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Health Economics Research Unit (HERU)

Professor Graeme MacLennan

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Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • The mellow babies trial: a randomised controlled trial to assess the clinical and cost-effectiveness of the Mellow Babies programme for mothers experiencing psychosocial stress

    Thompson, L., Tanner, J., Breckons, M., Young, N., Ternent, L., Vadiveloo, T., Wilson, P., Wight, D., Marryat, L., McGowan, I., MacLennan, G., MacBeth, A., McTaggart, J., Allison, T., Norrie, J.
    Public Health Research
    Contributions to Journals: Articles

  • Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units

    Kaye, C., Rhodes, J., Austin, P., Casey, M., Gould, R., Sira, J., Treweek, S., MacLennan, G.
    BJA Open, vol. 10, 100287
    Contributions to Journals: Articles

  • Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

    Innes, K., Ahmed, I., Hudson, J., Hernández, R. A., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    Health Technology Assessment, vol. 28, no. 26, pp. 1-151
    Contributions to Journals: Articles

  • Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial

    Devereux, G., Cotton, S., Nath, M., McMeekin, N., Campbell, K., Chaudhuri, R., Choudhury, G., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J., Lee, A. J., MacLennan, G., Morice, A., Norrie, J., Price, D., Short, P., Vestbo, J., Walker, P., Wedzicha, J., Wilson, A., Wu, O., Lipworth, B. J.
    JAMA, vol. 332, no. 6, pp. 462-470
    Contributions to Journals: Articles

  • Complexity of Trials on Pain Management in Acute Pancreatitis: An Ongoing Challenge

    Kamarajah, S. K., Maclennan, G., Pandanaboyana, S.
    Clinical Gastroenterology and Hepatology
    Contributions to Journals: Letters

  • Prevalencia del cáncer del tracto urinario. Análisis de la cohorte española del estudio IDENTIFY

    Toribio-Vázquez, C., Gómez Rivas, J., Amigo, F., Carrión, D. M., Yebes, , Alonso-Bartolomé, M., Ayllon, H., Aguilera, A., Martinez-Pineiro, L., Antón-Juanilla, M., Crespo-Atín, V., Otaola-Arca, H., Herranz-Yague, J. A., Munoz Rivero, M. V., MacKenzie, K. R., Shah, T. T., Gao, C., Zimmermann, E., Jefferies, M., Nambiar, A., Gallagher, K. M., Khadhouri, S., Kasivisvanathan, V., Moore, S., Zimmermann, E. F., Edison, E., Mannas, M. P., Lee, T., Marra, G., Lillaz, B., Olivier, J., Assmus, M. A., Uçar, T., Claps, F., Boltri, M., Burnhope, T., Nkwam, N., Tanasescu, G., Boxall, N. E., Downey, A. P., Ahmed Lal, A., Clarke, H., HW Lau, D., Gillams, K., Crockett, M., Nielsen, M., Takwoingi, Y., Chuchu, N., O'Rourke, J., MacLennan, G., IDENTIFY Study group
    Actas Urologicas Espanolas, vol. 48, no. 3, pp. 228-237
    Contributions to Journals: Articles

  • Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients With Exsanguinating Hemorrhage-Reply

    Jansen, J. O., MacLennan, G. S., Campbell, M. K.
    JAMA, vol. 331, no. 11, pp. 981-982
    Contributions to Journals: Comments and Debates

  • Reply to Arnulf Stenzl, Morgan Rouprêt, J. Alfred Witjes, Paolo Gontero. High-quality Transurethral Resection of Bladder Tumour Needs Additional Forms of Tumour Delineation. Eur Urol 2023;83:193–4

    Heer, R., Tan, W. S., Gravestock, P., Vadiveloo, T., Lewis, R., Penegar, S., Vale, L., MacLennan, G., Hall, E., PHOTO Trial Team
    European Urology, vol. 85, no. 3, pp. 309-312
    Contributions to Journals: Comments and Debates

  • SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial

    Long, M. B., Abo-Leyah, H., Giam, Y. H., Vadiveloo, T., Hull, R. C., Keir, H. R., Pembridge, T., De Lima, D. A., Delgado, L., Inglis, S. K., Hughes, C., Gilmour, A., Gierlinski, M., New, B. J., Maclennan, G., Dinkova-Kostova, A. T., Chalmers, J. D.
    ERJ Open Research, vol. 10, no. 2, 00917-2023
    Contributions to Journals: Articles

  • Three-year cost utility analysis of mini versus standard slings: A trial based economic evaluation

    Kilonzo, M., Boyers, D., Cooper, D., Davidson, T., Bhal, K., N'Dow, J., MacLennan, G., Norrie, J., Abdel-Fattah, M.
    BJUI Compass, vol. 5, no. 2, pp. 230-239
    Contributions to Journals: Articles
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