickle cell anaemia and resistance to malaria
bioRxivContributions to Journals: ArticlesParaprotein associated syndrome treated successfully with chemotherapy
BMJ Case Reports, vol. 13, no. 9, e232866Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bcr-2019-232866
- [ONLINE] View publication in Scopus
Long-Term Follow Up After Third Party Viral-Specific Cytotoxic Lymphocytes For Immunosuppression- And Epstein-Barr Virus-Associated Lymphoproliferative Disease
Haematologica, vol. 104, no. 8, pp. e356-e359Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3324/haematol.2018.207548
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Investigating thrombocytosis
BMJ (Online), vol. 366, l4183Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.l4183
- [ONLINE] View publication in Scopus
- [ONLINE] http://www.bmj.com/lookup/doi/10.1136/bmj.l4183
- [ONLINE] View publication in Mendeley
Combination peptide immunotherapy suppresses antibody and helper T cell responses to the major human platelet autoantigen GPIIb/IIIa in HLA-transgenic mice
Haematologica, vol. 104, no. 5, pp. 1074-1082Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3324/haematol.2017.179424
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12261/1/Combination_Peptide_Immunotherapy_Suppresses_Antibody_And_Helper_T_Cell_Responses_To_The_Major_Human_Platelet_Autoantigen_Glycoprotein_IIbIIIa_In_HLA_Transgenic_Mice.pdf
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation
Cells, vol. 8, no. 1, 47Contributions to Journals: Review articlesSimilarities and differences in surface receptor expression by THP-1 monocytes and differentiated macrophages polarized using seven different conditioning regimens
Cellular Immunology, vol. 332, pp. 58-76Contributions to Journals: ArticlesCombined linkage and association analysis of classical Hodgkin lymphoma
Oncotarget, vol. 9, no. 29, pp. 20377-20385Contributions to Journals: ArticlesCytotoxic T-lymphocyte therapy for post-transplant lymphoproliferative disorder after solid organ transplantation in children
Pediatric Transplantation, vol. 22, no. 2, 13133Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/petr.13133
Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia
Cancer Research, vol. 78, no. 1, pp. 75-87Contributions to Journals: ArticlesExteriorisation of Mannoses on Human Erythrocyte Membrane Skeleton Provides 'Eat Me' Signals for Oxidatively Damaged Cells to be Cleared By Macrophages: A Pathway Mediating Hemolysis in Sickle Cell Disease
Blood, vol. 130, no. 1, pp. 919Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood.V130.Suppl_1.919.919
- [ONLINE] View publication in Scopus
Season of infectious mononucleosis as a risk factor for multiple sclerosis: a UK primary care case-control study
Multiple Sclerosis and Related Disorders, vol. 17, pp. 103-106Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.msard.2017.07.009
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10717/2/Revised_Paper_clean.pdf
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10717/1/im_in_ms_flow_chart.tif
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10717/3/Supplemental_Tables.docx
Effective antigen presentation to helper T cells by human eosinophils
Immunology, vol. 149, no. 4, pp. 413-422Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/imm.12658
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9327/1/Farhan_et_al_2016_Immunology.pdf
Leukocyte Ig-Like receptor B1 restrains dendritic cell function through increased expression of the NF-κB regulator ABIN1/TNIP1
Journal of Leukocyte Biology, vol. 100, no. 4, pp. 737-746Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1189/jlb.1A0915-420RRR
Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes
Journal of Allergy and Clinical Immunology, vol. 137, no. 5, pp. 1498-1505Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jaci.2015.12.1311
Intraoperative salvage does not affect expression of markers for erythrophagocytosis
Transfusion Medicine, vol. 26, no. 2, pp. 147-149Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1111/tme.12288
Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and rheumatoid arthritis
Arthritis Research & Therapy, vol. 17, pp. 274Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s13075-015-0755-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4995/1/s13075_015_0755_6.pdf
Intraoperative cell salvage may damage erythrocytes as indicated by macrophage uptake
Annual Meeting of the Society-of-Academic-and-Research-Surgery (SARS(, pp. 31-31Contributions to Journals: AbstractsHow do immune responses differ against senescent and damaged erythrocytes: profiling sugar and protein changes on the cell surface
Immunology, vol. 143, no. s2, pp. 118-119Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1111/imm.12406
