Medicine & Therapeutics

Credit Points

15

Course Coordinator

Prof. Gay M. Hawksworth

Pre-requisites

A degree or equivalent in Medicine, Pharmacy or a relevant science subject.

Overview

Lectures, tutorials and practical classes. Topics - absorption, distribution, metabolism and excretion of drugs. Human drug metabolism - cytochrome P450. Induction/inhibition of cytochrome P450. Identification of cytochrome P450 at an early stage in drug discovery. Pharmacogenetics of human drug metabolism - implication for drug safety in clinical practice. Mechanisms of drug induced toxiity: reactive metabolites; glutathoine conjugate-mediated toxicity; cytoprotective mechanisms; agents conferring protection against drug toxicity - clinical applications; mechanisms of cell death; apoptosis and necrosis. Target organ toxicity. Toxicology of specified organ systems. Clinical biochemistry of drug toxicity. Pathology of drug toxicity. Haematological indices of drug toxicity.

Structure

2 x 1 hour lectures per week.
2 x lab practicals during weeks 1-2.

Assessment

1 written exam paper (75%)
3 assignments for continuous assessment (25%)

Credit Points

10

Course Coordinator

Dr James McLay

Pre-requisites

A degree or equivalent at the prescribed standard in Medicine, Pharmacy or a relevant science subject.

Overview

Lectures and tutorials. Beta Adrenonreceptor Antagonists, Calcium Channel Antagonists, Lip Lowering Agents, Psychotic Illnesses and their treatment, Depression and its treatment, Angiotensin Converting Enzyme Inhibitors/Angiotensin Antagonists, Adverse Drug Reactions, Drug Interactions, Antibiotic Drugs used in the treatment of Asthma, Pharmacy Aspects of Safe Prescribing and Delivery of Drugs, Formulary Management, Drug Delivery Systems, Patient Compliance.

Structure

2x 1 or 1.5 hour lectures per week.
4 tutorials throughout the module.

Assessment

1 written exam (75%)
2 assignments for continuous assessment (25%)

Credit Points

5

Course Coordinator

Dr H M Wallace

Pre-requisites

A degree or equivalent qualification, at the prescibed standard in Medicine, Pharmacy or relevant Science

Overview

Lectures, seminars and workshops. Basic laboratory techniques, library facilities and presentation skills

Structure

3 x one hour lectures, 1x practical and 1x one-hour tutorial.

Assessment

Continuous assessment (100%)

Credit Points

50

Course Coordinator

Dr Lindsey Masson

Pre-requisites

The course is restricted to students on the MSc Human Nutrition and Metabolism, MSc Public Health Nutrition, or PG Diploma in Human Nutrition programmes. A second class honours degree or equivalent in biological sciences such as biochemistry, physiology, nutrition or medicine

Overview

Lectures, seminars and practical classes on dietary assessment, macronutrients, energy balance and metabolism, micronutrients, nutritional status and body composition, nutrition throughout the life cycle, and diet and disease

Structure

Approximately ten 1-hour lectures per week. Laboratory practical classes.

Assessment

Two 2 hour examininations (70%) and continuous assessment (30%)

Credit Points

20

Course Coordinator

Dr Heather M Wallace

Pre-requisites

A degree or equivalent qualification in Medicine, Pharmacy or relevant Science subject.

Overview

Lectures, seminars, tutorials and practical classes. Receptor pharmacology, immunopharmacology, cancer biology, molecular carcinogenesis, chemotherapy and ethics.

Structure

3 x 1 hour lectures per week.
1 tutorial or seminar per week.
1 lab practical throughout the course.

Assessment

1 written examination paper (80%).
2 assignments for continuous assessment (20%)

Credit Points

0

Course Coordinator

Dr Heather Wallace

Pre-requisites

A degree or equivalent qualification, at the prescribed standard in Medicine, Pharmacy or relevant Science subject (eg. Biochemistry, Biology, or Pharmacy).

Overview

Lectures, Basic Laboratory Techniques, Library Facilities and how to use them, Working in Teams.

Structure

1x 2-hour lecture once every two weeks.

Assessment

Credit Points

15

Course Coordinator

Dr Heather Wallace

Pre-requisites

N/A

Overview

Overview of receptor pharmacology
Cellular communication
Basic Immunology, immunopharmacology
Drug targeting and gene therapy
Cancer biology, chemotherapy, chemoprevention and drug resistance
Molecular carcinogenesis
Clinical indices of malignancy
Clinical therapy

Structure

3 x 1 hour lecture per week; 3 x tutorials; 1 x practical class

Assessment

1 formative essay, 1 practical report (10%), 1 essay, 1 x 1.5 hour written examination (65%)

Credit Points

20

Course Coordinator

Professor Gabrielle Hawksworth

Pre-requisites

IIi Honours degree in relevant discipline or MBChB

Overview

Human drug metabolism, induction/inhibition of metabolism, pharmacogenetics, molecular mechanisms of dtug-induced toxicity, developmental toxicology, immunotoxicology, neurotoxicology, risk assessment, regulation of pharmaceuticals/pesticides, mutagenesis, carcinogenesis, discovery toxicology, biomarkers in pre-clinical toxicology.

