HOME | CONTACTS | INTRANET

• About the School
• Medical and Dental Education
• Applied Medicine

STAFF SEARCH

Professor Michael Greaves The University of Aberdeen School of Medicine & Dentistry Vice Principal and Head of College work +44 (0)1224 437082 work fax +44 (0)1224 437069 pref m.greaves@abdn.ac.uk pref College Office College of Life Sciences and Medicine Polwarth Building Foresterhill Aberdeen AB25 2ZD m.greaves@abdn.ac.uk PA: Liza Young - +44 (0)1224 437082, liza.young@abdn.ac.uk

---

Biography

Mike Greaves graduated in Medicine, with Honours, from Sheffield University in 1972 and developed an interest in haematology shortly thereafter. He trained in internal medicine within the United Sheffield Hospitals before taking up a temporary Lectureship to work on the area of Bone Resorption in Malignancy. Following this he spent two years in Australia, firstly at the Austin Hospital in Melbourne and then in the Westmead Hospital in Sydney undergoing specialist training in haematology and carrying out research into haemostasis. He returned to Sheffield as Lecturer in 1981, later becoming Senior Lecturer and Reader. He was appointed Professor of Haematology in Aberdeen in 1996, Head of Department of Medicine & Therapeutics in 1999, Deputy Dean of the Faculty of Medicine and Medical Sciences in 2002 and Head of the School of Medicine in 2003.

From 1 September 2011, Professor Greaves is a Vice-Principal of the University and Head of the College of Life Sciences and Medicine.

^ top

Research Interests

Professor Greaves has published extensively on haematological topics, particularly in relation to haemostasis, thrombosis and myeloma. Current research activity is also in these areas, with an emphasis on the pathogenesis and management of thrombotic disease. His clinical work is in the area of general haematology, haemostasis and thrombosis.

^ top

National and International Responsibilities

Professor Greaves has been President of the British Society for Haematology, the British Society for Haemostasis & Thrombosis and the Scottish Haematology Society. He has served as Chairman of the National Quality Assurance Panel for Haematology and the Control of Anticoagulation Sub-committee of the International Society for Thrombosis & Haemostasis. He is Chairman of the Specialty Advisory Committee for Haematology of the JCHMT and a member of the Curriculum Committee of the European Haematology Association. He is a former editor of the British Journal of Haematology and is Co-Editor in Chief elect of the Journal of Thrombosis & Haemostasis.

