![Dr Wenbo Zhan Dr Wenbo Zhan](/img/200x200/staffpages/uploads/s01wz9/Untitled-4.jpg)
Lecturer
- About
-
- Email Address
- w.zhan@abdn.ac.uk
- Office Address
R353, Fraser Noble Building
School of Engineering
King's College
University of Aberdeen
Aberdeen AB24 3UE, UK
- School/Department
- School of Engineering
Biography
Wenbo Zhan is a Lecturer in Biological Engineering in the School of Engineering. He received his undergraduate degrees from Xi’an Jiaotong University in 2008 and a master degree from Harbin Institute of Technology in 2010. He graduated from Imperial College London with his PhD degree in 2014 and then worked as a project consultant at Imperial College London and a postdoctoral research fellow at the National University of Singapore until 2016. Prior to joining the University of Aberdeen in 2019, he was a research associate at Imperial College London.
Qualifications
- PhD Chemical Engineering2014 - Imperial College London
- MSc Thermal Energy and Power Engineering2010 - Harbin Institute of Technology
- BEng Thermal Energy and Power Engineering2008 - Xi'an Jiaotong University
- BEc Finance2008 - Xi'an Jiaotong Univerisity
Memberships and Affiliations
- Internal Memberships
-
- Overall coordinator of the School MSc individual projects
- Deputy coordinator of MSc Biomedical Engineering programme
- Member of School Postgraduate Education Committee
- External Memberships
-
- Editorial Advisory Board member of Pharmaceutical Research, 12/2022-present
- Research
-
Research Overview
Wenbo Zhan's research centres on biological engineering and bioprocessing, with a particular focus on the biomechanics and transport processes in biological and physiological systems.
- Multiscale modelling of drug delivery processes
- Soft tissue deformation
- Image-based analysis of cardiovascular fluid mechanics
Funding and Grants
- Injectable thermosensitive hydrogel for controlled drug release targeting resected glioblastoma, The Royal Society, PI, 01/10/2024 - 30/09/2025
- HyWay: Hydrogen production from waste, European Union & EPSRC, Co-I, 15/04/2024 - 14/04/2028
- Evaluation and optimisation of thermosensitive hydrogel for controllable drug delivery against brain tumour, The Royal Society of Edinburgh, PI, 01/02/2023 - 30/09/2023
- Image-based modelling and optimisation of convection-enhanced delivery for combination therapy against heterogeneous human brain tumour, The Royal Society, PI, 12/08/2022 - 11/08/2024
- Gender differences in sex hormone transport in abdominal aortic aneurysm, The Royal Society, PI, 31/03/2022 - 30/03/2024
- Optimisation of infusion catheter posture for improving convection-enhanced drug delivery to brain cancer, Children's Brain Tumour Drug Delivery Consortium, Children with Cancer UK, PI, 01/03/2022 - 30/09/2022
- Novel nanoparticle-embedded membranes for long-term bioactive SARS-CoV2 prevention, Grampian University Hospitals NHS Trust, Co-I, 01/04/2021 - 31/03/2023
- Multifunctional liquid crystals stabilised by hydrogen-bounding and their integration in new devices for energy harvesting, conversion and storage, The Royal Society of Edinburgh, Co-I, 23/10/2020 - 30/12/2021
- Teaching
-
Teaching Responsibilities
Programme
MSc Biomedical Engineering programme
Course coordinator
- EG555L - Modelling of Biological Systems
- EG20H7 - Fluid Mechanics for Civil Engineers 1
- EG30H3 - Fluid Mechanics for Civil Engineers 2
- EG555N,EG59F1,EG59F2,EG59M2 - MSc Individual Project (all MSc programmes)
Course contributor
- EG555J - Research Methods for Bioengineers
- EG4578 - Group Design Project (Chemical Engineering)
Previous course
- EG504Q - Introduction to Engineering for Life Scientists
- Publications
-
Page 1 of 1 Results 1 to 84 of 84
On the Characteristics of Fluid Transport within Reconstructed Brain Tumours at Pore-Scale
Contributions to Conferences: Oral PresentationsMicrostructure-based Modelling Reveals Macroscale Transport Property of Brain Tissues
