Professor Graeme MacLennan

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Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Systematic Review of Adrenalectomy and Lymph Node Dissection in Locally Advanced Renal Cell Carcinoma

    Bekema, H. J., Maclennan, S., Imamura, M., Lam, T. B. L., Stewart, F., Scott, N., Maclennan, G., McClinton, S., Griffiths, T. R. L., Skolarikos, A., Maclennan, S. J., Sylvester, R., Ljungberg, B., N'dow, J.
    European Urology, vol. 64, no. 5, pp. 799-810
    Contributions to Journals: Articles
  • Calcium supplements and cancer risk: a meta-analysis of randomised controlled trials

    Bristow, S. M., Bolland, M. J., Maclennan, G. S., Avenell, A., Grey, A., Gamble, G. D., Reid, I. R.
    British Journal of Nutrition, vol. 110, no. 8, pp. 1384-1393
    Contributions to Journals: Articles
  • Effect of day and time of admission on mortality in an intensive care unit

    Jansen, J. O., Maclennan, G. S., Cuthbertson, B. H.
    Journal of the Intensive Care Society, vol. 14, no. 4, pp. 294-298
    Contributions to Journals: Articles
  • Management of the open abdomen: A national study of clinical outcome and safety of negative pressure wound therapy

    Carlson, G. L., Patrick, H., Amin, A. I., McPherson, G., Maclennan, G., Afolabi, E., Mowatt, G., Campbell, B.
    Annals of Surgery, vol. 257, no. 6, pp. 1154-1159
    Contributions to Journals: Articles
  • Authors' reply - Assessing catheter-associated urinary tract infection

    Pickard, R., MacLennan, G., Norrie, J., N'Dow, J.
    The Lancet, vol. 381, no. 9877, pp. 1536
    Contributions to Journals: Letters
  • Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)

    Siddiqi, N., Bruce, M., Neil, C. J., Jagpal, B., MacLennan, G. S., Cotton, S. C., Papadopoulo, S. A., Bunce, N., Lim, P., Schwarz, K., Singh, S., Hildick-Smith, D., Horowitz, J. D., Madhani, M., Boon, N., Kaski, J., Dawson, D., Frenneaux, M. P.
    Journal of translational medicine, vol. 11, 116
    Contributions to Journals: Articles
  • Mortality and quality of life in the five years after severe sepsis

    Cuthbertson, B. H., Elders, A., Hall, S., Taylor, J., Maclennan, G., Mackirdy, F., Mackenzie, S. J., Scottish Critical Care Trials Group and the Scottish Intensive Care Society Audit Group
    Critical Care, vol. 17, no. 2, R70
    Contributions to Journals: Articles
  • Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement

    Breeman, S., Campbell, M. K., Dakin, H., Fiddian, N., Fitzpatrick, R., Grant, A., Gray, A., Johnston, L., MacLennan, G. S., Morris, R. W., Murray, D. W., KAT Trial Group
    Journal of Bone & Joint Surgery (US Volume), vol. 95-B, no. 4, pp. 486-492
    Contributions to Journals: Articles
  • Antimicrobial catheters for reduction of symptomatic urinary tract infection in adults requiring short-term catheterisation in hospital: a multicentre randomised controlled trial

    Pickard, R., Lam, T., Maclennan, G., Starr, K., Kilonzo, M., McPherson, G., Gillies, K., McDonald, A., Walton, K., Buckley, B., Glazener, C., Boachie, C., Burr, J., Norrie, J., Vale, L., Grant, A., N'Dow, J.
    The Lancet, vol. 380, no. 9857, pp. 1927-1935
    Contributions to Journals: Articles
  • Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer

    MacLennan, S., Imamura, M., Lapitan, M. C., Omar, M. I., Lam, T. B. L., Hilvano-Cabungcal, A. M., Royle, P., Stewart, F., MacLennan, G., MacLennan, S. J., Dahm, P., Canfield, S. E., McClinton, S., Griffiths, T. R. L., Ljungberg, B., N'Dow, J., UCAN Systematic Review Reference Group
    European Urology, vol. 62, no. 6, pp. 1097-1117
    Contributions to Journals: Articles
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