Professor Graeme MacLennan
Director (CHaRT)
- About
-
- Email Address
- g.maclennan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438147
- Office Address
Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
Qualifications
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
- Research
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Research Overview
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
- Teaching
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Teaching Responsibilities
I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.
- Publications
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Single-Incision Mini-Slings for Stress Urinary Incontinence in Women
The New England Journal of Medicine, vol. 386, no. 13, pp. 1230-1243Contributions to Journals: ArticlesShockwave lithotripsy compared with ureteroscopic stone treatment for adults with ureteric stones: the TISU non-inferiority RCT
Health technology assessment (Winchester, England), vol. 26, no. 19, pp. 1-70Contributions to Journals: ArticlesAssessing the feasibility, acceptability and accessibility of a peer-delivered intervention to reduce harm and improve the well-being of people who experience homelessness with problem substance use: the SHARPS study
Harm Reduction Journal, vol. 19, 10Contributions to Journals: ArticlesA peer-delivered intervention to reduce harm and improve the well-being of homeless people with problem substance use: the SHARPS feasibility mixed-methods study
Health technology assessment (Winchester, England), vol. 26, no. 14, pp. 1-128Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/WVVL4786
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/18607/1/Parkes_et_al_A_Peer_delivered_NIHR_vor.pdf
- [ONLINE] View publication in Scopus
The ALLEGRO trial: a placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgery
Trials, vol. 23, no. 1, 84Contributions to Journals: ArticlesEye Movement Patterns Can Distinguish Schizophrenia From the Major Affective Disorders and Healthy Control Subjects
Schizophrenia Bulletin Open, vol. 3, no. 1, sgac032Contributions to Journals: ArticlesHow common are complications following polypropylene mesh, biological xenograft and native tissue surgery for pelvic organ prolapse?: A secondary analysis from the PROSPECT trial
BJOG: An International Journal of Obstetrics and Gynaecology, vol. 128, no. 13, pp. 2180-2189Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/1471-0528.16897
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/17640/1/Reld_etal_BJOG_How_Common_Are_VoR.pdf
- [ONLINE] View publication in Scopus
Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT
Books and Reports: Other ReportsPrimary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT
Health Technology Assessment, vol. 25, no. 72, pp. i-158Contributions to Journals: ArticlesFemale Urgency, Trial of Urodynamics as Routine Evaluation (FUTURE study): a superiority randomised clinical trial to evaluate the effectiveness and cost-effectiveness of invasive urodynamic investigations in management of women with refractory overactive bladder symptoms
Trials, vol. 22, no. 1, 745Contributions to Journals: ArticlesThe IDENTIFY Study: The Investigation and Detection of Urological Neoplasia in Patients Referred with Suspected Urinary Tract Cancer; A multicentre observational study
BJU International, vol. 128, no. 4, pp. 440-450Contributions to Journals: ArticlesWhy trials lose participants: a multi-trial investigation of participants’ perspectives using the theoretical domains framework
Journal of Clinical Epidemiology, vol. 137, pp. P1-13Contributions to Journals: ArticlesSelective Caries Removal in Permanent Teeth (SCRiPT) for the treatment of deep carious lesions: a randomised controlled clinical trial in primary care
BMC Oral Health, vol. 21, 336Contributions to Journals: ArticlesHave you had bleeding from your gums?: Self-report to Identify giNGival inflammation (The SING diagnostic accuracy and diagnostic model development study)
Journal of Journal of Clinical Periodontology, vol. 48, no. 7, pp. 919-928Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/jcpe.13455
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16648/1/goulao_etal_have_you_had_VOR.pdf
Shockwave Lithotripsy Versus Ureteroscopic Treatment as Therapeutic Interventions for Stones of the Ureter (TISU): A Multicentre Randomised Controlled Non-inferiority Trial
European Urology, vol. 80, no. 1, pp. 46-54Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.eururo.2021.02.044
The arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: The STOPPIT 2 RCT
NIHR Health Technology Assessment programme. 94 pagesBooks and Reports: Other Reports- [ONLINE] DOI: https://doi.org/10.3310/hta25440
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/17001/1/Norman_etal_HTA_The_Arabin_pessary_VOR.pdf
- [ONLINE] View publication in Scopus
Outcomes of a non-inferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER)
European Urology, vol. 79, no. 6, pp. 812-823Contributions to Journals: ArticlesTISU (Therepeutic Intervention for Stones in the Ureter): ESWL versus Ureteroscopy, a multicentre RCT
European Urology, vol. 79, no. S1, pp. S390-S390Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1016/S0302-2838(21)00660-6
Tibial nerve stimulation compared with sham to reduce incontinence in care home residents: ELECTRIC RCT
Health technology assessment (Winchester, England), vol. 25, no. 41, pp. 1-109Contributions to Journals: ArticlesPrimary trabeculectomy for advanced glaucoma: pragmatic multicentre randomised controlled trial (TAGS)
BMJ, vol. 373, n1014Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.n1014
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16479/1/bmj-373-bmj-n1014.pdf
Equity of access to critical care services in Scotland: A Bayesian spatial analysis
Journal of the Intensive Care Society, vol. 22, no. 2, pp. 127-135Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1177/1751143720914462
- [ONLINE] View publication in Scopus
Evaluation of the Arabin cervical pessary for prevention of preterm birth in women with a twin pregnancy and short cervix (STOPPIT-2): An open-label randomised trial and updated meta-analysis
PLoS Medicine, vol. 18, no. 3, e1003506Contributions to Journals: ArticlesProtocol for a randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones (C-Gall trial)
BMJ Open, vol. 11, no. 3, e039781Contributions to Journals: Articles- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/33766835/
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2020-039781
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16202/1/Ahmed_etal_Protocol_for_randomised_VOR.pdf
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/protocol-for-a-randomised-controlled-trial-comparing-laparoscopic-cholecystectomy-with-observationconservative-management-for-preventing-recurrent-symptoms-and-complications-in-adults-with-uncomplica(a66000bc-ddf4-4d6b-9167-7efd1556eace).html
Psychological intervention, antipsychotic medication or a combined treatment for adolescents with a first episode of psychosis: the MAPS feasibility three-arm RCT
Health technology assessment (Winchester, England), vol. 25, no. 4, pp. 1-124Contributions to Journals: ArticlesOpen urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT
Contributions to Journals: Registered Reports- [ONLINE] DOI: https://doi.org/10.3310/hta24610