Establishment and operation of a Good Manufacturing Practice-compliant allogeneic Epstein-Barr virus (EBV)-specific cytotoxic cell bank for the treatment of EBV-associated lymphoproliferative disease
British Journal of Haematology, vol. 167, no. 3, pp. 402-410Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/bjh.13051
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4107/1/bjh13051.pdf
Human interleukin-27: wide individual variation in plasma levels and complex inter-relationships with interleukin-17A
Clinical and Experimental Immunology, vol. 178, no. 2, pp. 373-383Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/cei.12408
Combination peptide immunotherapy suppresses antibody and helper T cell responses to the RhD protein in HLA-transgenic mice
54th Annual Scientific Meeting of the British-Society-for-Haematology, pp. 12-12Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1111/bjh.12802
Expansion of Foxp3+ T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge
European Journal of Immunology, vol. 44, no. 4, pp. 1069-1083Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/eji.201343604
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3241/1/EJI_whibley.pdf
The epidemiology of infectious mononucleosis in Northern Scotland: a decreasing incidence and winter peak
BMC Infectious Diseases, vol. 14, 151Contributions to Journals: ArticlesCombination peptide immunotherapy suppresses antibody and helper T cell responses to the RhD protein in HLA-transgenic mice
Haematologica, vol. 99, no. 3, pp. 588-596Contributions to Journals: ArticlesSystematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and systemic lupus erythematosus
Arthritis Research & Therapy, vol. 16, no. 1, R3Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/ar4429
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5476/1/ar4429.pdf
Quantitative variation in plasma angiotensin-i converting enzyme activity shows allelic heterogeneity in the ABO blood group locus
Annals of Human Genetics, vol. 77, no. 6, pp. 465-471Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/ahg.12034
- [ONLINE] View publication in Scopus
The soluble isoform of CTLA-4 as a regulator of T-cell responses
European Journal of Immunology, vol. 43, no. 5, pp. 1274-1285Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/eji.201242529
Systematic review and meta-analysis of the sero-epidemiological association between Epstein Barr virus and multiple sclerosis
PloS ONE, vol. 8, no. 4, e61110Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0061110
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3605/1/Systematic_review.pdf
Acute myeloid leukemia presenting in a mother and daughter pair with the identical acquired karyotypic abnormality consisting of inversion 3q21q26 and monosomy 7: a review of possible mechanisms
Cancer Genetics and Cytogenetics, vol. 205, no. 11, pp. 599-602Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.cancergen.2012.09.001
Production of the effector cytokine interleukin-17, rather than interferon-γ, is more strongly associated with autoimmune hemolytic anemia
Haematologica, vol. 97, no. 10, pp. 1494-1500Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3324/haematol.2011.060822
Candida albicans evades protective immunity by promoting the expansion of induced CD4(+) CD25(+) FoxP3(+) Helioslo regulatory T cells that enhance Th17 responses
European Congress of Immunology, pp. 206-206Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1111/imm.12002
Identification, immunomodulatory activity, and immunogenicity of the major helper T-cell epitope on the K blood group antigen
Blood, vol. 119, no. 23, pp. 5563-5574Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2012-02-410324
Effects of ultraviolet light on human serum 25-hydroxyvitamin D and systemic immune function
Journal of Allergy and Clinical Immunology, vol. 129, no. 6, pp. 1554-1561Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jaci.2012.03.001
Candida albicans promotes the differentiation of induced CD4(+) CD25(+) Foxp3(+) regulatory T cells
Immunology, vol. 135, no. Suppl. 1, pp. 161Contributions to Journals: AbstractsEvidence-based focused review of the treatment of idiopathic warm immune hemolytic anemia in adults
Blood, vol. 118, no. 15, pp. 4036-4040Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2011-05-347708
Foundation Years Journal
Other Contributions: Other ContributionsThe doctor's dilemma: stimulating T cells
Blood, vol. 114, no. 16, pp. 3361-3362Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1182/blood-2009-08-236778
Helper T cells point the way to specific immunotherapy for autoimmune disease
Cardiovascular & Hematological Disorders - Drug Targets, vol. 9, no. 3, pp. 159-166Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2174/187152909789007043
A case of apples and pears?
