Director (CHaRT)
- About
-
- Email Address
- g.maclennan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438147
- Office Address
Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
Qualifications
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
- Research
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Research Overview
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
- Teaching
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Teaching Responsibilities
I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.
- Publications
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Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units
BJA Open, vol. 10, 100287Contributions to Journals: ArticlesLaparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT
Health Technology Assessment, vol. 28, no. 26, pp. 1-151Contributions to Journals: ArticlesBisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial
JAMA, vol. 332, no. 6, pp. 462-470Contributions to Journals: ArticlesPrevalencia del cáncer del tracto urinario. Análisis de la cohorte española del estudio IDENTIFY
Actas Urologicas Espanolas, vol. 48, no. 3, pp. 228-237Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.acuro.2023.06.004
- [ONLINE] View publication in Scopus
Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients With Exsanguinating Hemorrhage-Reply
JAMA, vol. 331, no. 11, pp. 981-982Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1001/jama.2024.0285
PUrE RCT 1: Clinical and cost-effectiveness of flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones ≤10 mm
European Urology, vol. 85, no. Supplement 1, pp. S529Contributions to Journals: AbstractsPUrE RCT 2: Clinical and cost-effectiveness of FURS and percutaneous nephrolithotomy for lower pole stones 10-25mm
European Urology, vol. 85, no. Supplement 1, pp. S537Contributions to Journals: AbstractsReply to Arnulf Stenzl, Morgan Rouprêt, J. Alfred Witjes, Paolo Gontero. High-quality Transurethral Resection of Bladder Tumour Needs Additional Forms of Tumour Delineation. Eur Urol 2023;83:193–4
European Urology, vol. 85, no. 3, pp. 309-312Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1016/j.eururo.2023.05.040
- [ONLINE] View publication in Scopus
SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial
ERJ Open Research, vol. 10, no. 2, 00917-2023Contributions to Journals: ArticlesThree-year cost utility analysis of mini versus standard slings: A trial based economic evaluation
BJUI Compass, vol. 5, no. 2, pp. 230-239Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/bco2.303
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22315/2/Kilonzo_etal_BJUIC_Three_Year_Cost_VoR.pdf
- [ONLINE] View publication in Scopus
Effects of socioeconomic status on baseline values and outcomes at 24 months in the Treatment of Advanced Glaucoma Study randomised controlled Trial
British Journal of Ophthalmology, vol. 108, no. 2, pp. 203-210Contributions to Journals: ArticlesHow surgical Trainee Research Collaboratives achieve success: a mixed methods study to develop trainee engagement strategies
BMJ Open, vol. 13, no. 12, e072851Contributions to Journals: ArticlesEffectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial
BMJ, vol. 383, e075383Contributions to Journals: ArticlesCost-effectiveness of cognitive behavioural and personalised exercise interventions for reducing fatigue in inflammatory rheumatic diseases
Rheumatology, vol. 62, no. 12, pp. 3819-3827Contributions to Journals: ArticlesDevelopment of an intervention to manage benzodiazepine dependence and high-risk use in the context of escalating drug related deaths in Scotland: an application of the MRC framework
BMC Health Services Research, vol. 23, no. 1, 1205Contributions to Journals: ArticlesEmergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients with Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial
JAMA, vol. 330, no. 19, pp. 1862-1871Contributions to Journals: ArticlesCost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma
British Journal of Ophthalmology, vol. 107, no. 10, pp. 1452-1457Contributions to Journals: ArticlesPatient preferences for stress urinary incontinence treatments: a discrete choice experiment
BMJ Open, vol. 13, no. 8, pp. e066157Contributions to Journals: ArticlesPROSPECT: 4- and 6-year follow-up of a randomised trial of surgery for vaginal prolapse
International Urogynecology Journal, vol. 34, pp. 67-78Contributions to Journals: ArticlesCost utility analysis of shockwave lithotripsy versus ureteroscopic stone treatment in adults
BJU International, vol. 131, no. 2, pp. 253-261Contributions to Journals: ArticlesCorrection to: Pulpotomy for the Management of Irreversible Pulpitis in Mature Teeth (PIP): a feasibility study (Pilot and Feasibility Studies, (2022), 8, 1, (77), 10.1186/s40814-022-01029-9)
Pilot and Feasibility Studies, vol. 8, 82Contributions to Journals: Comments and DebatesSingle-incision mini-slings versus standard synthetic mid-urethral slings for surgical treatment of stress urinary incontinence in women: The SIMS RCT
Health technology assessment (Winchester, England), vol. 26, no. 47, pp. 1-190Contributions to Journals: ArticlesRandomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study
Trials, vol. 23, no. 1, 630Contributions to Journals: ArticlesDeveloping a Diagnostic Multivariable Prediction Model for Urinary Tract Cancer in Patients Referred with Haematuria: results from the IDENTIFY Collaborative Study
European Urology Focus, vol. 8, no. 6, pp. 1673-1682Contributions to Journals: ArticlesPhotodynamic versus white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer: PHOTO RCT
Health technology assessment (Winchester, England), vol. 26, no. 40, pp. 1-144Contributions to Journals: Articles