Contributions to Conferences: Oral Presentations- [ONLINE] Talk on Conference website
Image-based predictive modelling frameworks for personalised drug delivery in cancer therapy
Journal of Controlled Release, vol. 370, pp. 721-746Contributions to Journals: ArticlesA Computational Framework for Mechanically Controlled Brain Drug Delivery
Contributions to Conferences: Oral PresentationsA novel regional-minima image segmentation method for fluid transport simulations in unresolved rock images
Water Resources Research, vol. 60, no. 6, e2023WR036855Contributions to Journals: ArticlesPore-Scale Analysis of Fluid Transport in Different Grades of Brain Tumours Considering the Effect of Extracellular Matrix
Interpore2024Contributions to Conferences: Posters- [ONLINE] Book of abstracts
Pore-Scale Modelling of Non-Linear Rock Deformation under Low Stress Ranges
Contributions to Conferences: Oral Presentations- [ONLINE] Book of Abstracts
Numerical simulation of transdermal delivery of drug nanocarriers using solid microneedles and medicated adhesive patch
International Journal of Heat and Mass Transfer, vol. 223, 125291Contributions to Journals: ArticlesInvestigating Charged Nanoparticles Diffusion in Brain Tumour Microstructures at Pore Scale
Contributions to Conferences: Oral Presentations- [ONLINE] Conference programme
Elucidating the Effect of Zeta Potential and Particle Size on Nanoparticle Diffusion in Brain Tumours
29th Congress of the European Society of BiomechanicsContributions to Conferences: PostersRadiopharmaceutical transport in solid tumors via a 3-dimensional image-based spatiotemporal model
npj Systems Biology and Applications, vol. 10, 39Contributions to Journals: ArticlesDecoding the effect of different tumor heterogeneities on thermosensitive liposome drug delivery during radiofrequency ablation: A novel heat and mass transfer perspective
International Communications in Heat and Mass Transfer, vol. 153, 107390Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.icheatmasstransfer.2024.107390
A comprehensive review on modeling aspects of infusion-based drug delivery in the brain
Acta BiomaterialiaContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.actbio.2024.07.015
Effect of infusion posture on convection-enhanced drug delivery to anisotropic tissue
Journal of the Royal Society InterfaceContributions to Journals: ArticlesMathematical modelling of microneedle-mediated transdermal delivery of drug nanocarriers into skin tissue and circulatory system
Journal of Controlled Release, vol. 360, pp. 447-467Contributions to Journals: ArticlesHighlighting the effect of heterogeneous blood perfusion on radio-frequency ablation of human brain tumors: An image-based numerical investigation
International Journal of Thermal Sciences, vol. 189, 108283Contributions to Journals: Articles177Lu-PSMA-617 Transport in Solid Tumors via a 3D Image-based Spatio-temporal Model
Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2023, pp. P811Contributions to Journals: AbstractsEffect of extracellular matrix on tissue hydraulic permeability of the brain tumour
36th Scottish Fluid Mechanics Meeting, pp. 39-40Contributions to Conferences: PostersA novel local-minima 3D image segmentation method for fluid flow in low-resolution porous material images
Contributions to Conferences: Oral PresentationsLinking fluid-axons interactions to the macroscopic fluid transport properties of the brain
Acta Biomaterialia, vol. 160, pp. 152-163Contributions to Journals: ArticlesMultiphysics Simulation in Drug Development and Delivery
Pharmaceutical Research, vol. 40, pp. 611–613Contributions to Journals: EditorialsMathematical Optimisation of Magnetic Nanoparticle Diffusion in the Brain White Matter
International Journal of Molecular Sciences, vol. 24, no. 3, 2534Contributions to Journals: ArticlesIn-situ vaccination using dual responsive organelle targeted nanoreactors
