M.Sc., Ph.D., AFHEA.,
Advanced Research Fellow
- Email Address
- amalraj.raja@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437147
- Office Address
Telephone :01224-437147 Fax :01224 437857 Medical Statistics Team Division of Applied Health Sciences University of Aberdeen Polwarth Building Foresterhill ABERDEEN AB25 2ZD UK
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Edwin Amalraj Raja joined Public Health as a Research Fellow in Medical Statistics in May 2006. In 1983, Edwin Amalraj Raja got his undergraduate degree in Statistics from St.Joseph's College, Trichy, India and postgraduate degree in Statistics from Loyola College, Chennai, India.
Edwin Amalraj Raja completed advanced training on the application of Statistics in the Department of Biostatistics, Christian Medical College, Vellore. He worked in 'Advanced Center for Clinical Epidemiological Research and Training Centre' at Madras Medical College, Chennai. His work with the Tamil Nadu Government funded project on 'Epidemiology of Head Injury' led him to pursue and obtain his PhD in 'Biostatistical Application in the Prediction of Outcome of Severe Head Injury' from the Tamil Nadu M G R Medical University, Chennai, India.
Within Institute of Apllied Health Sciences (IAHS), Edwin Amalraj Raja is involved in the analysis of research projects, especially statistical modelling of longitudinal data, Statistical methods in Epidemiology, etc., He is also involved in teaching and training in Medical statistics organised by the Medical Statistics Team for staff and students of this University.
Memberships and Affiliations
Member of School Ethics Committee
Member of Health and Safety, School of Medicine
Statistical expert for North of Scotland Research Ethics Committee (NRES)
Research Overview
Clinical Areas of Consulting Experience
Obstetric & Gynaecology Factors associated with Maternal complications, Maternal BMI & Offspring CVD , Mortality
Infertility Classification of infertility and demographic factors affecting fertility
Maternal Obesity Offspring developing CVD
Renal disease The relationship between renal function parameters and blood pressure
common Cancers Factors contributing to time to consult GP, provider delay & stage , Mortality
Diabetes Mellitus Prevalence, risk factors, incidence of complications, patients perception of their complication
Current Research
Methodological research interests
Prediction Modelling
Categorical data analysis
Statistical methods in Epidemiology
Analysis of repeated measures / Longitudinal Data Analysis / Multilevel Modeling
Structural Equation Modelling
Cubic spline analysis - Non-linear relationship between continuous variable and outcome
Survival analysis- Competing risks- recurrent events
Supervision
Looking for a PhD student
Title: The impact of duration of freezing of IVF embryos on pregnancy and perinatal outcomes – analysis of UK national data
Background of the research proposal:
IVF (in-vitro fertilisation) is the recommended treatment for couples with unresolved infertility. It involves mixing eggs and sperm to create embryos which are then cultured in the laboratory. Usually, the best embryo is then put back in the womb, while others can be frozen for future use. The use of frozen embryos has become popular across the globe in recent years, accounting for 41% of all IVF treatments in 2019 in UK. Although many embryos are frozen for short durations, others can be kept in the freezer for many months or years and it is believed that patients can use them at any time without affecting their chances of pregnancy rates or the health of their babies.
Aim: To find an association between the duration of embryo freezing and pregnancy and perinatal outcomes among couples treated for infertility
Dataset: This study will use information of treatments undertaken between 2000 and 2019 from the Human Fertilisation Embryology Authority (HFEA) database which holds data of all IVF treatments undertaken in the UK licensed clinics, to explore the impact of the duration of embryo freezing on IVF live birth rate and safety of children.
Exposure: the duration of embryo freezing
Outcomes: The main outcome measures are live birth, gestational age (preterm vs term), birthweight (small/large for gestational age vs normal for gestational age) and congenital anomalies. The results of the proposed research will provide patients and clinicians with the necessary information so that they can make informed choices in the future.
Statistical Analyses: The student is expected to come up with appropriate statistical methods and use machine learning techniques to address the research question or objective of the study.
