Advanced Research Fellow
- About
-
- Email Address
- c.s.whyte@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437897
- Office Address
Lab 1.33 Office 3.47:6
Institute of Medical Sciences
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am an Advanced Research Fellow at the Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Science. I obtained my PhD in Medical Sciences at Rowett Research Institute of Nutrition and Health through the University of Aberdeen. My research to date has focused on cellular regulation of fibrinolysis with a particular interest in the role of platelets in directing this process. I have also investigated fibrinolytic dysregulation in disease situations including COVID-19, DVT and stroke. I have recently started on a Transition to Independence Fellowship funded by Friends of Anchor to investigate dysregulated fibrinolysis in cancer associated thrombosis.
Qualifications
- PhD Medical Sciences2009 - University of Aberdeen
Memberships and Affiliations
- Internal Memberships
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Nvision Researcher Development Network Committee
Postdoctoral Research Committee - Institute of Medical Sciences Representative
Institute of Medical Sciences Health and Safety Committee - ECR Representative
- External Memberships
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British Society for Haemostasis and Thrombosis Committee
Council Member (Class of 2027) - International Society for Fibrinolysis and Proteolysis
Latest Publications
Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation
Blood Advances, 2024012979Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/bloodadvances.2024012979
Fibrinogenolysis and fibrinolysis in Vaccine-induced Immune Thrombocytopenia and Thrombosis (VITT)
Journal of Thrombosis and Haemostasis, vol. 21, no. 12, pp. 3589-3596Contributions to Journals: ArticlesNovel therapeutics and emerging technology in haemostasis and thrombosis: highlights from the British society for haemostasis and thrombosis annual meeting
Frontiers in cardiovascular medicine, vol. 10, 1225243.Contributions to Journals: ArticlesPlatelet factor XIII-A regulates platelet function and promotes clot retraction and stability
Research and Practice in Thrombosis and Haemostasis, vol. 7, no. 5, 100200Contributions to Journals: ArticlesAll tangled up: interactions of the fibrinolytic and innate immune systems
Frontiers in Medicine, vol. 10, 1212201Contributions to Journals: Articles
Prizes and Awards
D. Collen Young Investigator Award runner up 2023
D. Collen Young Investigator Award runner up 2018
- Research
-
Supervision
Supervisees
- MR ANUJ NARWAL
- MR KIERAN POCKNELL
- MR STEVEN HUMPHREYS
- Publications
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Page 3 of 3 Results 21 to 26 of 26
Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow
Blood, vol. 125, no. 16, pp. 2568 - 2578Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2014-09-599480
Functional factor XIII-A is exposed on the stimulated platelet surface
Blood, vol. 124, no. 26, pp. 3982–3990Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1182/blood-2014-06-583070
A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in vitro and in vivo
Immunology, vol. 141, no. 1, pp. 96-110Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/imm.12173
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5484/1/Arnold_et_al_2014_Immunology.pdf
N-3 long-chain polyunsaturated fatty acids inhibit smooth muscle cell migration by modulating urokinase plasminogen activator receptor through MEK/ERK-dependent and -independent mechanisms
The Journal of Nutritional Biochemistry, vol. 23, no. 11, pp. 1378-1383Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jnutbio.2011.08.005
Impact of fibrin structure on fibrinolysis by different plasminogen activators: studies using fluorescent confocal microscopy
Journal of Thrombosis and Haemostasis, vol. 10, no. 6, pp. E24Contributions to Journals: Reviews of Books, Films and Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1538-7836.2012.04749.x
Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function
Journal of Leukocyte Biology, vol. 90, no. 5, pp. 845-854Contributions to Journals: Articles- [ONLINE] http://www.ncbi.nlm.nih.gov/pubmed/21628332
- [ONLINE] DOI: https://doi.org/10.1189/jlb.1110644