Biomaterials, vol. 290, 121843Contributions to Journals: ArticlesPore-scale modelling of elastic properties in hydrate-bearing sediments using 4-D synchrotron radiation imaging
Marine and Petroleum Geology, vol. 145, 105864Contributions to Journals: ArticlesConvection-Enhanced Delivery of Antiangiogenic Drugs and Liposomal Cytotoxic Drugs to Heterogeneous Brain Tumor for Combination Therapy
Cancers, vol. 14, no. 17, 4177Contributions to Journals: ArticlesOn the microstructurally driven heterogeneous response of brain white matter to drug infusion pressure
Biomechanics and Modeling in Mechanobiology, vol. 21, pp. 1299–1316Contributions to Journals: ArticlesEffects of tissue hydraulic permeability on intracerebral transport of interstitial fluid and nanoparticle-encapsulated drugs upon convection-enhanced delivery
9th World Congress of Biomechanics, pp. O-20123Contributions to Conferences: AbstractsNumerical modelling of nanoparticle-mediated drug delivery across blood-brain barrier using focused ultrasound
9th World Congress of Biomechanics, pp. P-2010Contributions to Conferences: Abstracts- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/18954/1/P_2010.pdf
Effect of tissue permeability on drug transport in brain tumour after pressure-driven infusion
Contributions to Conferences: Oral Presentations- [ONLINE] https://sfmm2022.org
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour
Pharmaceutical Research, vol. 39, no. 5, pp. 877-892Contributions to Journals: ArticlesEffect of particle size and surface charge on nanoparticles diffusion in the brain white matter
Pharmaceutical Research, vol. 39, pp. 767–781Contributions to Journals: ArticlesMathematical modelling of nanoparticle-mediated topical drug delivery to skin tissue
International Journal of Pharmaceutics, vol. 611, 121322Contributions to Journals: ArticlesConvection Enhanced Delivery of Light Responsive Antigen Capturing Oxygen Generators for Chemo-Phototherapy Triggered Adaptive Immunity
AIChE 2021Contributions to Conferences: AbstractsAnti-angiogenic effect on convection-enhanced delivery of cytotoxic drugs
BioMedEng21Contributions to Conferences: AbstractsEffect of brain tissue anisotropy on convection-enhanced delivery of nanoparticles encapsulated carmustine
BioMedEng21Contributions to Conferences: Abstracts- [ONLINE] Conference Book of Abstracts
- [ONLINE] Conference site
Convection enhanced delivery of light responsive antigen capturing oxygen generators for chemo-phototherapy triggered adaptive immunity
Biomaterials, vol. 275, 120974Contributions to Journals: ArticlesCharacterization of Transport Properties of Drugs in Brain Tissue Using Computational Fluid Dynamics
Contributions to Conferences: Oral PresentationsParticle velocity measurement of binary mixtures in the riser of a circulating fluidized bed by the combined use of electrostatic sensing and high-speed imaging
Petroleum Science, vol. 17, no. 4, pp. 1159-1170Contributions to Journals: ArticlesEnhanced penetration of pro-apoptotic and anti-angiogenic micellar nanoprobe in 3D multicellular spheroids for chemophototherapy
Journal of Controlled Release, vol. 323, pp. 502-518Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jconrel.2020.05.005
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16380/1/Mozhi_etal_JCR_Enhanced_AAM.pdf
- [ONLINE] View publication in Scopus
A pilot study of aortic hemodynamics before and after thoracic endovascular repair with a double-branched endograft
Medicine in Novel Technology and Devices, vol. 4, 100027Contributions to Journals: ArticlesEffects of Focused-Ultrasound-and-Microbubble-Induced Blood-Brain Barrier Disruption on Drug Transport under Liposome-Mediated Delivery in Brain Tumour: a Pilot Numerical Simulation Study
Pharmaceutics, vol. 12, no. 1, 69Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3390/pharmaceutics12010069
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13664/1/WZhan_Pharmaceutics_2020.pdf
- [ONLINE] View publication in Scopus
