Search
Health Economics Research Unit (HERU)

Professor Graeme MacLennan

In this section
Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

Page 1 of 11 Results 1 to 25 of 265

  • Secondary analysis of the Game of Stones trial for men with obesity: Examining moderator effects and exploratory outcomes

    Dombrowski, S. U., Hoddinott, P., Macaulay, L., O’Dolan, C., Swingler, J., Cotton, S., Avenell, A., Getaneh, A., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M. C., Torrens, C., Turner, K., Van der Pol, M., MacLennan, G.
    Obesity
    Contributions to Journals: Articles

  • Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK: a multicentre, superiority, parallel, open-label, randomised controlled trial

    Abdel-Fattah, M., Chapple, C., Cooper, D., Breeman, S., Bell-Gorrod, H., Kuppanda, P., Guerrero, K. L., Dixon, S., Cotterill, N., Ward, K., Hashim, H., Monga, A., Brown, K., Drake, M. J., Gammie, A., Mostafa, A., Bruce, R., Bell, V., Kennedy, C., Evans, S., MacLennan, G., Norrie, J., FUTURE Study Group
    The Lancet
    Contributions to Journals: Articles

  • CATHETER II, a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Cotton, S., Norrie, J., MacLennan, G., Catheter II Team
    European Association of Urology Annual Congress 2025, pp. A0090
    Contributions to Conferences: Abstracts

  • Patients and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial

    Tripathee, S., Abdel-Fattah, M., Johnson, D., Constable, L., Cotton, S., Cooper, D., MacLennan, G., Evans, S., Young, A. J., Dimitropoulos, K., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., Murchie, P., Myint, P. K., N'Dow, J., Paterson, C., Powell, K., Scotland, G., Thiruchelvam, N., Norrie, J., Omar, M. I., MacLennan, S.
    BMJ Open
    Contributions to Journals: Articles

  • Updated Systematic Review and Meta-analysis of Extracorporeal Shock Wave Lithotripsy, Flexible Ureterorenoscopy, and Percutaneous Nephrolithotomy for Lower Pole Renal Stones

    MacLennan, S., Wiseman, O. J., Smith, D., Starr, K., Aucott, L., Hernández, R. A., Manson, P., Thomas, R., Clark, C. T., MacLennan, G., McRae, D., Bell, V., Cotton, S., Gall, Z., Turney, B., McClinton, S.
    European Urology
    Contributions to Journals: Articles

  • Intravenous Lidocaine for Gut Function Recovery in Colonic Surgery: A Health Economic Evaluation of the ALLEGRO Randomised Clinical Trial

    Atter, M., Stoddart, A., Cotton, S., Vadiveloo, T., Innes, K., Balfour, A., Arnott, R., Aucott, L., Batham, Z., Foo, I., MacLennan, G., Nimmo, S., Speake, D., Norrie, J., Paterson, H.
    BMJ Open, vol. 15, no. 2, e088298
    Contributions to Journals: Articles

  • The PUrE Randomised Controlled Trial (RCT) 1:: Clinical and cost-effectiveness of Flexible Ureterorenoscopy and Extracorporeal Shockwave Lithotripsy for lower pole stones ≤10mm.

    Wiseman, O. J., Smith, D., Starr, K., Aucott, L., Hernández, R. A., Thomas, R., MacLennan, S., Clark, C. T., MacLennan, G., McRae, D., Bell, V., Cotton, S., Gall, Z., Turney, B., McClinton, S.
    European Urology
    Contributions to Journals: Articles

  • ICANEQUAL multi-stakeholder partnership: Reducing inequalities in liver cancer (HCC) diagnosis, treatment and care across the UK

    Tripathee, S., Treweek, S., Van Hemelrijck, M., Ross, P., Watson, V., MacLennan, G., Guntupalli, A., Adams, J., Majmudar, B., Murchie, P., Bekheit, M., MacLennan, S.
    NIHR Open Research, vol. 5, no. 5
    Contributions to Journals: Articles

  • Intravenous lidocaine for gut function recovery in colonic surgery: A Randomized Clinical Trial

    Paterson, H., Vadiveloo, T., Innes, K., Balfour, A., Atter, M., Cotton, S., Stoddart, A., Arnott, R., Aucott, L., Batham, Z., Foo, I., MacLennan, G., Nimmo, S., Speake, D., Norrie, J.
    JAMA, vol. 333, no. 1, pp. 39-48
    Contributions to Journals: Articles

  • Complexity of Trials on Pain Management in Acute Pancreatitis: An Ongoing Challenge

    Kamarajah, S. K., Maclennan, G., Pandanaboyana, S.
    Clinical Gastroenterology and Hepatology, vol. 23, no. 1
    Contributions to Journals: Letters

  • Laparoscopic cholecystectomy versus conservative management for uncomplicated symptomatic gallstones: economic evaluation based on the C-GALL trial

    Hernández, R. A., Ahmed, I., Edwards, K., Hudson, J., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B. L., MacLennan, G., Murchie, P., Ramsay, C.
    British Journal of Surgery, vol. 112, no. 1, znae293
    Contributions to Journals: Articles

  • A feasibility randomized controlled trial of an individually delivered, peer support intervention to reduce the impact of psychosis stigma and discrimination for people with psychosis: the let's talk study