Blood, vol. 113, no. 24, pp. 6259-6260Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1182/blood-2009-03-211169
Genetic variants linked to coronary artery disease are not associated with carotid artery intima-media thickness or intermediate risk phenotypes
Atherosclerosis, vol. 203, no. 1, pp. 41-44Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.atherosclerosis.2008.06.025
Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma
Blood, vol. 111, no. 11, pp. 5359-5370Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2007-08-105395
Clonal regulatory T cells specific for a red blood cell autoantigen in human autoimmune hemolytic anemia
Blood, vol. 111, no. 2, pp. 680-687Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2007-07-101345
A high rate of CLL phenotype lymphocytes in autoimmune haemolytic anaemia and immune thrombocytopenic purpura
Haematologica, vol. 93, no. 1, pp. 151-152Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3324/haematol.11822
ABO(H) blood groups and vascular disease: a systematic review and meta-analysis
Journal of Thrombosis and Haemostasis, vol. 6, no. 1, pp. 62-69Contributions to Journals: Literature Reviews- [ONLINE] DOI: https://doi.org/10.1111/j.1538-7836.2007.02818.x
CD4(+) T-cell responses to Epstein-Barr virus (EBV) latent membrane protein 1 in infectious mononucleosis and EBV-associated non-Hodgkin lymphoma: Th1 in active disease but Tr1 in remission
British Journal of Haematology, vol. 139, no. 1, pp. 81-89Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1365-2141.2007.06765.x
JAK2 V617F-positive polycythemia rubra vera maintained by approximately 18 stochastic stem cell divisions/year, explaining age of onest by a single rate-limiting mutation
Blood, vol. 110, no. 5, pp. 1675-1680Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/BLOOD-2006-12-061911
The relationships between Epstein-Barr virus latent membrane protein 1 and regulatory T cells in Hodgkin's lymphoma
Experimental Hematology, vol. 35, no. 4, pp. 596-604Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/J.EXPHEM.2007.01.030
Controlling autoimmunity—Lessons from the study of red blood cells as model antigens
Immunology Letters, vol. 108, no. 1, pp. 20-26Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.imlet.2006.10.005
X inactivation patterns of closely, but not distantly, related cells are highly correlated: little evidence for stem cell plasticity in normal females
Stem Cells, vol. 24, no. 11, pp. 2398-2405Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1634/stemcells.2006-0043
Rh autoantigen presentation to helper T cells in chronic lymphocytic leukemia by malignant B cells
Blood, vol. 105, no. 5, pp. 2007-2015Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2003-10-3563
Pro-coagulant effects of environmental particles (PM10)
Occupational and Environmental Medicine, vol. 62, pp. 164-171Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/oem.2004.014951
Pyoderma gangrenosum as a cause of splenomegaly and association with a T-cell clone.
Clinical and Laboratory Haematology, vol. 27, pp. 402-404Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1365-2257.2005.00730.x
The cryptic path from epitope to clot: a story of two domains?
Blood, vol. 105, pp. 1371-1372Contributions to Journals: Editorials- [ONLINE] DOI: https://doi.org/10.1182/blood-2004-11-4556
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma
Blood, vol. 103, no. 5, pp. 1755-1762Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2003-07-2594
Pulmonary and systemic effects of short-term inhalation exposure to ultrafine carbon black particles.