Convection enhanced delivery of anti-angiogenic and cytotoxic agents in combination therapy against brain tumour
European Journal of Pharmaceutical Sciences, vol. 141, 105094Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ejps.2019.105094
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15228/1/Zhan_EurJPharmSci_AAM.pdf
- [ONLINE] View publication in Scopus
Convection Enhanced Delivery of Light Responsive Antigen Capturing Oxygen Generators for Photoimmunotherapy of Hypoxic Tumors
Contributions to Conferences: PapersEffect of Enhanced Cerebrospinal Fluid Flow on Drug Penetration in Convection Enhanced Delivery
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsDevelopment of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue
Journal of Pharmaceutical Sciences, vol. 108, no. 5, pp. 1736-1745Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.xphs.2018.12.002
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation
International Journal of Pharmaceutics, vol. 557, pp. 280-292Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ijpharm.2018.12.065
- [ONLINE] View publication in Scopus
Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery
Drug Delivery, vol. 26, no. 1, pp. 773-781Contributions to Journals: ArticlesNeurosurgical Convection Enhanced Drug Delivery: Experiments and Modelling
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsOptimising Nanoparticle Property and Treatment Regimen for Improving Convection Enhanced Delivery of Doxorubicin to Brain Tumour
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsTowards a multiphysics modelling framework for thermosensitive liposomal drug delivery to solid tumour combined with focused ultrasound hyperthermia
Biophysics Reports, vol. 5, no. 1, pp. 43-59Contributions to Journals: ArticlesTransport of Chemotherapeutic Agents in Anisotropic Tissue under Convection Enhanced Delivery for Localised Treatment
Contributions to Conferences: PapersConvection enhanced delivery of liposome encapsulated doxorubicin for brain tumour therapy
Journal of Controlled Release, vol. 285, pp. 212-229Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jconrel.2018.07.006
Computational modelling of drug delivery to solid tumour: Understanding the interplay between chemotherapeutics and biological system for optimised delivery systems
Advanced Drug Delivery Reviews, vol. 132, pp. 81-103Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.addr.2018.07.013
- [ONLINE] Deposit in Imperial College repository
Towards an Optimized Path Planner for the EDEN2020 Neurosurgical Steerable Needle
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsConvection enhanced delivery of chemotherapeutic drugs into brain tumour
Journal of Controlled Release, vol. 271, pp. 74-87Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jconrel.2017.12.020
3D-Bioprinting and Micro-/Nano-Technology: Emerging Technologies in Biomedical Sciences (Preface)
Advanced Drug Delivery Reviews, vol. 132, pp. 1-2Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.addr.2018.09.007
A Multiphysics Model for Focused Ultrasound Activated Thermosentitive Liposome Drug Delivery to Tumour
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsA Pilot Study on Aortic Flow before and after Endovascular Repair with a Novel Branched Stent-Graft for Thoracic Aortic Aneurysm
Contributions to Conferences: PapersMathematical Modelling of Cerebral Infusion of Nanoparticle Encapsulated Anticancer Drugs for Brain Tumour Therapy
Contributions to Conferences: PapersMicromechanical Modelling of Brain White Matter
Contributions to Conferences: PapersNumerical Simulation of Convection Enhanced Delivery of Nano Drug Carriers into Brain Tumour
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsNumerical Study on Cerebral Infusion Induced Backflow for Convection Enhanced Delivery
Contributions to Conferences: PapersThe effect of tumour size on drug transport and uptake in 3-D tumour models reconstructed from magnetic resonance images