^ top

Publications

Contributions to Journals

Articles

• Keeling, D., Mackie, I., Moore, GW., Greer, IA. & Greaves, M. (2012). 'Guidelines on the investigation and management of antiphospholipid syndrome'. British Journal of Haematology, vol 157, no. 1, pp. 47-58.
  [Online] DOI: 10.1111/j.1365-2141.2012.09037.x
• Halawani, SH., Williams, D., Adefurin, A., Webster, J., Greaves, M. & Ford, I. (2011). 'Aspirin failure in patients presenting with acute cerebrovascular ischaemia'. Thrombosis & Haemostasis, vol 106, no. 2, pp. 240-247.
• Greaves, M. (2011). 'Antiphospholipid syndrome: Unusual clinical presentations'. Thrombosis Research, vol 127, no. suppl3, pp. s47-50.
  [Online] DOI: 10.1016/S0049-3848(11)70013-5
• Clark, P., Walker, ID., Langhorne, P., Crichton, L., Thomson, A., Greaves, M., Whyte, S. & Greer, IA. (2010). 'SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage'. Blood, vol 115, no. 21, -, pp. 4162-4167.
  [Online] DOI: 10.1182/blood-2010-01-267252
• Baglin, T., Gray, E., Greaves, M., Hunt, BJ., Keeling, D., Machin, SJ., Mackie, IJ., makris, M., NOKES, T., Perry, D., Tait, RC., Walker, I. & Watson, H. (2010). 'Clinical guidelines for testing for heritable thrombophilia'. British Journal of Haematology, vol 149, no. 2, pp. 209-220.
  [Online] DOI: 10.1111/j.1365-2141.2009.08022.x
• Norrie, G., Farquharson, RG. & Greaves, M. (2009). 'Screening and treatment for heritable thrombophilia in pregnancy failure: inconsistencies among UK early pregnancy units'. British Journal of Haematology, vol 144, no. 2, pp. 241-244.
  [Online] DOI: 10.1111/j.1365-2141.2008.07444.x
• Graham, A., Ford, I., Morrison, R., Barker, RN., Greaves, M. & Erwig, LP. (2009). 'Anti-endothelial antibodies interfere in apoptotic cell clearance and promote thrombosis in patients with antiphospholipid syndrome'. Journal of Immunology, vol 182, no. 3, pp. 1756-1762.
• Greaves, M. (2009). 'Pathogenesis and management of antiphospholipid syndrome'. Thrombosis Research, vol 123, no. Supplement 2, pp. s4-s9.
  [Online] DOI: 10.1016/S0049-3848(09)70002-7
• Watson, HG. & Greaves, M. (2008). 'Can we predict bleeding?'. Seminars in Thrombosis and Hemostasis, vol 34, no. 1, pp. 97-103.
  [Online] DOI: 10.1055/s-2008-1066028
• Chee, YL., Crawford, JC., Watson, HG. & Greaves, M. (2008). 'Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures'. British Journal of Haematology, vol 140, no. 5, pp. 496-504.
  [Online] DOI: 10.1111/j.1365-2141.2007.06968.x
• Greaves, M. & Watson, HG. (2007). 'Approach to the diagnosis and management of mild bleeding disorders'. Journal of Thrombosis and Haemostasis, vol 5, no. Suppl. 1, pp. 167-174.
  [Online] DOI: 10.1111/j.1538-7836.2007.02495.x
• Wu, O., Robertson, L., Twaddle, S., Lowe, GD., Clark, P., Greaves, M., Walker, ID., Langhorne, P., Brenkel, I., Regan, L. & Greer, I. (2006). 'Screening for thrombophilia in high risk situations: a systematic review and cost-effectiveness analysis. The Thrombosis Risk and Economic Assessment of Thrombophilia Screening [TREATS] study'. Health Technology Assessment, vol 10, no. 11, pp. 1-110.
• Cassar, K., Bachoo, P., Ford, I., Greaves, M. & Brittenden, J. (2006). 'Variabilty in responsiveness to clopidogrel in patients with intermittent claudication'. European Journal of Vascular and Endovascular Surgery, vol 32, no. 1, pp. 71-75.
  [Online] DOI: 10.1016/j.ejvs.2006.01.013
• Patterson, AM., Ford, I., Graham, A., Booth, N. & Greaves, M. (2006). 'The influence of anti-endothelial/antiphospholipid antibodies on fibrin formation and lysis on endothelial cells'. British Journal of Haematology, vol 133, no. 3, pp. 323-330.
  [Online] DOI: 10.1111/j.1365-2141.2006.05994.x
• Baglin, T., Barrowcliffe, TW., Cohen, A., Greaves, M. & British Comm Stand Haematology (2006). 'Guidelines on the use and monitoring of heparin'. British Journal of Haematology, vol 133, no. 1, pp. 19-34.
  [Online] DOI: 10.1111/j.1365-2141.2005.05953.x
• Robertson, L., Wu, O., Langhorne, P., Twaddle, S., Clark, P., Lowe, GD., Walker, ID., Greaves, M., Brenkel, I., Regan, L. & Greer, I. (2006). 'Thrombophilia in pregnancy: a systematic review'. British Journal of Haematology.
• Collins, P., Ford, I., Greaves, M., MacAulay, E. & Brittenden, J. (2006). 'Surgical revascularisation in patients with severe limb ischaeia induces a prothrombotic state'. Platelets, vol 117, pp. 311-317.