Structure

3/4 one-hour lectures, 1 one-hour tutorial per week; 3 all-day practicals.

Assessment

1 two-hour written examination (70%); continuous assessment (30%).

Credit Points

5

Course Coordinator

Dr J S McLay

Pre-requisites

MBChB or good Honours degree in Pharmacology, Pharmacy, Biochemistry or a related discipline.

Overview

Aspects described above for selected drug groups e.g. beta adrenoceptor antagonists, Ca channel antagonists, lip lowering drugs.
Adverse drug reactions.
Drug interactions.
Drug delivery systems.

Structure

Oral presentations by students to peers with supporting summaries and references collated and distributed by lecturer.

Assessment

1.5 hour written examination (75%); continuous assessment essay (25%).

Credit Points

20

Course Coordinator

Dr Heather Wallace

Pre-requisites

N/A

Overview

Basics of receptors, cancer biology and therapy, immunology, drug development and discovery, molecular biology, cancer treatment, cell signalling.

Structure

2 one-hour lectures per week, 4 tutorials, 1 six-hour practical class

Assessment

1 two-hour written examination, 1 presentation, 1 practical report, 1 formative essay, 1 essay

Credit Points

30

Course Coordinator

Dr Lindsey Masson

Pre-requisites

The course is restricted to students on the MSc Human Nutrition and Metabolism or PG Diploma in Human Nutrition programmes. The Human Nutrition core course (MT5007) and the Applied Statistics course (PU5005) are pre-requisites for this course.

Overview

Lectures, seminars and practical classes on epidemiology and study design, laboratory methods, gene-nutrient interactions, tracer methodology and clinical nutrition.

Structure

Approximately ten 1-hour lectures per week. Laboratory classes and clinical attachments.

Assessment

Two 2 hour examinations (70%) and continuous assessment (30%)

Credit Points

5

Course Coordinator

Dr MJ MacLeod

Pre-requisites

A degree or equivalent qualification, at the prescribed standard in Medicine, Pharmacy or a relevant Science subject (eg. Biochemistry, Biology or Pharmacy)

Co-requisites

None

Overview

The 1 week course will comprise lectures, tutorials and seminars. The curriculum will provide an in-depth look at pharmacovigilance using examples from both first and third world countries and will include detection of adverse drug reactions; causality assessment; prevention of adverse drug reactions including correct prescribing, prevention of drug errors and promotion of rational drug use; and communication of risk-benefit information to the general public.

Structure

5 x 1 hour lectures
5 tutorials/seminars

Assessment

1 assignment for continuous assessment (100%)

Credit Points

20

Course Coordinator

Dr James McLay

Pre-requisites

A degree or equivalent qualification at the prescribed standard in Medicine, Pharmacy or a relevant Science subject.

Overview

Impact or particular disease states with reference to the pathophysiology, epidemiology, economic cost and current drugs available. Rationale for further drug development and clinical trails. End point measurements. Drug trial design. Critical analysis of 'key' publications on the treatment of disease. Clinical guidelines. Selecting a limited list of medicines. Pharmacovigilance. Ethics. Development of a new medicinal compound from pharmacology to pharmaceutical product.

Structure

2 x 1.5 hour lectures per week.
4 tutorials throughout week 15-22.

Assessment

2 written exam paper (60%)
3 assignments for continuous assessment (40%)

Credit Points

10

Course Coordinator

Prof Gay M. Hawksworth

Pre-requisites

A degree or equivalent qualification, at the prescribed standard in Medicine, Pharmacy or a relevant Science subject.

Overview

Topics - Pharmacokinetic Principles, Applied Pharmacokinetics, Clinical Relevance of Pharmacokinetics, Therapeutic Drug Monitoring, Clinical Applications of Pharmacokinetics, Pharmacokinetics of Asprin (Practical).

Structure

3 x 1 hour lectures per week.
2 tutuorials during the module.
1 lab practical during the module.

Assessment

1 written exam (80%)
1 assignment for continuous assessment (20%)

Credit Points

5

Course Coordinator

Dr David Williams and Professor John Webster

Pre-requisites

N/A

Overview

Content will be dictated by the delivery of course material by available lecturers. The content would be broadly based on The Therapeutic aspects of Hypertension, stroke and Cardiovascular medicine. A clear line between the development of drugs in this therapeutic field and assessment of their safety will be emphasised.

