MAPS

Many men experience urinary incontinence after prostate surgery.

MAPS, funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme, is a multi-centre UK trial to evaluate whether pelvic floor muscle training and bladder training, delivered in four one-to-one sessions by a trained therapist (from a physiotherapy or nursing background), results in better urinary and other outcomes compared with standard management in men who are incontinent after prostate surgery. There are two contemporaneous but separate trials, one after radical prostatectomy for prostate cancer and the other after transurethral resection of the prostate (TURP) for benign prostatic enlargement.

MAPS began in December 2004. The aim was to recruit 800 men in total (400 to each of the trials). Recruitment to MAPS closed in September 2008, with 411 men recruited to the radical trial and 442 to the TURP.  The results have been disseminated by presentation at the International Continence Society / International UroGynaecology Association annual meeting (prize for best clinical abstract) and in an HTA Monograph, and in the Lancet.  Follow-up of the participants at two and four-to-six years has also been completed.

Contacts

• Cathryn Glazener; c.glazener@abdn.ac.uk

Status

Publications

Buckley B, Lapitan MC, Glazener C, MAPS Trial Group. The effect of urinary incontinence on health utility and health related quality of life in men following prostate surgery. Neurourol Urodyn 2012;31(4):465-9.

Glazener C, Boachie C, Buckley B, Cochran C, Dorey G, Grant A, Hagen S, Kilonzo M, McDonald A, McPherson G, Moore K, N'Dow J, Norrie J, Ramsay C, Vale L. Conservative treatment for urinary incontinence in Men After Prostate Surgery (MAPS): two parallel randomised controlled trials. Health Technol Assess 2011;15:24.

Glazener CM, Boachie C, Buckley B, Cochran C, Dorey G, Grant A, Hagen S, Kilonzo M, McDonald A, McPherson G, Moore K, Norrie J, Ramsay C, Vale L, N'Dow J. Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials. Lancet 2011;378(9788):328-37.

Glazener C. Protocol 07PRT/588: Conservative treatment for urinary incontinence in men after prostate surgery (MAPS): multicentre randomised controlled trial of pelvic floor muscle training (ISRCTN 87696430). Lancet [serial on the Internet]. 2004. Available from: URL:  http://www.lancet.com/protocol-reviews/07PRT-588.

Cochran C, Glazener C, McDonald A, Norrie J, MAPS Study Group.  Randomised control trial and error: the challenges of trial management in a geographically dispersed multi-centred trial. NHS Confederation Conference, Manchester, June 2008.

Cochran C, Glazener C, McDonald A, Norrie J, MAPS Study Group.  Randomised control trial and error: the challenges of trial management in a geographically dispersed multi-centred trial. Society for Clinical Trials, 29th Annual Meeting, St Louis, Missouri, 18-21 May 2008.

Dorey G, Glazener C, Buckley BS, Cochran C, Moore K. Developing a pelvic floor muscle training regimen for use in a trial intervention. Physiotherapy 2009;95(3):199-209.

Glazener C, Boachie C, Buckley BS, Cochran C, Dorey G, Grant AM et al.  A randomised controlled trial of conservative treatment (pelvic floor muscle training and bladder training) for urinary incontinence in men after prostate surgery (MAPS). ICS IUGA, Toronto, Canada, 23-27 August 2010.

Hagen S, Glazener C, Cochran C, Campbell L.  Continence care for men having prostate surgery: advice and practical help before and after radical prostatectomy and TURP. International Continence Society, 39th Annual Meeting, San Francisco, September 2009.

Hagen S, Glazener C, Cochran C, Campbell L.  Continence care for men having prostate surgery: advice and practical help before and after radical prostatectomy and TURP. RCN International Research Conference, 24-27 March, Cardiff 2009.

Hagen S, Glazener C, Boachie C, Buckley BS, Cochran C, Dorey G et al.  Urinary incontinence and erectile dysfunction after radical prostatectomy: association with route and technique of operation. ICS IUGA, Toronto, Canada, 23-27 August 2010.

McDonald A, McPherson GC.  Design of the men after prostate surgery study (MAPS): two contemporaneous trials running alongside one another. Society for Clinical Trials, 27th Annual Meeting, Orlando, Florida, 21-24 May 2006.

McDonald A, McPherson GC, Glazener CM, Norrie J, MAPS Study Group. Design of the Men After Prostate Surgery study (MAPS): two contemporaneous trials running alongside one another [abstract]. Clin Trials 2006;3(Suppl 1):243.