    Pyle, M., Corrigan, P. W., Wood, L., Pilling, S., Murphy, E., Macafee, G., Kelly, K., Byrne, R., Dunbar, E., Jones, E., Hudson, J., Jones, W., Hazzard, R., Larson, J. E., MacLennan, G., Swingler, J., Peters, S., Morrison, A. P., Let's Talk Research Group
    Psychological Medicine, vol. 54, no. 16, pp. 1-12
    Contributions to Journals: Articles

  • A randomised, double-blind placebo controlled trial of the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease

    Devereux, G., Cotton, S., Nath, M., McMeekin, N., Campbell, K., Chaudhuri, R., Choudhury, G., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J., Lee, A., MacLennan, G., Morice, A., Norrie, J., Price, D., Short, P., Vestbo, J., Walker, P., Wedzicha, J. A., Wilson, A., Wu, O., Lipworth, B. J.
    Health Technology Assessment
    Contributions to Journals: Articles

  • CATHETER II: a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Dimitropoulos, K., Evans, S., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., Murchie, P., Myint, P. K., N'Dow, J., Paterson, C., Powell, K., Scotland, G., Thiruchelvam, N., Young, A., Cotton, S., Norrie, J., MacLennan, G.
    BMJ Open, vol. 14, no. 12, e087203
    Contributions to Journals: Articles

  • Clinical and cost-effectiveness of parenting intervention for mothers experiencing psychosocial stress: insights from the early closure of the Mellow Babies RCT

    Thompson, L., Tanner, J., Breckons, M., Young, N., Ternent, L., Vadiveloo, T., Wilson, P., Wight, D., Marryat, L., McGowan, I., MacLennan, G., MacBeth, A., McTaggart, J., Allison, T., Norrie, J.
    Public Health Research, vol. 12, no. 17
    Contributions to Journals: Articles

  • Which glaucoma patients should be monitored at home and exploration of clinician perceptions on home monitoring? a survey of glaucoma specialists in the UK

    Alagappan, U., Stewart, C., Azuara-Blanco, A., King, A. J., Tatham, A., Hernández, R., MacLennan, G., Shotton, D., Forrest, M., Gillies, K.
    BMJ Open, vol. 14, no. 11, pp. e080873
    Contributions to Journals: Articles

  • CATHETER II, a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Cotton, S., Norrie, J., MacLennan, G., Team, C. I.
    The International Continence Society
    Contributions to Conferences: Posters

  • RCT comparing the clinical and cost effectiveness of various catheter washout policies

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Cotton, S., Norrie, J., MacLennan, G., Team, C. I.
    RCOG World Congress 2024
    Contributions to Conferences: Posters

  • Patient and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Cotton, S., Norrie, J., MacLennan, G.
    RCOG World Congress 2024, pp. 171
    Contributions to Journals: Abstracts

  • The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: The (UK-REBOA) multicentre RCT

    Jansen, J. O., Hudson, J., Kennedy, C., Cochran, C., Maclennan, G., Gillies, K., Lendrum, R., Sadek, S., Boyers, D., Ferry, G., Lawrie, L., Nath, M., Cotton, S., Wileman, S., Forrest, M., Brohi, K., Harris, T., Lecky, F., Moran, C., Morrison, J. J., Norrie, J., Paterson, A., Tai, N., Welch, N., Campbell, M. K., UK-REBOA Study Group
    Health Technology Assessment, vol. 28, no. 54
    Contributions to Journals: Articles

  • Patient and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial

    Tripathee, S., Abdel-Fattah, M., Johnson, D., Constable, L., Cotton, S., MacLennan, G., Norrie, J., Omar, M. I., MacLennan, S.
    The International Continence Society
    Contributions to Conferences: Posters

  • Public perspective on potential treatment intervention harm in clinical trials-terminology and communication

    Phillips, R., Bi, D., Goulão, B., Miller, M., El-Askary, M., Fagbemi, O., Freeborn, C., Giammetta, M., El Masri, N., Flockhart, P., Kumar, M., Melvin, M., Murray, D., Myhill, A., Saeid, L., Thomas, S., MacLennan, G., Cornelius, V.
    Trials, vol. 25, no. 1, 573
    Contributions to Journals: Articles

  • Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study

    Stewart, C., Wu, H., Alagappan, U., Azuara-Blanco, A., King, A. J., Tatham, A. J., Hernández, R., Lowe, B., Shotton, D., Appiah, N., Coffey, T., Vadiveloo, T., MacLennan, G., Gillies, K.
    Health technology assessment (Winchester, England), vol. 28, no. 44, pp. 1-163
    Contributions to Journals: Articles

  • Text Messages With Financial Incentives for Men With Obesity: A Randomized Clinical Trial

    Hoddinott, P., O'Dolan, C., Macaulay, L., Dombrowski, S. U., Swingler, J., Cotton, S., Avenell, A., Getaneh, A. M., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M., Torrens, C., Turner, K., van der Pol, M., MacLennan, G.
    JAMA, vol. 332, no. 1, pp. 31-40
    Contributions to Journals: Articles

  • Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    King, A. J., Hudson, J., Azuara-Blanco, A., Burr, J., Kernohant, A., Homer, T., Shabaninejad, H., Sparrow, J. M., Garway-Heath, D., Barton, K., Norrie, J., Davidson, T., Vale, L., MacLennan, G., TAGS Study Group
    Ophthalmology, vol. 131, no. 7, pp. 759-770
    Contributions to Journals: Articles
Show 10 | 25 | 50 | 100 results per page

Refine

Books and Reports

Chapters in Books, Reports and Conference Proceedings

Contributions to Conferences

Contributions to Journals

Update