Dr Seonaidh Cotton

Dr Seonaidh Cotton
Dr Seonaidh Cotton
Dr Seonaidh Cotton

BSc (Hons), MLitt, PhD

Senior Trial Manager

About
Email Address
s.c.cotton@abdn.ac.uk
Telephone Number
+44 (0)1224 438178
Office Address

Health Services Research Unit Health Sciences Building (Third Floor) Foresterhill Aberdeen AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I joined HSRU in 2007 as a trial manager.  I graduated from the University of Aberdeen with a BSc in Health Sciences in 1993, an MLitt in 1995, and a PhD in 2007.  Prior to joining the Unit, I worked in the Department of Public Health at the University of Aberdeen.

I am the Senior Trial Manager within CHaRT supporting the portfolio of trials.   I also currently work on the BICS trial - a multicentre trial investigating the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.    

Previously I was the Deputy Senior Trial Manager and supported a number of studies including RAACENOEMPOWER and ELECTRIC (all now completed).  I also worked as trial manager on a number of CHaRT trials, including TWICSCLASSNIAMIFOCCUSREFLUX and the Cysteamine in CF study.  

I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.

 

Qualifications

  • BSc Health Sciences 
    1993 - University of Aberdeen 
  • MLitt by research 
    1994 - University of Aberdeen 
  • PhD Public Health 
    2008 - University of Aberdeen 
Research

Research Overview

Trial methodology & trial management

Research Areas

Applied Health Sciences

Nutrition and Health

Current Research

I am the Senior Trial Manager within CHaRT supporting the portfolio of trials.   I also currently work on the BICS trial - a multicentre trial investigating the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.    

I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.

Past Research

Since joining the Unit I have worked on a number of trials that have now been completed. 

TWICS  - a multicentre trial investigating the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease.

CLASS - a multicentre trial comparing foam sclerotherapy and endovenous laser ablation with conventional surgery in patients with varicose veins;

NIAMI - a phase II multicentre trial investigating whether an intravenous injection of sodium nitrite given immediately before the infarct related artery is opened reduces ischaemia reperfusion injury in patients with myocardial infarction;

FOCCUS - a pragmatic multi-centred randomised controlled trial of surgical HDU care versus HDU care delivered in an ICU and pre-operative fluid loading in high-risk patients undergoing major elective surgery

REFLUX - a multi-centre randomised trial comparing a policy of relatively early laparoscopic surgery with a continued best medical management policy for people with more severe gastro-oesophageal reflux disease.

The Cysteamine in CF study - a single-centre, single group open label study of oral cysteamine in patients with Cystic Fibrosis.

I also supported RAACENOEMPOWER and ELECTRIC (all now completed) as senior trial manager.

Teaching

Teaching Responsibilities

I have supervised a number of undergraduate and Masters level research projects, including topics such as provision of information to potential participants, strategies to increase response rates, and outcome measures.

 

 

Non-course Teaching Responsibilities

Outwith the University, I am a faculty member on the Edinburgh Clinical Trial Management Course (ECTMC).

 

Publications

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  • HPV immunisation and cervical screening - confirmation of changed performance of cytology as a screening test in immunised women: a retrospective population based cohort study

    Palmer, T. J., McFadden, M., Pollock, K. G. J., Kavanagh, K., Cuschieri, K., Cruickshank, M., Cotton, S., Nicoll, S., Robertson, C.
    British Journal of Cancer, vol. 114, no. 5, pp. 582-589
    Contributions to Journals: Articles
  • Behavioural recovery after treatment for varicose veins

    Cotton, S. C., MacLennan, G., Brittenden, J., Prior, M., Francis, J.
    British Journal of Surgery, vol. 103, no. 4, pp. 374-381
    Contributions to Journals: Articles
  • Impact of post-colposcopy management on women's long-term worries: results from the UK population-based TOMBOLA trial

    Sharp, L., Cotton, S., Cruickshank, M., Gray, N., Smart, L., Whynes, D., Little, J., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Journal of Family Planning and Reproductive Health Care, vol. 42, no. 1, pp. 43-51
    Contributions to Journals: Articles
  • Decision aids for people considering taking part in clinical trials

    Gillies, K., Cotton, S. C., Brehaut, J. C., Politi, M. C., Skea, Z.
    Cochrane Database of Systematic Reviews, no. 11, CD009736
    Contributions to Journals: Articles
  • Long-term Worries after Colposcopy: Which Women Are at Increased Risk?

    Sharp, L., Cotton, S. C., Cruickshank, M. E., Gray, N. M., Neal, K., Rothnie, K., Thornton, A. J., Walker, L. G., Little, J., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Women's Health Issues, vol. 25, no. 5, pp. 517-527
    Contributions to Journals: Articles
  • SMS text pre-notification and delivery of reminder e-mails to increase response rates to postal questionnaires in the SUSPEND trial: a factorial design, randomised controlled trial

    Starr, K., McPherson, G., Forrest, M., Cotton, S. C.
    Trials, vol. 16, 295
    Contributions to Journals: Articles
  • Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial

    Devereux, G., Cotton, S., Barnes, P., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J. A. F., Lee, A. J., McCormack, K., McPherson, G., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Price, D.
    Trials, vol. 16, 267
    Contributions to Journals: Articles
  • Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform

    Treweek, S., Altman, D. G., Bower, P., Campbell, M., Chalmers, I., Cotton, S., Craig, P., Crosby, D., Davidson, P., Devane, D., Duley, L., Dunn, J., Elbourne, D., Farrell, B., Gamble, C., Gillies, K., Hood, K., Lang, T., Littleford, R., Loudon, K., McDonald, A., McPherson, G., Nelson, A., Norrie, J., Ramsay, C., Sandercock, P., Shanahan, D. R., Summerskill, W., Sydes, M., Williamson, P., Clarke, M.
    Trials, vol. 16, 261
    Contributions to Journals: Articles
  • A normal colposcopy examination fails to provide psychological reassurance for women who have had low-grade abnormal cervical cytology

    Cotton, S. C., Sharp, L., Little, J., Gray, N. M., Walker, L. G., Whynes, D. K., Cruickshank, M. E., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Cytopathology, vol. 26, no. 3, pp. 178-187
    Contributions to Journals: Articles
  • Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial

    Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M., Bolsover, D., Campbell, M. K.
    Health Technology Assessment, vol. 19, no. 27, pp. 1-342
    Contributions to Journals: Articles
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