Funding and Grants
Murchie P, Lisa I, Raja EA, Lee AJ. Do melanoma excised in primary care have different outcomes to those excised in secondary care? Friends of ANCHOR £10,000
David M, Bhattacharya S, Abha M, Raja EA. Perinatal outcomes of singletons born following in-vitro fertilisation: a comparison of different embryo transfer strategies using UK data. NHS Grampian Endowment .(submitted)
Mairead B, Sohinee B, Andrea W, Gail F, EA Raja and Ipek. Maternal Body Mass Index in pregnancy ana cardiometabolic risk in monozygotic and dizygotic twin offspring (submitted to Wellbeing of Women)
Sohinee B, Geraldine M, Rebecca R and EA Raja. Reproductive consequences of third and fourth degree perineal tears (submitted to CHSS)
Teaching Responsibilities
Teaching in the Short courses organised by Medical Statistics Team
Introduction to Medical Statistics
Intermediate Statistics Course
B medical Science SPSS practicals II
M Sc Public Health practicals
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Cesarean section at full dilatation in the first birth is not associated with an increased risk of subsequent miscarriage: a historical cohort study
Woolner, A., Raja, E. A., Black, M.Acta Obstetricia et Gynecologica Scandinavica, vol. 103, no. 10, pp. 2092-2100Contributions to Journals: ArticlesInterrupted time series analysis of admissions before and after introduction of rapid review clinics in two centres
Chik, C. W., Christy, C. L. H., Raja, A., Turner, S. W.Archives of Disease in Childhood, vol. 109, no. 10, pp. 869-870Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/archdischild-2024-327314
- [ONLINE] View publication in Scopus
Paternal migration and child stunting in India: An analysis of NFHS-5 data.
Guntupalli, A., Gaur, K., Raja, E. A., Keshri, K.Economic and Political Weekly, vol. 59, no. 35Contributions to Journals: ArticlesIs arrival by ambulance a risk factor for myocardial infarction in emergency department patients with cardiac sounding chest pain?
Murray, J., Raja, E. A., Plascevic, J., Jacunski, M., Cooper, J. G.Emergency Medicine Journal, vol. 41, no. 6, pp. 376-378Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/emermed-2023-213643
- [ONLINE] View publication in Scopus
Risk of spontaneous preterm birth elevated after first cesarean delivery at full dilatation: a retrospective cohort study of over 30,000 women
Woolner, A., Raja, E. A., Bhattacharya, S., Black, M.American Journal of Obstetrics and Gynecology, vol. 230, no. 3, pp. 358.e1-358.e13Contributions to Journals: ArticlesPerinatal outcomes in singleton live births after blastocyst transfer: an analysis of 60,926 in vitro fertilization cycles from the United Kingdom
Marconi, N., Raja, E. A., Bhattacharya, S., Maheshwari, A.Fertility and Sterility, vol. 120, no. 2, pp. 312-320Contributions to Journals: ArticlesMaternal and perinatal outcomes of prolonged second stage of labour: a historical cohort study of over 51,000 women
Young, C., Bhattacharya, S., Woolner, A., Ingram, A., Smith, N., Raja, E., Black, M.BMC Pregnancy and Childbirth, vol. 23, no. 1, 467Contributions to Journals: ArticlesA comparison of perinatal outcomes following fresh blastocyst or cleavage stage embryo transfer in singletons and twins and between singleton siblings
Raja, E., Bhattacharya, S., Maheshwari, A., McLernon, D. J.Human Reproduction Open, vol. 2023, no. 2, hoad003Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/hropen/hoad003
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/20457/1/Raja_etal_HRO_A_Comparison_Of_VOR.pdf
- [ONLINE] View publication in Scopus
Comparison of perinatal outcomes following frozen or fresh embryo transfer: separate analyses of singleton, twin and sibling live births from a linked national In vitro fertilisation registry
Raja, E. A., Bhattacharya, S., Maheshwari, A., McLernon, D.Fertility and Sterility, vol. 118, no. 2, pp. 323-334Contributions to Journals: ArticlesReducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial
Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongste, J. C., Pijnenburg, M. W., Thomas, M., Price, D.The Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592Contributions to Journals: Articles