• Toff, WD., Jones, CI., Ford, I., Pearse, RJ., Watson, HG., Watt, SJ., Ross, JAS., Gradwell, DP., Batchelor, AJ., Abrams, KR., Meijers, JCM., Goodall, AH. & Greaves, M. (2006). 'Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function and endothelial activation'. Journal of the American Medical Association, vol 295, no. 19, pp. 2251-2261.
  [Online] DOI: 10.1001/jama.295.19.2251
• Collins, P., Ford, I., Ball, DR., MacAulay, E., Greaves, M. & Brittenden, J. (2006). 'A preliminary study on the effects of exercising to maximum walking distance on platelet and endothelial function in patients with intermittent claudication'. European Journal of Vascular and Endovascular Surgery, vol 31, no. 3, pp. 266-273.
  [Online] DOI: 10.1016/j.ejvs.2005.10.011
• Collins, P., Ford, I., Croal, BL., Ball, D., Greaves, M., MacAulay, E. & Brittenden, J. (2006). 'Haemostasis, inflammation and renal function following exercise in patients with intermittent claudication on statin and aspirin therapy'. Thrombosis Journal, vol 4, no. 9, pp. 1-8.
  [Online] DOI: 10.1186/1477-9560-4-9
• Collins, P., Ford, I., Greaves, M., MacAulay, E. & Brittenden, J. (2006). 'Surgical revascularisation in patients with severe limb ischaemia induces a pro-thrombotic state'. Platelets, vol 17, no. 5, pp. 311-317.
  [Online] DOI: 10.1080/09537100600746540
• Wu, O., Robertson, L., Langhorne, P., Twaddle, S., Lowe, GDO., Clark, P., Greaves, M., Walker, ID., Brenkel, I., Regan, L. & Greer, I. (2005). 'Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review'. Thrombosis & Haemostasis, vol 94, no. 1, pp. 17-25.
• Gilmour, PS., Morrison, ER., Henriksen, P., Vickers, MA., Ford, I., Greaves, M., Donaldson, K. & MacNee, W. (2005). 'Pro-coagulant effects of environmental particles (PM10)'. Occupational and Environmental Medicine, vol 62, pp. 164-171.
  [Online] DOI: 10.1136/oem.2004.014951
• Cassar, K., Ford, I., Greaves, M., Bachoo, P. & Brittenden, J. (2005). 'Randomized clinical trial of the antiplatelet effects of aspirin-clopidogrel combination versus aspirin alone after lower limb angioplasty'. British Journal of Surgery, vol 92, no. 2, pp. 159-165.
  [Online] DOI: 10.1002/bjs.4810
• Cassar, K., Bachoo, P., Ford, I., Greaves, M. & Brittenden, J. (2005). 'Clopidogrel has no effect on D-dimer and thrombin-antithrombin III levels in patients with peripheral arterial disease undergoing peripheral percutaneous transluminal angioplasty'. Journal of Vascular Surgery, vol 42, no. 2, pp. 252-258.
  [Online] DOI: 10.1016/j.jvs.2005.04.027
• Cassar, K., Bachoo, P., Ford, I., Greaves, M. & Brittenden, J. (2005). 'Markers of coagulation activation, endothelial stimulation and inflammation in patients with peripheral arterial disease'. European Journal of Vascular and Endovascular Surgery, vol 29, no. 2, pp. 171-176.
  [Online] DOI: 10.1016/j.ejvs.2004.11.001
• Moir, E., Greaves, M., Adey, GD. & Bennett, B. (2004). 'Polymorphonuclear leukocytes from patients with severe sepsis have lost the ability to degrade fibrin via u-PA'. Journal of Leukocyte Biology, vol 76, pp. 571-576.
  [Online] DOI: 10.1189/jlb.0502257
• Greaves, M. (2004). 'ES04.02 Assessment of haemostasis'. Vox Sanguinis, vol 87 Suppl 1, pp. 47-50.
  [Online] DOI: 10.1111/j.1741-6892.2004.00429.x
• Gilmour, PS., Ziesenis, A., Morrison, ER., Vickers, MA., Drost, EM., Ford, I., Karg, E., Mossa, C., Schroeppel, A., Ferron, GA., Heyder, J., Greaves, M., MacNee, W. & Donaldson, K. (2004). 'Pulmonary and systemic effects of short-term inhalation exposure to ultrafine carbon black particles'. Toxicology and Applied Pharmacology, vol 195, pp. 35-44.
  [Online] DOI: 10.1016/j.taap.2003.10.003
• Cassar, K., Bachoo, P., Ford, I., McGee, M., Greaves, M. & Brittenden, J. (2004). 'Helicobacter pylori seropositivity is associated with enhanced platelet activation in patients with intermittent claudication'. Journal of Vascular Surgery, vol 39, no. 3, pp. 560-564.
  [Online] DOI: 10.1016/j.jvs.2003.09.042
• Vickers, MA., Ford, I., Morrison, R., Prescott, GJ., Watson, S., Hannaford, PC., Smith, WCS., Campbell, DM. & Greaves, M. (2003). 'Markers of endothelial activation and atherothrombosis in women with history of pre-eclampsia or gestational hypertension'. Thrombosis & Haemostasis, vol 90, no. 6, pp. 1192-1197.
