Director (CHaRT)
- About
-
- Email Address
- g.maclennan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438147
- Office Address
Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
Qualifications
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
- Research
-
Research Overview
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
- Teaching
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Teaching Responsibilities
I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.
- Publications
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Page 4 of 10 Results 76 to 100 of 250
Survey on ureTEric draiNage post uncomplicaTed ureteroscopy (STENT)
BJUI Compass, vol. 2, no. 2, pp. 115-125Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/bco2.48
- [ONLINE] View publication in Scopus
Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial)
European Urology, vol. 78, no. 4, pp. 572-580Contributions to Journals: ArticlesAntipsychotic medication versus psychological intervention versus a combination of both in adolescents with first-episode psychosis (MAPS): a multicentre, three-arm, randomised controlled pilot and feasibility study
The lancet. Psychiatry, vol. 7, no. 9, pp. 788-800Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S2215-0366(20)30248-0
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14938/1/PIIS2215036620302480.pdf
- [ONLINE] View publication in Scopus
Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery: randomised controlled trial (PROSPECT)
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 127, no. 8, pp. 1002-1013Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/1471-0528.16197
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14488/1/Glazener_etal_BJOG_Mesh_inlay_VOR.pdf
- [ONLINE] View publication in Scopus
The clinical and cost effectiveness of surgical interventions for stones in the lower pole of the kidney: the percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole kidney stones randomised controlled trial (PUrE RCT) protocol
Trials, vol. 21, 479Contributions to Journals: ArticlesTotal versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT
Health technology assessment (Winchester, England), vol. 24, no. 20, pp. 1-98Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta24200
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14438/1/3032379.pdf
- [ONLINE] View publication in Scopus
Baseline Characteristics of Participants in the Treatment of Advanced Glaucoma Study: A Multicenter Randomized Controlled Trial
American Journal of Ophthalmology, vol. 213, pp. 186-194Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajo.2020.01.026
- [ONLINE] View publication in Scopus
Surgical treatments for women with stress urinary incontinence: a systematic review of economic evidence
Systematic reviews , vol. 9, 85Contributions to Journals: ArticlesEffect of hands-on interprofessional simulation training for local emergencies in Scotland: the THISTLE stepped-wedge design randomised controlled trial
BMJ Quality & Safety, vol. 29, no. 2, pp. 122-134Contributions to Journals: ArticlesEarly signs monitoring to prevent relapse in psychosis and promote well-being, engagement, and recovery: Protocol for a feasibility cluster randomized controlled trial harnessing mobile phone technology blended with peer support
JMIR Research Protocols, vol. 9, no. 1, pp. e15058Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2196/15058
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14678/1/document.pdf
- [ONLINE] View publication in Scopus
Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis
BMJ Open, vol. 10, no. 6, 035555Contributions to Journals: ArticlesIDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study
International Journal of Surgery Protocols, vol. 21, pp. 8-12Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.isjp.2020.02.002
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14328/1/1_s2.0_S246835742030005X_main.pdf
- [ONLINE] View publication in Scopus
ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial
Trials, vol. 20, 723Contributions to Journals: ArticlesPractical help for specifying the target difference in sample size calculations for RCTs: The DELTA2 five-stage study, including a workshop
Health Technology Assessment, vol. 23, no. 60Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta23600
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13466/1/HTA_3030850_VOR.pdf
- [ONLINE] View publication in Scopus
Methods to deal with missing data in area under the curve outcomes in randomised controlled trials: the OPEN trial case
5th International Clinical Trials Methodology Conference, pp. 141-141Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1186/s13063-019-3688-6
Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial
The Lancet, vol. 394, no. 10207, pp. 1425-1436Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(19)31790-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13243/1/Cooper_etal_Lancet_Laparoscopic_supracervical_VOR.pdf
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/laparoscopic-supracervical-hysterectomy-versus-endometrial-ablation-for-women-with-heavy-menstrual-bleeding-health(20b3fd84-6e08-4603-beaf-87c88732a17a).html
- [ONLINE] View publication in Scopus
Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins
The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1056/NEJMoa1805186
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13810/1/NEJMFive_year_outcomes_Brittenden_at_al_VoR.pdf
- [ONLINE] Publisher permissions
- [ONLINE] http://www.ncbi.nlm.nih.gov/pubmed/31483962
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Photodynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A study protocol for a randomised trial of clinical and cost-effectiveness
BMJ Open, vol. 9, no. 9, e22268Contributions to Journals: ArticlesThe clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial
The Lancet, vol. 394, no. 10200, pp. 746-756Contributions to Journals: ArticlesStudy protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS)
Trials, vol. 20, 395Contributions to Journals: ArticlesSurgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials
BMJ, vol. 365, l1842Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.l1842
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12387/1/bmj.l1842.full.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] http://www.bmj.com/lookup/doi/10.1136/bmj.l1842
- [ONLINE] View publication in Mendeley
Supporting Harm Reduction through Peer Support (SHARPS): Testing the feasibility and acceptability of a peer-delivered, relational intervention for people with problem substance use who are homeless, to improve health outcomes, quality of life and social functioning and reduce harms: Study protocol
Pilot and Feasibility Studies, vol. 5, 64Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s40814-019-0447-0
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14966/1/document_1_.pdf
- [ONLINE] View publication in Scopus
Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation
Health Technology Assessment, vol. 23, no. 14, pp. 1-306Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta23140
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12177/1/Surgical_treatments_for_women_with_stress_urinary_incontinence.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
- [ONLINE] Pubmed Publication
399 - Surgical treatment for recurrent bulbar urethral stricture: A randomised open label superiority trial of open urethroplasty versus endoscopic urethrotomy (The OPEN Trial): Abstracts EAU19 – 34th Annual EAU Congress
European Urology Supplements, vol. 18, no. 1, pp. e523Contributions to Journals: ArticlesCognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT
Health Technology Assessment, vol. 23, no. 7, pp. 1-144Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta23070
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12098/1/HTA_Report_3028539.pdf
- [ONLINE] View publication in Scopus