Structure

7 one-hour lectures/tutorials (to be arranged).

Assessment

Continuous assessment essay/report (100%).

Credit Points

10

Course Coordinator

Professor Gabrielle Hawksworth

Pre-requisites

First Class Honours degree in relevant discipline or MBChB.

Overview

Introduction to pharmacokinetics, clinical pharmacokinetics, industrial pharmacokinetics, population kinetics, toxicokinetics.
Practical - aspirin pharmacokinetics and pharmacodynamics, using human volunteers.

Structure

3/4 one-hour lectures, 1 hour tutorial per week. One 2.5 day practical. Problem solving sessions using WinNonLin.

Assessment

One 2h 20min written exam (allows reading time for paper) (70%); continuous assessment (30%).

Credit Points

10

Course Coordinator

Dr Heather Wallace and Professor Gabrielle Hawksworth

Pre-requisites

MBChB or good Honours degree in Pharmacology, Pharmacy, Biochemistry or a related discipline.

Overview

Theory of microarray analyses, proteomics, transcriptomics, PCR, protein blotting.
Metabolic profiling.
Key features in the design of a research project.
Basic epidemiology.
Risk assessment in drug development.

Structure

12 x 1-hour lectures and 2 x tutorials, 1 x practical class.

Assessment

100% Continuous assessment: essay (35%); practical (35%); presentation (30%).

Credit Points

25

Course Coordinator

Dr Heather M Wallace

Pre-requisites

Attainment at the appropriate level in the taught courses of the Diploma/MSc Clinical Pharmacology common programme.

Co-requisites

Restricted to students on the Diploma in Clinical Pharmacology Programme.

Overview

Each dissertation is distinct and dependent on the student's interests and the work being pursued by research groups within the department at the time. All proposed dissertations are reviewed by the course coordinators and committee before being offered to the students.

Structure

No formal teaching during the research period. Departmental seminar - 1 hour per week.

Assessment

Thesis (80%)
Defence of Thesis at Viva (20%)

Credit Points

Course Coordinator

Dr Heather M Wallace

Pre-requisites

A Pass in each of the taught courses of the MSc Clinical Pharmacology programme.

Notes

Overview

Each project is distinct and is dependent on the work being pursued by research groups within the department at the time. All projects are reviewed by the course coordinators and committee before it is offered to the students.

Structure

No formal teaching during the research period. Departmental seminar - 1 hour per week.

Assessment

Thesis (60%)
Oral Presentation of Work (20%)
Defence of Thesis at Viva (20%)

Credit Points

90

Course Coordinator

Dr Lindsey Masson

Pre-requisites

This course is restricted to students on the MSc Human Nutrition & Metabolism programme. The Human Nutrition core course (MT5007), Applied Statistics course (PU5005 and the Human Nutrition and Metabolism (MT5401) taught courses are pre-requisites.

Overview

Full-time supervised research project on a topic related to human nutrition and metabolism in laboratory or clinical setting

Structure

Full-time research work as dictated by the specific project

Assessment

Thesis (University Examiner 25%; Rowett Examiner, 25%; External Examiner, 25%), Oral Presentation of Project Results (25%).

Credit Points

30

Course Coordinator

Dr Lindey Masson

Pre-requisites

This course is restricted to students on the PG Human Nutrition and Metabolism programme. The Human Nutrition core course and the Human Nutrition and Metabolism taught course are pre-requisites.

Overview

Full-time literature review on a topic related to human nutrition chosen by the student in consultation with an appointed supervisor

Structure

Full-time research work as dictated by the specific project.

Assessment

Dissertation 100%

Credit Points

20

Course Coordinator

Dr Heather Wallace

Pre-requisites

A pass in each of the taught courses in the MSc degree programmes for Drug Development and Drug Development and Bio-Business

Overview

Dissertation for candidates taking Postgraduate Diploma in Drug Development and Drug Development with Bio-Business

Structure

Assessment

Credit Points

Course Coordinator

Dr Heather Wallace

Pre-requisites

N/A

Notes

Overview

Research Project for Drug Development and Drug Development and Bio-Business MSc

Structure

Assessment

Credit Points

70

Course Coordinator

Dr Heather Wallace

Pre-requisites

Successful completion of all courses prescribed for MSc in Drug Development and Drug Safety.

Notes

Overview

Each project is unique and depends on the interests of the student and ongoing research work within the department. All proposed dissertation topics are reviewed by the committee before being offered to the students.

Structure

No formal teaching. One-to-one meetings with supervisor.

Assessment

Thesis (100%).