  [Online] DOI: 10.1160/TH03-01-0053
• Greaves, M. & Watson, HG. (2003). 'Laboratory testing for prothrombotic states: clinical utility'. Current Hematology Reports, vol 2, no. 5, pp. 429-434.
• Chisholm, R. & Greaves, M. (2003). 'Role of coagulation testing in predicting bleeding risk'. Hematology Journal, vol 4, no. 6, pp. 373-378.
  [Online] DOI: 10.1038/sj.thj.6200306
• Cassar, K., Bachoo, P., Greaves, M., Brittenden, J. & Ford, I. (2003). 'Platelet activation is increased in peripheral arterial disease'. Journal of Vascular Surgery, vol 38, no. 1, pp. 99-103.
  [Online] DOI: 10.1016/S0741-5214(03)00129-0
• Morrison, ER., Miedzybrodzka, ZH., Campbell, DM., Haites, NE., Wilson, B., Watson, M., Greaves, M. & Vickers, MA. (2002). 'Prothrombotic genotypes are not associated with pre-eclampsia and gestational hypertension: results from a large population-based study and systematic review'. Thrombosis & Haemostasis, vol 87, no. 5, pp. 779-785.
• Greaves, M. (2002). 'Limitations of the laboratory monitoring of heparin therapy. Scientific and Standardization Committee Communications: on behalf of the Control of Anticoagulation Subcommittee of the Scientific and Standardization Committee of the International Society of'. Thrombosis & Haemostasis, vol 87, no. 1, pp. 163-164.
• Farquharson, RG., Quenby, S. & Greaves, M. (2002). 'Antiphospholipid syndrome in pregnancy: a randomised, controlled trial of treatment'. Obstetrics & Gynecology, vol 100, pp. 408-413.
  [Online] DOI: 10.1016/S0029-7844(02)02165-8
• Ozturk, O., Greaves, M. & Templeton, AA. (2002). 'Aspirin dilemma. Remodelling the hypothesis from a fertility perspective'. Human Reproduction, vol 17, no. 5, pp. 1146-1148.
  [Online] DOI: 10.1093/humrep/17.5.1146
• Jennings, I., Greaves, M., Mackie, IJ., Kitchen, S., Woods, TA., Preston, FE. & UK Natl External Quality Assessmen (2002). 'Lupus anticoagulant testing: improvements in performance in a UK NEQASproficiency testing exercise after distribution of guidelines on laboratory methods'. British Journal of Haematology, vol 119, pp. 364-369.
  [Online] DOI: 10.1046/j.1365-2141.2002.03821.x
• Salah-Uddin, H., Gordon, MJ., Ford, I., Tandon, NN., Greaves, M. & Dutta Roy, AK. (2002). 'Surface expression of fatty acid translocase [FAT/CD36] on platelets in myeloproliferative disease and non-insulin dependent diabetes mellitus: effect on arachidonic acid uptake'. Molecular & Cellular Biochemistry, vol 239, pp. 203-211.
  [Online] DOI: 10.1023/A:1020583630536
• Bodie, SL., Ford, I., Greaves, M. & Nixon, GF. (2001). 'Thrombin-induced activation of RhoA in platelet shape change'. Biochemical and Biophysical Research Communications, vol 287, no. 1, pp. 71-76.
  [Online] DOI: 10.1006/bbrc.2001.5547
• Meiklejohn, DJ., Vickers, MA., Morrison, ER., Dijkhuisen, R., Moore, I., Urbaniak, S. & Greaves, M. (2001). 'In vivo platelet activation in atherothrombotic stroke is not determined by polymorphisms of human platelet glycoprotein IIIa or Ib'. British Journal of Haematology, vol 112, no. 3, pp. 621-631.
  [Online] DOI: 10.1046/j.1365-2141.2001.02620.x
• Ford, I., Cotter, MA., Greaves, M. & Cameron, NE. (2001). 'The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat'. Metabolism, vol 50, no. 8, pp. 868-875.
  [Online] DOI: 10.1053/meta.2001.24914
• Watson, HG., Chisholm, R. & Greaves, M. (2001). 'Rare acquired bleeding disorders'. Reviews in Clinical and Experimental Hematology, vol 5, no. 4, pp. 405-429.
  [Online] DOI: 10.1046/j.1468-0734.2001.00050.x
• Meiklejohn, DJ., Vickers, MA., Dijkhuisen, R. & Greaves, M. (2001). 'Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke'. Stroke, vol 32, no. 1, pp. 57-62.
• Greaves, M. (2001). 'Thrombophilia'. Clinical Medicine, vol 1, no. 6, pp. 432-435.
• Scott, JA., Arnold, JJ., Broadfoot, CJ., Graham, A., Kirkpatrick, JN., Greaves, M., Currie, JM. & Davidson, M. (2001). 'No excess of factor V:Q506 genotype but high prevalence of anticardiolipin antibodies without antiendothelial cell antibodies in retinal vein occlusion in young patients'. Ophthalmologica, vol 215, no. 3, pp. 217-221.
  [Online] DOI: 10.1159/000050862
• Greaves, M., Cohen, H., Machin, SJ. & Mackie, I. (2000). 'Pathogenesis and management of antiphospholipid syndrome'. Thrombosis Research, vol 109, no. 4, pp. 704-715.
  [Online] DOI: 10.1046/j.1365-2141.2000.02069x