Toxicology and Applied Pharmacology, vol. 195, pp. 35-44Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.taap.2003.10.003
Markers of endothelial activation and atherothrombosis in women with history of preeclampsia or gestational hypertension
Thrombosis and Haemostasis, vol. 90, no. 6, pp. 1192-1197Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1
Journal of Immunology, vol. 170, no. 12, pp. 6183-6189Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.4049/jimmunol.170.12.6183
- [ONLINE] View publication in Scopus
Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 11
The Journal of Immunology, vol. 170, no. 12, pp. 6183-6189Contributions to Journals: ArticlesFatal myelodysplastic syndrome developing during therapy with imatinib mesylate and characterised by the emergence of complex Philadelphia negative clones [1]
Leukemia, vol. 17, no. 3, pp. 634-635Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1038/sj.leu.2402842
- [ONLINE] View publication in Scopus
Imatinib mesylate-induced molecular remission of Philadelphia chromosome-positive myelodysplastic syndrome [3]
Leukemia, vol. 17, no. 2, pp. 463-465Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1038/sj.leu.2402814
- [ONLINE] View publication in Scopus
Cellular turnover of normal gastrointestinal epithelium assessed by changes in telomeric: total DNA signal ratios
European Journal of Gastroenterology & Hepatology, vol. 15, no. 11, pp. 1195-1201Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/00042737-200311000-00008
Markers of endothelial activation and atherothrombosis in women with history of pre-eclampsia or gestational hypertension
Thrombosis and Haemostasis, vol. 90, no. 6, pp. 1192-1197Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1160/TH03-01-0053
Polymorphisms in the interleukin-10 and interferon gamma genes in Hodgkin lymphoma
Leukemia & Lymphoma, vol. 44, no. 12, pp. 2083-2088Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/1042819031000119316
Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen
Blood, vol. 100, no. 13, pp. 4529-4536Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2002-05-1383
Prothrombotic genotypes are not associated with pre-eclampsia and gestational hypertension: results from a large population-based study and systematic review
Thrombosis and Haemostasis, vol. 87, no. 5, pp. 779-785Contributions to Journals: ArticlesEstimation of mutation rate at human glycophorin A locus in hematopoietic stem cell progenitors
Environmental and Molecular Mutagenesis, vol. 39, no. 4, pp. 333-341Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/em.10076
Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein
Cardiovascular Research, vol. 53, no. 4, pp. 1029-1034Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0008-6363(01)00534-X
The ninety-fifth annual general meeting of the association of physicians of Great Britain and Ireland 2001
QJM - Monthly Journal of the Association of Physicians, vol. 94, no. 11, pp. 643-655Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Assessment of mechanism of acquired skewed X inactivation by analysis of twins
Blood, vol. 97, no. 5, pp. 1274-1281Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood.V97.5.1274
Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke
Stroke, vol. 32, no. 1, pp. 57-62Contributions to Journals: ArticlesEvidence for a quantitative trait locus for plasma fibrinogen from a family-based association study.
Genescreen, vol. 1, pp. 151-155Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1046/j.1466-920x.2001.00037.x
In vivo platelet activation in atherothrombotic stroke is not determined by polymorphisms of human platelet glycoprotein IIIa or Ib
British Journal of Haematology, vol. 112, no. 3, pp. 621-631Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1046/j.1365-2141.2001.02620.x
Monosomy for the most telomeric, gene-rich region of human chromosome 16p causes minimal phenotypic effects
EJHG : European journal of human genetics : the official journal of the European Society of Human Genetics. , vol. 9, pp. 217-225Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/sj.ejhg.5200610
Beta-tubulin gene mutations and response to vinca alkaloids in acute lymphoblastic leukaemia
Journal of Medical Genetics, vol. 37, no. Supplement, pp. S42Contributions to Journals: ArticlesGenetic basis of variation in fibrinogen and CRP
Heart, vol. 83, no. SUPPL. 1Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Modelling haemopoietic stem cell division by analysis of mutant red cells
British Journal of Haematology, vol. 110, pp. 54-62Contributions to Journals: ArticlesThe incidence of acute promyelocytic leukemia appears constant over most of a human lifespan, implying only one rate limiting mutation
Leukemia, vol. 14, pp. 722-726Contributions to Journals: ArticlesSplenic irradiation before bone marrow transplantation for chronic myeloid leukaemia (multiple letters) [9]
British Journal of Haematology, vol. 97, no. 1, pp. 248-249Contributions to Journals: Letters- [ONLINE] View publication in Scopus
More or less hematopoietic stem cells
Nature Medicine, vol. 2, no. 12, pp. 1281-1282Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1038/nm1296-1281b
- [ONLINE] View publication in Scopus
Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data
Contributions to Journals: Short Survey- [ONLINE] DOI: https://doi.org/10.1046/j.1365-2141.1996.d01-1751.x
- [ONLINE] View publication in Scopus