PloS ONE, vol. 12, no. 2, e0172276Contributions to Journals: ArticlesMathematical Modelling of Convection Enhanced Delivery of Carmustine and Paclitaxel for Brain Tumour Therapy
Pharmaceutical Research, vol. 34, pp. 860-873Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s11095-017-2114-6
Model for Focused Ultrasound-mediated Thermosentitive Liposome Drug Delivery to Tumour
Contributions to Conferences: PapersNumerical Simulation of Thermosensitive Liposome-mediated Delivery of Doxorubicin to Solid Tumour under High Intensity Focused Ultrasound Heating
Contributions to Conferences: PapersNumerical Study on Convection Enhanced Delivery of Anticancer Drugs into Brain Tumour
Contributions to Conferences: PapersA Dual Tracer 18F-FCH/18F-FDG PET Imaging of an Orthotopic Brain Tumor Xenograft Model
PloS ONE, vol. 11, no. 2, e0148123Contributions to Journals: ArticlesNumerical Simulation of Downdraft Biomass Gasifier: Influence of Structure Designs Using CFD Simulation
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsNumerical Study on the Hydrodynamics Behaviour in Bubbling Fluidized Bed for Sewage Sludge Gasification
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsThe Effect of Infusion Position on Convection-Enhanced Delivery of Anticancer Drugs to Remnant Brain Tumour after Surgery
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsDrug Delivery to Solid Tumour with High Intensity Focused Ultrasound Heating
21st CLSS-UK Annual ConferenceContributions to Conferences: AbstractsEffect of heterogeneous microvasculature distribution on drug delivery to solid tumour
Journal of Physics D: Applied Physics, vol. 47, no. 47, 475401Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0022-3727/47/47/475401
Mathematical Modelling of Drug Transport and Uptake in a Realistic Model of Solid Tumour
Protein & Peptide Letters, vol. 21, no. 11, pp. 1146-1156Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2174/0929866521666140807115629
Simulation of HIFU Heating in Solid Tumour: Comparison of Different Temperature Control Modes
Contributions to Conferences: PapersA Mathematical Model for Thermosensitive Liposomal Delivery of Doxorubicin to Solid Tumour
Journal of Drug Delivery, vol. 2013, 172529Contributions to Journals: ArticlesComputational Study of Drug Transport in Realistic Models of Solid Tumour
Contributions to Conferences: PapersComputational Study of Drug Transport in Realistic Models of Solid Tumour
Chapters in Books, Reports and Conference Proceedings: Conference Proceedings- [ONLINE] https://www.aiche.org/conferences/aiche-annual-meeting/2012/proceeding/paper/312d-computational-study-drug-transport-realistic-models-solid-tumour
- [ONLINE] https://www.aiche.org/conferences/aiche-annual-meeting/2012/proceeding/session/simulation-based-engineering-and-science-biomedical-advances-i
Study on Hydrodynamic Characteristics in Liquid-Solid Reactor
Annual Meeting of Multiphase Flow.Chapters in Books, Reports and Conference Proceedings: Other ContributionsPrediction on immersed tubes erosion using two-fluid model in a bubbling fluidized bed
Chemical Engineering Science, vol. 64, no. 13, pp. 3072-3082Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ces.2009.03.033
Potential of Clean Development Mechanism Projects in Heilongjiang Province
Energy Conservation Technology, vol. 27, pp. 134-139Contributions to Journals: ArticlesStudy of the impact of the velocity inlet boundary condition to the bubbling fluidized bed
Kung Cheng Je Wu Li Hsueh Pao/Journal of Engineering Thermophysics, vol. 30, no. 5, pp. 789-792Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Simulation of Particle Segregation Behavior in Bubbling Fluidized Bed
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsStudy on the Impact of Friction Model on Hydrodynamic Behavior in Bubbling Fluidized Bed
Proceedings of Annual Meeting of Multiphase Flow.Chapters in Books, Reports and Conference Proceedings: Other Contributions