Letters

• Clark, P., Meiklejohn, DJ., O'Sullivan, A., Vickers, MA. & Greaves, M. (2005). 'The relationships of ABO, Lewis and secretor blood groups with cerebral ischaemia of arterial origin'. Journal of Thrombosis and Haemostasis, vol 3, no. 9, pp. 2105-2108.
  [Online] DOI: 10.1111/j.1538-7836.2005.01535.x

Scientific Reviews

• Merriman, L. & Greaves, M. (2006). 'Testing for thrombophilia: an evidence-based approach'. Postgraduate Medical Journal, vol 82, pp. 699-704.
  [Online] DOI: 10.1136/pgmj.2006.048090

Editorials

• Greaves, M. & Lane, DA. (2007). 'Testimony and new challenges'. Journal of Thrombosis and Haemostasis, vol 5, no. 3, pp. 448-449.
  [Online] DOI: 10.1111/j.1538-7836.2007.02413.x
• Greaves, M. (2005). 'Antiphospholipid syndrome: Clinical Manifestations and Management'. Thrombosis Research, vol 115, no. suppl 1, pp. 27-30.
• Vickers, MA. & Greaves, M. (2005). 'The cryptic path from epitope to clot: a story of two domains?'. Blood, vol 105, pp. 1371-1372.
  [Online] DOI: 10.1182/blood-2004-11-4556
• Greaves, M. (2005). 'Pharmacogenetics in the management of coumarin anticoagulant therapy : the way forward or an expensive diversion?'. PLoS Medicine, vol 2, no. 10.
  [Online] DOI: 10.1371/journal.pmed.0020342
• Greaves, M. (2004). 'Masterclass series in peripheral arterial disease: Acquired thrombophilia'. Vascular Medicine, vol 9, no. 3, pp. 215-218.
  [Online] DOI: 10.1191/1358863x04vm533xx
• Murray, ET. & Greaves, M. (2003). 'INRs and point of care testing'. British Medical Journal, vol 37, pp. 5-6.
  [Online] DOI: 10.1136/bmj.327.7405.5

Chapters in Books, Reports and Conference Proceedings

Chapters

• Greaves, M. & Culligan, DJ. (2004). 'Blood and bone marrow'. in JCE Underwood (ed.), General and systematic pathology. 4th edn, Churchill Livingstone, Edinburgh, pp. 615-672.
• Watson, HG. & Greaves, M. (2001). 'Exercise in subjects with haematological disorders'. in Sports medicine for specific ages and abilities, Eds: Maffulli, Chan, MacDonald, Malina, Parker Churchill Livingstone. Sports medicine for specific ages and abilities, Eds: Maffulli, Chan, MacDonald, Malina, Parker Churchill Livingstone, pp. 405-416.
• Greaves, M. & Preston, FE. (2001). 'Approach to the bleeding patient'. in Haemostasis and thrombosis: Basic principles and clinical practice Eds: Colman, Hirsh, Marder, Clowes, George Lippincott Williams and Wilkins. Haemostasis and thrombosis: Basic principles and clinical practice Eds: Colman, Hirsh, Marder, Clowes, George Lippincott Williams and Wilkins.
• Maughan, RJ., Leiper, JB. & Greaves, M. (2001). 'Haematology'. in In:Kinanthropometry and exercise physiology laboratory manual, volume 2: Exercise Physiology. In:Kinanthropometry and exercise physiology laboratory manual, volume 2: Exercise Physiology, pp. 99-116.

^ top

update | about Staff Pages

‹ back